Publications by authors named "WR Swindell"

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Evaluating the Current Opioid Misuse Measure (COMM) as a Tool to Inform Management of Vaso-occlusive Episodes among Hospitalized Sickle Cell Disease Patients.
William R Swindell, Emmanuel Johnson, Min Yi, Augustine Joseph, Michael Burton

Clin J Pain· November 2025

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Meta-Analysis of Gene Expression in Bulk-Processed Post-Mortem Spinal Cord from ALS Patients and Normal Controls.
William R Swindell

NeuroSci· July 2025

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VGLL3-centered network connects placental, vascular, and immune defects in preeclampsia.
Olesya Plazyo, Laura B Chopp, Rishyanth Peela, Kelly Young, Haihan Zhang, William R Swindell

bioRxiv· June 2025

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A Novel Butyrate Derivative, Zinc Dibutyroyllysinate, Blunts Microphthalmia-Associated Transcription Factor Expression and Up-Regulates Retinol and Differentiation Pathway mRNAs in a Full-Thickness Human Skin Model.
William R Swindell, Krzysztof Bojanowski, Geovani Quijas, Ratan K Chaudhuri

Int J Mol Sci· March 2025

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Deletion of adipocyte Sine Oculis Homeobox Homolog 1 prevents lipolysis and attenuates skin fibrosis.
Nancy Wareing, Tingting W Mills, Scott Collum, Minghua Wu, Lucy Revercomb, William R Swindell

bioRxiv· July 2024

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Meta-analysis of differential gene expression in lower motor neurons isolated by laser capture microdissection from post-mortem ALS spinal cords.
William R Swindell

Front Genet· April 2024

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Formylpeptide receptor 1 contributes to epidermal barrier dysfunction-induced skin inflammation through NOD-like receptor C4-dependent keratinocyte activation.
Shuai Shao, Zhongbin Sun, Mengyang Chu, Jiaoling Chen, Tianyu Cao, William R Swindell

Br J Dermatol· March 2024

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Suppression of TCF4 promotes a ZC3H12A-mediated self-sustaining inflammatory feedback cycle involving IL-17RA/IL-17RE epidermal signaling.
Yanyun Jiang, Dennis Gruszka, Chang Zeng, William R Swindell, Christa Gaskill

JCI Insight· March 2024

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A Critical Role for IFN-β Signaling for IFN-κ Induction in Keratinocytes.
Bin Xu, Jon Musai, Yee Sun Tan, Grace A Hile, William R Swindell

Front Lupus· March 2024

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HERC6 regulates STING activity in a sex-biased manner through modulation of LATS2/VGLL3 Hippo signaling.
Ranjitha Uppala, Mrinal K Sarkar, Kelly Z Young, Feiyang Ma, Pritika Vemulapalli, William R Swindell

iScience· February 2024

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Bakuchiol and Ethyl (Linoleate/Oleate) Synergistically Modulate Endocannabinoid Tone in Keratinocytes and Repress Inflammatory Pathway mRNAs.
William R Swindell, Krzysztof Bojanowski, Parvesh Singh, Manpreet Randhawa, Ratan K Chaudhuri

JID Innov· May 2023

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Acetyl Zingerone: A Photostable Multifunctional Skincare Ingredient That Combats Features of Intrinsic and Extrinsic Skin Aging.
Thomas A Meyer, William R Swindell, Ratan K Chaudhuri

Antioxidants (Basel)· May 2023

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Differential cell composition and split epidermal differentiation in human palm, sole, and hip skin.
Julie Wiedemann, Allison C Billi, Federico Bocci, Ghaidaa Kashgari, Enze Xing, William R Swindell

Cell Rep· January 2023

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Metformin has heterogeneous effects on model organism lifespans and is beneficial when started at an early age in Caenorhabditis elegans: A systematic review and meta-analysis.
Austin J Parish, William R Swindell

Aging Cell· December 2022

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Isosorbide Fatty Acid Diesters Have Synergistic Anti-Inflammatory Effects in Cytokine-Induced Tissue Culture Models of Atopic Dermatitis.
William R Swindell, Krzysztof Bojanowski, Ratan K Chaudhuri

Int J Mol Sci· November 2022

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Large-scale analysis of longitudinal skin gene expression in systemic sclerosis reveals relationships of immune cell and fibroblast activity with skin thickness and a trend towards normalisation over time.
Brian Skaug, Marka A Lyons, William R Swindell, Gloria A Salazar, Minghua Wu

Ann Rheum Dis· April 2022

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Transcriptomic Analysis of Fumarate Compounds Identifies Unique Effects of Isosorbide Di-(Methyl Fumarate) on NRF2, NF-kappaB and IRF1 Pathway Genes.
William R Swindell, Krzysztof Bojanowski, Ratan K Chaudhuri

Pharmaceuticals (Basel)· April 2022

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Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor.
Lisa M Godsel, Quinn R Roth-Carter, Jennifer L Koetsier, Lam C Tsoi, Amber L Huffine, William R Swindell

J Clin Invest· February 2022

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A Sensitization-Free Dimethyl Fumarate Prodrug, Isosorbide Di-(Methyl Fumarate), Provides a Topical Treatment Candidate for Psoriasis.
Krzysztof Bojanowski, Collins U Ibeji, Parvesh Singh, William R Swindell, Ratan K Chaudhuri

JID Innov· December 2021

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IRAK2 Has a Critical Role in Promoting Feed-Forward Amplification of Epidermal Inflammatory Responses.
Shuai Shao, Lam C Tsoi, William R Swindell, Jiaoling Chen, Ranjitha Uppala

J Invest Dermatol· October 2021

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Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris.
Shuai Shao, Jiaoling Chen, William R Swindell, Lam C Tsoi, Xianying Xing

JCI Insight· October 2021

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Tetrahexyldecyl Ascorbate (THDC) Degrades Rapidly under Oxidative Stress but Can Be Stabilized by Acetyl Zingerone to Enhance Collagen Production and Antioxidant Effects.
William R Swindell, Manpreet Randhawa, Geovani Quijas, Krzysztof Bojanowski, Ratan K Chaudhuri

Int J Mol Sci· August 2021

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Isosorbide Di-(Linoleate/Oleate) Stimulates Prodifferentiation Gene Expression to Restore the Epidermal Barrier and Improve Skin Hydration.
Krzysztof Bojanowski, William R Swindell, Shyla Cantor, Ratan K Chaudhuri

J Invest Dermatol· June 2021

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A simple ABCD score to stratify patients with respect to the probability of survival following in-hospital cardiopulmonary resuscitation.
William R Swindell, Christopher G Gibson

J Community Hosp Intern Med Perspect· May 2021

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A standardized Terminalia chebula fruit extract alters the expression of genes associated with skin architecture and barrier formation.
William R Swindell, Krzysztof Bojanowski, Ratan K Chaudhuri

Eur J Dermatol· October 2020

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