Publications by authors named "Wankyu Kim"

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Cathepsin L as a dual-target to mitigate muscle wasting while enhancing anti-tumor efficacy of anti-PD-L1.
Se-Young Park, Kyuwon Son, Jiwoo Kim, Kyeongah Kim, Sungmin Joo, Bomi Kim, Wankyu Kim

Nat Commun· November 2025

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Dual inhibitors of P-glycoprotein and breast cancer resistance protein for overcoming the blood-brain barrier: in silico discovery and preclinical evaluation.
Jiyeon Kang, Yukyeong Paik, Hwa Jeong Ryu, Jaeok Lee, Irin Shin, Jihye Kim, Wankyu Kim

Arch Pharm Res· October 2025

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Application of 3D atom pair map in an attention model for enhanced drug virtual screening.
Gina Ryu, Wankyu Kim

J Cheminform· May 2025

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Molecular Clustering of Metabolic Dysfunction-Associated Steatotic Liver Disease Based on Transcriptome Analysis.
Gina Ryu, Eileen Laurel Yoon, Wankyu Kim, Dae Won Jun

Diagnostics (Basel)· January 2025

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5-aminosalicylic acid suppresses osteoarthritis through the OSCAR-PPARγ axis.
Jihee Kim, Gina Ryu, Jeongmin Seo, Miyeon Go, Gyungmin Kim, Suwon Kim, Han Sung Kim, Wankyu Kim

Nat Commun· February 2024

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NecroX Improves Polyhexamethylene Guanidine-induced Lung Injury by Regulating Mitochondrial Oxidative Stress and Endoplasmic Reticulum Stress.
Jae Seok Jeong, Yeogha Yoon, Wankyu Kim, Hee Jung Kim, Hae Jin Park, So Ri Kim, Soon Ha Kim, Dong Im Kim

Am J Respir Cell Mol Biol· July 2023

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BEAR: A Novel Virtual Screening Method Based on Large-Scale Bioactivity Data.
Yeajee Kwon, Sera Park, Jaeok Lee, Jiyeon Kang, Hwa Jeong Lee, Wankyu Kim

J Chem Inf Model· March 2023

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SARS-CoV-2 infection in severe asthma is associated with worsening of COVID-19 through respiratory NLRP3 inflammasome activation.
Jae Seok Jeong, Jin Young Choi, Jong Seung Kim, Seong Ok Park, Wankyu Kim, Doo Hwan Kim, Jung Mo Kim

Allergy· January 2023

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Targeting Na-H exchanger 1 overcomes nuclear factor kappa B-mediated tumor resistance to radiotherapy.
Arang Son, Seoyeong Kang, Suha Choi, Sung-Won Shin, Yeeun Kim, Wankyu Kim

Neoplasia· January 2023

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Discovery of dipeptidyl peptidase-4 inhibitor specific biomarker in non-alcoholic fatty liver disease mouse models using modified basket trial.
Ju Hee Oh, Dae Won Jun, Hye Young Kim, Seung Min Lee, Eileen L Yoon, Wankyu Kim, Hyunsung Kim

Clin Mol Hepatol· July 2022

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Comprehensive Survey of Recent Drug Discovery Using Deep Learning.
Jintae Kim, Sera Park, Dongbo Min, Wankyu Kim

Int J Mol Sci· September 2021

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Circulating Small Extracellular Vesicles Activate TYRO3 to Drive Cancer Metastasis and Chemoresistance.
Miso Park, Ji Won Kim, Kyu Min Kim, Seungmin Kang, Wankyu Kim, Jin-Ki Kim, Yeonji Kim

Cancer Res· July 2021

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Correction to: Connectivity map-based drug repositioning of bortezomib to reverse the metastatic effect of GALNT14 in lung cancer.
Ok-Seon Kwon, Haeseung Lee, Hyeon-Joon Kong, Eun-Ji Kwon, Ji Eun Park, Mirang Kim, Wankyu Kim

Oncogene· March 2021

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Crosstalk between YAP and TGFβ regulates SERPINE1 expression in mesenchymal lung cancer cells.
Hyeon-Joon Kong, Eun-Ji Kwon, Ok-Seon Kwon, Haeseung Lee, Jeong-Yun Choi, Yung-Jeong Kim, Wankyu Kim

Int J Oncol· January 2021

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Safe scarless cassette-free selection of genome-edited human pluripotent stem cells using temporary drug resistance.
Keun-Tae Kim, Ju-Chan Park, Hyeon-Ki Jang, Haeseung Lee, Seokwoo Park, Jumee Kim, Wankyu Kim

Biomaterials· December 2020

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Naa20, the catalytic subunit of NatB complex, contributes to hepatocellular carcinoma by regulating the LKB1-AMPK-mTOR axis.
Taek-Yeol Jung, Jae-Eun Ryu, Mi-Mi Jang, Soh-Yeon Lee, Gyu-Rin Jin, Chan-Woo Kim, Hyelee Kim, EungHan Kim, Wankyu Kim, TaeSoo Kim, Hyun-Seok Kim

Exp Mol Med· November 2020

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Systematic identification of a nuclear receptor-enriched predictive signature for erastin-induced ferroptosis.
Ok-Seon Kwon, Eun-Ji Kwon, Hyeon-Joon Kong, Jeong-Yoon Choi, Yun-Jeong Kim, Wankyu Kim

Redox Biol· October 2020

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Identification of MYC as an antinecroptotic protein that stifles RIPK1-RIPK3 complex formation.
Daehyeon Seong, Manhyung Jeong, Jinho Seo, Ji-Yoon Lee, Chi Hyun Hwang, Hye-Jung Kim, Hwa-Ryeon Kim, Seung Jun Kim, Wankyu Kim

Proc Natl Acad Sci U S A· August 2020

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Osteoclast-associated receptor blockade prevents articular cartilage destruction via chondrocyte apoptosis regulation.
Doo Ri Park, Jihee Kim, Gyeong Min Kim, Haeseung Lee, Minhee Kim, Han-Sung Kim, Wankyu Kim

Nat Commun· August 2020

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Connectivity map-based drug repositioning of bortezomib to reverse the metastatic effect of GALNT14 in lung cancer.
Ok-Seon Kwon, Haeseung Lee, Hyeon-Joon Kong, Eun-Ji Kwon, Ji Eun Park, Mirang Kim, Wankyu Kim

Oncogene· June 2020

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MiR-4435 is an UQCRB-related circulating miRNA in human colorectal cancer.
Ji Won Hong, Jung Min Kim, Jeong Eun Kim, Hee Cho, Dasol Kim, Wankyu Kim

Sci Rep· February 2020

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In silico drug repositioning: from large-scale transcriptome data to therapeutics.
Ok-Seon Kwon, Wankyu Kim, Hyuk-Jin Cha, Haeseung Lee

Arch Pharm Res· October 2019

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Comparison of Target Features for Predicting Drug-Target Interactions by Deep Neural Network Based on Large-Scale Drug-Induced Transcriptome Data.
Hanbi Lee, Wankyu Kim

Pharmaceutics· August 2019

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Structure-Activity Relationship Analysis of YM155 for Inducing Selective Cell Death of Human Pluripotent Stem Cells.
Young-Hyun Go, Changjin Lim, Ho-Chang Jeong, Ok-Seon Kwon, Sungkyun Chung, Wankyu Kim, Seok-Ho Kim

Front Chem· May 2019

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CSgator: an integrated web platform for compound set analysis.
Sera Park, Yeajee Kwon, Hyesoo Jung, Sukyung Jang, Haeseung Lee, Wankyu Kim

J Cheminform· March 2019

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