Publications by authors named "Wan-Wan Lin"

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Decoding SIGLEC12 in Bladder Cancer: In Silico Profiling of Expression, Tumor-Immune Interactions, and Prognostic Impact.
Varsha Rathore, Wan-Wan Lin

Medicina (Kaunas)· October 2025

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CASK promotes prostate cancer progression via kinase-dependent activation of AKT.
Varsha Rathore, Ching-Yuan Cheng, Shao-Peng Chen, Chia-Yee Lin, Chuang-Rung Chang, Wan-Wan Lin

Int J Biol Macromol· June 2025

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Aloe polysaccharide promotes keratinocyte proliferation, migration, and differentiation by upregulating the EGFR/PKC-dependent signaling pathways.
Ching-Yuan Cheng, Shao-Hsuan Hsu, Uvarani Chokkalingam, Yang-Shia Dai, Pei-Chun Shih, Wan-Wan Lin

Sci Rep· March 2025

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Methylglyoxal: A Key Factor for Diabetic Retinopathy and Its Effects on Retinal Damage.
Vladlen Klochkov, Chi-Ming Chan, Wan-Wan Lin

Biomedicines· November 2024

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NLRX1 Inhibits LPS-Induced Microglial Death via Inducing p62-Dependent HO-1 Expression, Inhibiting MLKL and Activating PARP-1.
Yu-Ling Huang, Duen-Yi Huang, Vladlen Klochkov, Chi-Ming Chan, Yuan-Shen Chen, Wan-Wan Lin

Antioxidants (Basel)· April 2024

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CASK Mediates Oxidative Stress-Induced Microglial Apoptosis-Inducing Factor-Independent Parthanatos Cell Death via Promoting PARP-1 Hyperactivation and Mitochondrial Dysfunction.
Keith Jun Hao Cheong, Duen-Yi Huang, Ponarulselvam Sekar, Rou Jhen Chen, Irene Han-Juo Cheng, Wan-Wan Lin

Antioxidants (Basel)· March 2024

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Spatiotemporal roles of AMPK in PARP-1- and autophagy-dependent retinal pigment epithelial cell death caused by UVA.
Anthony Yan-Tang Wu, Ponarulselvam Sekar, Duen-Yi Huang, Shu-Hao Hsu, Chi-Ming Chan, Wan-Wan Lin

J Biomed Sci· November 2023

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Metformin inhibits methylglyoxal-induced retinal pigment epithelial cell death and retinopathy via AMPK-dependent mechanisms: Reversing mitochondrial dysfunction and upregulating glyoxalase 1.
Ponarulselvam Sekar, George Hsiao, Shu-Hao Hsu, Duen-Yi Huang, Wan-Wan Lin

Redox Biol· August 2023

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Epigenetic upregulation of spleen tyrosine kinase in cancer cells through p53-dependent downregulation of DNA methyltransferase.
Duen-Yi Huang, Shang-Te Lu, Yuan-Shen Chen, Ching-Yuan Cheng, Wan-Wan Lin

Exp Cell Res· April 2023

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P2X7 Is Involved in the Mouse Retinal Degeneration via the Coordinated Actions in Different Retinal Cell Types.
Ponarulselvam Sekar, George Hsiao, Yuan-Shen Chen, Wan-Wan Lin, Chi-Ming Chan

Antioxidants (Basel)· January 2023

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Pan-Caspase Inhibitor zVAD Induces Necroptotic and Autophagic Cell Death in TLR3/4-Stimulated Macrophages.
Yuan-Shen Chen, Wei-Chu Chuang, Hsiu-Ni Kung, Ching-Yuan Cheng, Duen-Yi Huang, Wan-Wan Lin

Mol Cells· April 2022

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P2X7 Activation Enhances Lipid Accumulation During Adipocytes Differentiation Through Suppressing the Expression of Sirtuin-3, Sirtuin-5, and Browning Genes.
Chien-Hsieh Chiang, Ching-Yuan Cheng, Yi-Ting Lien, Kuo-Chin Huang, Wan-Wan Lin

Front Pharmacol· April 2022

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Decoy receptor 3 is involved in epidermal keratinocyte commitment to terminal differentiation via EGFR and PKC activation.
Nan-Lin Wu, Duen-Yi Huang, Shie-Liang Hsieh, Yang-Shia Dai, Wan-Wan Lin

Exp Mol Med· April 2022

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Blimp-1 Upregulation by Multiple Ligands EGFR Transactivation Inhibits Cell Migration in Keratinocytes and Squamous Cell Carcinoma.
Hyemin Lee, Duen-Yi Huang, Hua-Ching Chang, Chia-Yee Lin, Wan-Yu Ren, Wan-Wan Lin

Front Pharmacol· February 2022

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PARP-1 regulates inflammasome activity by poly-ADP-ribosylation of NLRP3 and interaction with TXNIP in primary macrophages.
Ling-Ya Chiu, Duen-Yi Huang, Wan-Wan Lin

Cell Mol Life Sci· January 2022

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Decoy Receptor 3 Inhibits Monosodium Urate-Induced NLRP3 Inflammasome Activation Reduction of Reactive Oxygen Species Production and Lysosomal Rupture.
Yi-Gen Pan, Ming-Ting Huang, Ponarulselvam Sekar, Duen-Yi Huang, Wan-Wan Lin

Front Immunol· October 2021

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Incorporating Post-Cessation Weight-Control Coaching into Smoking Cessation Therapy to Reduce Type 2 Diabetes Risk.
Chien-Hsieh Chiang, Yi-Han Sheu, Fei-Ran Guo, Wan-Wan Lin, Guan-Ru Chen

Nutrients· September 2021

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PARP-1 involves in UVB-induced inflammatory response in keratinocytes and skin injury via regulation of ROS-dependent EGFR transactivation and p38 signaling.
Ling-Ya Chiu, Nan-Lin Wu, Chi-Feng Hung, Péter Bai, Yang-Shia Dai, Wan-Wan Lin

FASEB J· March 2021

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Multiresolution Imaging Using Bioluminescence Resonance Energy Transfer Identifies Distinct Biodistribution Profiles of Extracellular Vesicles and Exomeres with Redirected Tropism.
Anthony Yan-Tang Wu, Yun-Chieh Sung, Yen-Ju Chen, Steven Ting-Yu Chou, Vanessa Guo, Alan Ling Yang, Wan-Wan Lin

Adv Sci (Weinh)· October 2020

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Different Effects of Metformin and A769662 on Sodium Iodate-Induced Cytotoxicity in Retinal Pigment Epithelial Cells: Distinct Actions on Mitochondrial Fission and Respiration.
Chi-Ming Chan, Ponarulselvam Sekar, Duen-Yi Huang, Shu-Hao Hsu, Wan-Wan Lin

Antioxidants (Basel)· October 2020

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Galectin-3 regulates UVB-induced inflammation in skin.
Jen-Yu Wang, Po-Hsuan Lu, Wan-Wan Lin, Yu-Hsuan Wei, Ling-Ya Chiu, Nan-Lin Wu

J Dermatol Sci· May 2020

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Synergistic Anti-Tumour Effect of Syk Inhibitor and Olaparib in Squamous Cell Carcinoma: Roles of Syk in EGFR Signalling and PARP1 Activation.
Duen-Yi Huang, Wei-Yu Chen, Chi-Long Chen, Nan-Lin Wu, Wan-Wan Lin

Cancers (Basel)· February 2020

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Correction to: Reactive oxygen species-dependent mitochondrial dynamics and autophagy confer protective effects in retinal pigment epithelial cells against sodium iodate-induced cell death.
Chi-Ming Chan, Duen-Yi Huang, Ponarulselvam Sekar, Shu-Hao Hsu, Wan-Wan Lin

J Biomed Sci· September 2019

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Chronic Viral Hepatitis Signifies the Association of Premixed Insulin Analogues with Liver Cancer Risks: A Nationwide Population-Based Study.
Chien-Hsieh Chiang, Chia-Sheng Kuo, Wan-Wan Lin, Jun-Han Su, Jin-De Chen

Int J Environ Res Public Health· June 2019

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Reactive oxygen species-dependent mitochondrial dynamics and autophagy confer protective effects in retinal pigment epithelial cells against sodium iodate-induced cell death.
Chi-Ming Chan, Duen-Yi Huang, Ponarulselvam Sekar, Shu-Hao Hsu, Wan-Wan Lin

J Biomed Sci· May 2019

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