Publications by authors named "Vyacheslav Filichev"

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Controlling Topology of a Telomeric G-quadruplex DNA With a Chemical Cross-link.
Bruce Chilton, Patrick J B Edwards, Geoffrey B Jameson, Tracy K Hale, Vyacheslav V Filichev

Chemistry· July 2025

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Inverted strand polarity yields thermodynamically stable G-quadruplexes and prevents duplex formation within extended DNA.
Bruce Chilton, Ruby J Roach, Patrick J B Edwards, Geoffrey B Jameson, Tracy K Hale, Vyacheslav V Filichev

Chem Sci· August 2024

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Synthesis of 1,4-azaphosphinine nucleosides and evaluation as inhibitors of human cytidine deaminase and APOBEC3A.
Maksim V Kvach, Stefan Harjes, Harikrishnan M Kurup, Geoffrey B Jameson, Elena Harjes, Vyacheslav V Filichev

Beilstein J Org Chem· May 2024

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Understanding intercalative modulation of G-rich sequence folding: solution structure of a TINA-conjugated antiparallel DNA triplex.
Miguel Garavís, Patrick J B Edwards, Israel Serrano-Chacón, Osman Doluca, Vyacheslav V Filichev

Nucleic Acids Res· March 2024

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Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A.
Stefan Harjes, Harikrishnan M Kurup, Amanda E Rieffer, Maitsetseg Bayarjargal, Jana Filitcheva, Vyacheslav V Filichev

Nat Commun· October 2023

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Seven-membered ring nucleobases as inhibitors of human cytidine deaminase and APOBEC3A.
Harikrishnan M Kurup, Maksim V Kvach, Stefan Harjes, Geoffrey B Jameson, Elena Harjes, Vyacheslav V Filichev

Org Biomol Chem· June 2023

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Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A.
Stefan Harjes, Harikrishnan M Kurup, Amanda E Rieffer, Maitsetseg Bayaijargal, Jana Filitcheva, Vyacheslav V Filichev

bioRxiv· February 2023

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Design, Synthesis, and Evaluation of a Cross-Linked Oligonucleotide as the First Nanomolar Inhibitor of APOBEC3A.
Harikrishnan M Kurup, Maksim V Kvach, Stefan Harjes, Fareeda M Barzak, Geoffrey B Jameson, Vyacheslav V Filichev

Biochemistry· November 2022

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Small-Angle X-ray Scattering (SAXS) Measurements of APOBEC3G Provide Structural Basis for Binding of Single-Stranded DNA and Processivity.
Fareeda M Barzak, Timothy M Ryan, Nazanin Mohammadzadeh, Stefan Harjes, Maksim V Kvach, Vyacheslav V Filichev

Viruses· September 2022

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Phosphorothioate modification improves exon-skipping of antisense oligonucleotides based on sulfonyl phosphoramidates in mouse myotubes.
Yongdong Su, Prithi Raguraman, Rakesh N Veedu, Vyacheslav V Filichev

Org Biomol Chem· May 2022

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Uncoupling Molecular Testing for SARS-CoV-2 From International Supply Chains.
Jo-Ann L Stanton, Rory O'Brien, Richard J Hall, Anastasia Chernyavtseva, Hye Jeong Ha, Vyacheslav V Filichev

Front Public Health· February 2022

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DNA with zwitterionic and negatively charged phosphate modifications: Formation of DNA triplexes, duplexes and cell uptake studies.
Yongdong Su, Maitsetseg Bayarjargal, Tracy K Hale, Vyacheslav V Filichev

Beilstein J Org Chem· March 2021

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Small-Angle X-ray Scattering Models of APOBEC3B Catalytic Domain in a Complex with a Single-Stranded DNA Inhibitor.
Fareeda M Barzak, Timothy M Ryan, Maksim V Kvach, Harikrishnan M Kurup, Hideki Aihara, Vyacheslav V Filichev

Viruses· February 2021

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The Importance of Phosphates for DNA G-Quadruplex Formation: Evaluation of Zwitterionic G-Rich Oligodeoxynucleotides.
Yongdong Su, Patrick J B Edwards, Dmitry A Stetsenko, Vyacheslav V Filichev

Chembiochem· September 2020

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Differential Inhibition of APOBEC3 DNA-Mutator Isozymes by Fluoro- and Non-Fluoro-Substituted 2'-Deoxyzebularine Embedded in Single-Stranded DNA.
Maksim V Kvach, Fareeda M Barzak, Stefan Harjes, Henry A M Schares, Harikrishnan M Kurup, Vyacheslav V Filichev

Chembiochem· April 2020

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Heterochromatin protein 1α interacts with parallel RNA and DNA G-quadruplexes.
Ruby J Roach, Miguel Garavís, Carlos González, Geoffrey B Jameson, Vyacheslav V Filichev

Nucleic Acids Res· January 2020

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Selective inhibition of APOBEC3 enzymes by single-stranded DNAs containing 2'-deoxyzebularine.
Fareeda M Barzak, Stefan Harjes, Maksim V Kvach, Harikrishnan M Kurup, Geoffrey B Jameson, Vyacheslav V Filichev

Org Biomol Chem· November 2019

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Effects of Pressure and pH on the Physical Stability of an I-Motif DNA Structure.
Christopher P Lepper, Martin A K Williams, Patrick J B Edwards, Vyacheslav V Filichev, Geoffrey B Jameson

Chemphyschem· June 2019

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Neutral and Negatively Charged Phosphate Modifications Altering Thermal Stability, Kinetics of Formation and Monovalent Ion Dependence of DNA G-Quadruplexes.
Yongdong Su, Hirofumi Fujii, Ekaterina A Burakova, Boris P Chelobanov, Masayuki Fujii, Vyacheslav V Filichev

Chem Asian J· April 2019

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α-2'-Deoxyguanosine can switch DNA G-quadruplex topologies from antiparallel to parallel.
Jana Filitcheva, Patrick J B Edwards, Gillian E Norris, Vyacheslav V Filichev

Org Biomol Chem· April 2019

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Inhibiting APOBEC3 Activity with Single-Stranded DNA Containing 2'-Deoxyzebularine Analogues.
Maksim V Kvach, Fareeda M Barzak, Stefan Harjes, Henry A M Schares, Geoffrey B Jameson, Vyacheslav V Filichev

Biochemistry· February 2019

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Silencing of BCR/ABL Chimeric Gene in Human Chronic Myelogenous Leukemia Cell Line K562 by siRNA-Nuclear Export Signal Peptide Conjugates.
Yasuhiro Shinkai, Shinichi Kashihara, Go Minematsu, Hirofumi Fujii, Madoka Naemura, Vyacheslav V Filichev

Nucleic Acid Ther· June 2017

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NMR-based method of small changes reveals how DNA mutator APOBEC3A interacts with its single-stranded DNA substrate.
Stefan Harjes, Geoffrey B Jameson, Vyacheslav V Filichev, Patrick J B Edwards, Elena Harjes

Nucleic Acids Res· May 2017

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DNA G-quadruplexes show strong interaction with DNA methyltransferases in vitro.
Simone L Cree, Rayleen Fredericks, Allison Miller, F Grant Pearce, Vyacheslav Filichev

FEBS Lett· September 2016

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Application of Cu(I)-catalyzed azide-alkyne cycloaddition for the design and synthesis of sequence specific probes targeting double-stranded DNA.
Svetlana V Vasilyeva, Vyacheslav V Filichev, Alexandre S Boutorine

Beilstein J Org Chem· August 2016

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