Publications by authors named "Walid Mahfouf"

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Metabolism-based scoring of cutaneous squamous cell carcinoma to predict tumour features and responses to treatment with dihydroorotate dehydrogenase inhibitors.
Lea Dousset, Ferial Khalife, Domitille Chalopin-Fillot, Benjamin Dartigues, Fatima Naji, Walid Mahfouf

Br J Dermatol· October 2025

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Immune signatures across different stages of cutaneous squamous cell carcinoma.
Laure Favot-Laforge, Elodie Muzotte, Walid Mahfouf, Jerome Rambert, Muriel Cario

J Dermatol Sci· May 2025

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Energy metabolism rewiring following acute UVB irradiation is largely dependent on nuclear DNA damage.
Léa Dousset, Walid Mahfouf, Hadi Younes, Hala Fatrouni, Corinne Faucheux

Free Radic Biol Med· February 2025

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Xeroderma Pigmentosum Type C Primary Skin Fibroblasts Overexpress HGF and Promote Squamous Cell Carcinoma Invasion in the Absence of Genotoxic Stress.
Sahar Al-Qaraghuli, Yannick Gache, Maria Goncalves-Maia, Damien Alcor, Elodie Muzotte, Walid Mahfouf

Cancers (Basel)· September 2024

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Proteome characterization of XPC-deficient melanocytes generated by CRISPR-Cas9 technology reveals alteration in the expression of several hundred proteins.
Muriel Cario, Julie Scalia, Walid Mahfouf, Elodie Muzotte, Vincent Michaud

J Dermatol Sci· May 2024

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Evaluation of mitochondrial stress following ultraviolet radiation and 5G radiofrequency field exposure in human skin cells.
Lorenza Patrignoni, Annabelle Hurtier, Rosa Orlacchio, Alexandre Joushomme, Florence Poulletier de Gannes, Walid Mahfouf

Bioelectromagnetics· April 2024

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The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.
Julie Lavie, Claude Lalou, Walid Mahfouf, Jean-William Dupuy, Aurélie Lacaule

Cell Rep· June 2023

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Rewiring Lipid Metabolism by Targeting PCSK9 and HMGCR to Treat Liver Cancer.
Malak Alannan, Véronique Trézéguet, Nivea Dias Amoêdo, Rodrigue Rossignol, Walid Mahfouf

Cancers (Basel)· December 2022

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Targeting Human Lung Adenocarcinoma with a Suppressor of Mitochondrial Superoxide Production.
Nivea Dias Amoedo, Laetitia Dard, Saharnaz Sarlak, Walid Mahfouf, Wendy Blanchard

Antioxid Redox Signal· November 2020

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Xeroderma Pigmentosum C (XPC) Mutations in Primary Fibroblasts Impair Base Excision Repair Pathway and Increase Oxidative DNA Damage.
Nour Fayyad, Farah Kobaisi, David Beal, Walid Mahfouf, Cécile Ged

Front Genet· November 2020

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Trisk 95 as a novel skin mirror for normal and diabetic systemic glucose level.
Nsrein Ali, Hamid Reza Rezvani, Diana Motei, Sufyan Suleman, Walid Mahfouf

Sci Rep· July 2020

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Loss of Epidermal HIF-1α Blocks UVB-Induced Tumorigenesis by Affecting DNA Repair Capacity and Oxidative Stress.
Walid Mahfouf, Mohsen Hosseini, Elodie Muzotte, Martin Serrano-Sanchez, Lea Dousset

J Invest Dermatol· September 2019

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UVB-induced DHODH upregulation, which is driven by STAT3, is a promising target for chemoprevention and combination therapy of photocarcinogenesis.
Mohsen Hosseini, Léa Dousset, Pauline Michon, Walid Mahfouf, Elodie Muzotte

Oncogenesis· September 2019

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Energy Metabolism Rewiring Precedes UVB-Induced Primary Skin Tumor Formation.
Mohsen Hosseini, Léa Dousset, Walid Mahfouf, Martin Serrano-Sanchez, Isabelle Redonnet-Vernhet

Cell Rep· June 2018

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NADPH Oxidase-1 Plays a Key Role in Keratinocyte Responses to UV Radiation and UVB-Induced Skin Carcinogenesis.
Houssam Raad, Martin Serrano-Sanchez, Ghida Harfouche, Walid Mahfouf, Doriane Bortolotto

J Invest Dermatol· June 2017

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Correction: Inhibition of p38 MAPK Signaling Augments Skin Tumorigenesis via NOX2 Driven ROS Generation.
Liang Liu, Hamid Reza Rezvani, Jung Ho Back, Mohsen Hosseini, Xiuwei Tang, Walid Mahfouf

PLoS One· February 2017

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Premature skin aging features rescued by inhibition of NADPH oxidase activity in XPC-deficient mice.
Mohsen Hosseini, Walid Mahfouf, Martin Serrano-Sanchez, Houssam Raad, Ghida Harfouche

J Invest Dermatol· April 2015

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Inhibition of p38 MAPK signaling augments skin tumorigenesis via NOX2 driven ROS generation.
Liang Liu, Hamid Reza Rezvani, Jung Ho Back, Mohsen Hosseini, Xiuwei Tang, Walid Mahfouf

PLoS One· December 2014

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Rheb regulates mitophagy induced by mitochondrial energetic status.
Su Melser, Etienne Hébert Chatelain, Julie Lavie, Walid Mahfouf, Caroline Jose

Cell Metab· May 2013

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XPC silencing in normal human keratinocytes triggers metabolic alterations that drive the formation of squamous cell carcinomas.
Hamid Reza Rezvani, Arianna L Kim, Rodrigue Rossignol, Nsrein Ali, Meaghan Daly, Walid Mahfouf

J Clin Invest· January 2011

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Hypoxia-inducible factor-1alpha regulates the expression of nucleotide excision repair proteins in keratinocytes.
Hamid Reza Rezvani, Walid Mahfouf, Nsrein Ali, Cecile Chemin, Cecile Ged

Nucleic Acids Res· January 2010

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The necrotic signal induced by mycophenolic acid overcomes apoptosis-resistance in tumor cells.
Gwendaline Guidicelli, Benjamin Chaigne-Delalande, Marie-Sarah Dilhuydy, Benoît Pinson, Walid Mahfouf

PLoS One· September 2009

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The immunosuppressor mycophenolic acid kills activated lymphocytes by inducing a nonclassical actin-dependent necrotic signal.
Benjamin Chaigne-Delalande, Gwendaline Guidicelli, Lionel Couzi, Pierre Merville, Walid Mahfouf

J Immunol· December 2008

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