Publications by authors named "Wangyang Tu"

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Identification of Novel 2‑(Azetidin-3-ylamino)-nicotinamide Derivatives as Potent KRAS::SOS1 Inhibitors.
Dongsheng Li, Qing Xie, Maozhi Yang, Kang Sun, Shujuan Jiang, Wangyang Tu

ACS Med Chem Lett· August 2025

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Discovery of orally bioavailable phosphonate prodrugs of potent ENPP1 inhibitors for cancer treatment.
Shanyun Gao, Yingjie Hou, Yanxiao Xu, Jingjing Li, Chaobo Zhang, Wangyang Tu

Eur J Med Chem· December 2024

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Discovery of Pyrazolo[1,5,4-de]quinoxalin-2(3)-one Derivatives as Highly Potent and Selective PARP1 Inhibitors.
Shanyun Gao, Yingjie Hou, Yanxiao Xu, Jingjing Li, Chaobo Zhang, Wangyang Tu

J Med Chem· December 2024

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Lead Identification of Novel Naphthyridine Derivatives as Potent SOS1 Inhibitors.
Dongsheng Li, Qing Xie, Maozhi Yang, Yalei Cai, Kang Sun, Wangyang Tu

ACS Med Chem Lett· June 2024

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Discovery of Highly Potent and Selective IRAK1 Degraders to Probe Scaffolding Functions of IRAK1 in ABC DLBCL.
Liqiang Fu, Jing Zhang, Bin Shen, Linglong Kong, Yingtao Liu, Wangyang Tu

J Med Chem· August 2021

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Discovery of Hydroxyamidine Derivatives as Highly Potent, Selective Indoleamine-2,3-dioxygenase 1 Inhibitors.
Fangfang Jin, Qiyue Hu, Hongbo Fei, Hejun Lv, Shenglan Wang, Wangyang Tu

ACS Med Chem Lett· February 2021

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Discovery of Imidazoisoindole Derivatives as Highly Potent and Orally Active Indoleamine-2,3-dioxygenase Inhibitors.
Wangyang Tu, Fanglong Yang, Guoji Xu, Jiangtao Chi, Zhiwei Liu

ACS Med Chem Lett· June 2019

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Structure-based design and synthesis of bicyclic fused-pyridines as MEK inhibitors.
Hejun Lu, Wangyang Tu, Hongbo Fei, Guoji Xu, Qiyue Hu

Bioorg Med Chem Lett· June 2014

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Synthesis and biological evaluation of cyclopentyl-triazolol-pyrimidine (CPTP) based P2Y12 antagonists.
Wangyang Tu, Jiang Fan, Haitang Zhang, Guoji Xu, Zhiwei Liu

Bioorg Med Chem Lett· January 2014

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Total synthesis of neopeltolide and analogs.
Yubo Cui, Wangyang Tu, Paul E Floreancig

Tetrahedron· June 2010

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Oxidative carbocation formation in macrocycles: synthesis of the neopeltolide macrocycle.
Wangyang Tu, Paul E Floreancig

Angew Chem Int Ed Engl· July 2009

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Diastereoselective tetrahydropyrone synthesis through transition-metal-free oxidative carbon-hydrogen bond activation.
Wangyang Tu, Lei Liu, Paul E Floreancig

Angew Chem Int Ed Engl· July 2008

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Intramolecular electron transfer initiated cation and radical formation through carbon-carbon bond activation.
Wangyang Tu, Paul E Floreancig

Org Lett· June 2007

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