Publications by authors named "Walter Elger"

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A prodrug design for improved oral absorption and reduced hepatic interaction.
Gulzar Ahmed, Walter Elger, Frederick Meece, Hareesh B Nair, Birgitt Schneider

Bioorg Med Chem· October 2017

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Synthesis and biological evaluation of 11' imidazolyl antiprogestins and mesoprogestins.
Klaus Nickisch, Walter Elger, Bindu Santhamma, Robert Garfield, Zachary Killeen

Steroids· December 2014

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Synthesis and biological evaluation of partially fluorinated antiprogestins and mesoprogestins.
Klaus Nickisch, Walter Elger, James Cessac, Narkunan Kesavaram, Baishakhi Das

Steroids· February 2013

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Structure-based design, synthesis and in vitro characterization of potent 17beta-hydroxysteroid dehydrogenase type 1 inhibitors based on 2-substitutions of estrone and D-homo-estrone.
Gabriele Möller, Dominga Deluca, Christian Gege, Andrea Rosinus, Dorota Kowalik, Walter Elger

Bioorg Med Chem Lett· December 2009

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Role of nonhuman primate models in the discovery and clinical development of selective progesterone receptor modulators (SPRMs).
Kristof Chwalisz, Ramesh Garg, Robert Brenner, Ov Slayden, Craig Winkel, Walter Elger

Reprod Biol Endocrinol· May 2008

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A randomized, controlled trial of asoprisnil, a novel selective progesterone receptor modulator, in women with uterine leiomyomata.
Kristof Chwalisz, Lois Larsen, Cynthia Mattia-Goldberg, Anthony Edmonds, Walter Elger

Fertil Steril· June 2007

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Inhibitory effects of fluorine-substituted estrogens on the activity of 17beta-hydroxysteroid dehydrogenases.
Dominga Deluca, Gabriele Möller, Andrea Rosinus, Walter Elger, Alexander Hillisch

Mol Cell Endocrinol· March 2006

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Selective progesterone receptor modulator development and use in the treatment of leiomyomata and endometriosis.
Kristof Chwalisz, Maria Claudia Perez, Deborah Demanno, Craig Winkel, Gerd Schubert, Walter Elger

Endocr Rev· May 2005

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The effects of 1-month administration of asoprisnil (J867), a selective progesterone receptor modulator, in healthy premenopausal women.
Kristof Chwalisz, Walter Elger, Therese Stickler, Cynthia Mattia-Goldberg, Lois Larsen

Hum Reprod· April 2005

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Discovery, chemistry, and reproductive pharmacology of asoprisnil and related 11beta-benzaldoxime substituted selective progesterone receptor modulators (SPRMs).
Gerd Schubert, Walter Elger, Günter Kaufmann, Birgitt Schneider, Gudrun Reddersen

Semin Reprod Med· February 2005

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Estrone sulfate is a major source of local estrogen formation in human bone.
Mischa Muir, Gabriela Romalo, Lutz Wolf, Walter Elger, Hans-Udo Schweikert

J Clin Endocrinol Metab· September 2004

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Dissecting physiological roles of estrogen receptor alpha and beta with potent selective ligands from structure-based design.
Alexander Hillisch, Olaf Peters, Dirk Kosemund, Gerd Müller, Alexander Walter, Walter Elger

Mol Endocrinol· July 2004

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The significance of the 20-carbonyl group of progesterone in steroid receptor binding: a molecular dynamics and structure-based ligand design study.
Alexander Hillisch, Johannes von Langen, Bernd Menzenbach, Peter Droescher, Günter Kaufmann, Walter Elger

Steroids· November 2003

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Conception and pharmacodynamic profile of drospirenone.
Walter Elger, Sybille Beier, Kunhard Pollow, Robert Garfield, Shao Qing Shi

Steroids· November 2003

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Asoprisnil (J867): a selective progesterone receptor modulator for gynecological therapy.
Deborah DeManno, Walter Elger, Ramesh Garg, Ronald Lee, Birgitt Schneider

Steroids· November 2003

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Effect of estradiol sulfamate (ES-J995) on affinity of hemoglobin for oxygen, cardiovascular function and acid-base balance in ovariectomized rats.
Kathrin Bauer, Walter Elger, Birgitt Schneider, Elisabeth Krahl, Reinhard Bauer

Exp Toxicol Pathol· November 2003

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Effects of estradiol and estradiol sulfamate on the liver of ovariectomized or ovariectomized and hypophysectomized rats.
Lena Sahlin, Walter Elger, Annemarie Hedden, Monica Lindberg, Gudrun Reddersen

J Steroid Biochem Mol Biol· April 2002

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Selective progesterone receptor modulators (SPRMs): a novel therapeutic concept in endometriosis.
Kristof Chwalisz, Ramesh Garg, Robert M Brenner, Gerd Schubert, Walter Elger

Ann N Y Acad Sci· March 2002

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