Publications by authors named "Wanzhen Yang"

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Lead Optimization and Target Identification of Carboline Antifungal Agents.
Jingsheng Lin, Wanzhen Yang, Jiayun Xin, Hongxuan Cao, Ji Yang

J Med Chem· June 2025

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Microfibrillar-associated protein-2 facilitates aggressive progression of oral squamous cell carcinoma cells through Kelch-like E3 ubiquitin ligase-associated protein 1/nuclear factor erythroid 2-related factor 2 signaling pathway.
Wanzhen Yang, Junyi Tu, Kaixi Dai, Kemin Jia

Cytojournal· June 2025

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Discovery of New Pyrazolone Carbothioamide Derivatives as Potent Antifungal Agents for the Treatment of Candidiasis and Cryptococcosis.
Tingting Liang, Jie Tu, Qianqian He, Piaopiao Zou, Wanzhen Yang

J Med Chem· April 2025

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Discovery of new fungal jumonji H3K27 demethylase inhibitors for the treatment of Cryptococcus neoformans and Candida auris infections.
Xin Liu, Wang Li, Yang Liu, Xiaoqing Wang, Qiao Shi, Wanzhen Yang

Eur J Med Chem· January 2025

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Lanosterol 14α-Demethylase (CYP51)/Heat Shock Protein 90 (Hsp90) Dual Inhibitors for the Treatment of Invasive Candidiasis.
Mingming Zhang, Wanzhen Yang, Na Liu, Jie Tu, Jingsheng Lin

J Med Chem· January 2025

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Discovery of New Tricyclic Oxime Sampangine Derivatives as Potent Antifungal Agents for the Treatment of Cryptococcosis and Candidiasis.
Wanzhen Yang, Ruxiong Liu, Zhuang Li, Jie Tu, Dongjian Xu

J Med Chem· March 2024

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Discovery of a new chemical scaffold for the treatment of superbug infections.
Jie Tu, Tianbao Zhu, Qingwen Wang, Wanzhen Yang, Yahui Huang

Emerg Microbes Infect· December 2023

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Discovery of Pyrazolone Carbothioamide Derivatives as Inhibitors of the Pdr1-KIX Interaction for Combinational Treatment of Azole-Resistant Candidiasis.
Qingwen Wang, Jie Tu, Wanzhen Yang, Tingting Liang, Na Liu

J Med Chem· September 2023

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Controlling antifungal activity with light: Optical regulation of fungal ergosterol biosynthetic pathway with photo-responsive CYP51 inhibitors.
Zhuang Li, Na Liu, Wanzhen Yang, Jie Tu, Yahui Huang

Acta Pharm Sin B· July 2023

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Target- and prodrug-based design for fungal diseases and cancer-associated fungal infections.
Na Liu, Jie Tu, Yahui Huang, Wanzhen Yang, Qingwen Wang

Adv Drug Deliv Rev· June 2023

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Discovery of BRD4-HDAC Dual Inhibitors with Improved Fungal Selectivity and Potent Synergistic Antifungal Activity against Fluconazole-Resistant .
Zhuang Li, Yahui Huang, Jie Tu, Wanzhen Yang, Na Liu

J Med Chem· April 2023

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Small molecules for combating multidrug-resistant superbug infections.
Jie Tu, Na Liu, Yahui Huang, Wanzhen Yang, Chunquan Sheng

Acta Pharm Sin B· November 2022

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Jumonji Histone Demethylase Inhibitor JIB-04 as a Broad-Spectrum Antifungal Agent.
Tianyou Wang, Wanzhen Yang, Yun Liu, Wang Li, Yan Wang

ACS Infect Dis· July 2022

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Discovery of Novel Sertraline Derivatives as Potent Anti- Agents.
Wang Li, Zhaolin Yun, Changjin Ji, Jie Tu, Wanzhen Yang

J Med Chem· May 2022

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Role of Azole Drugs in Promoting Fungal Cell Autophagy Revealed by an NIR Fluorescence-Based Theranostic Probe.
Wanzhen Yang, Yanhui Zhang, Hao Teng, Na Liu, Chunquan Sheng

Anal Chem· May 2022

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Discovery of Piperidol Derivatives for Combinational Treatment of Azole-Resistant Candidiasis.
Wanzhen Yang, Jie Tu, Changjin Ji, Zhuang Li, Guiyan Han

ACS Infect Dis· March 2021

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[Status and further development of regulation for pesticide registration for Chinese medicinal materials].
Chao-Geng Lyu, Sheng Wang, Xia-Hong He, Lin He, Wan-Zhen Yang

Zhongguo Zhong Yao Za Zhi· October 2018

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Bioaccessibility and risk assessment of heavy metals, and analysis of arsenic speciation in .
Li Zhou, Sheng Wang, Qingxiu Hao, Liping Kang, Chuanzhi Kang, Jian Yang, Wanzhen Yang

Chin Med· July 2018

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Elucidation of Characteristic Sulfur-Fumigated Markers and Chemical Transformation Mechanism for Quality Control of Blume Using Metabolome and Sulfur Dioxide Residue Analysis.
Chuanzhi Kang, Dan Zhao, Liping Kang, Sheng Wang, Chaogeng Lv, Wanzhen Yang

Front Plant Sci· June 2018

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[Assessment of soil fertility for cultivation of Chinese herbal medicines].
Jing-Yi Jiang, Wan-Zhen Yang, Chuan-Zhi Kang, Ya-Hui Liu, Sheng Wang

Zhongguo Zhong Yao Za Zhi· February 2018

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[Sulfur dioxide limit standard and residues in Chinese medicinal materials].
Chuan-Zhi Kang, Wan-Zhen Yang, Ge Mo, Li Zhou, Jing-Yi Jiang, Ye Yang

Zhongguo Zhong Yao Za Zhi· January 2018

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[Quantitative analysis and stability of -hydroxybenzyl hydrogen sulfite in sulfur-fumigated Gastrodiae Rhizoma].
Chuan-Zhi Kang, Jing-Yi Jiang, Wan-Zhen Yang, Li Zhou, Chao-Geng Lv, Ye Yang

Zhongguo Zhong Yao Za Zhi· January 2018

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[Quality changes in Gastrodia Rhizoma of different origins and forms before and after sulfur fumigation].
Chuan-Zhi Kang, Wan-Zhen Yang, Li Zhou, Jing-Yi Jiang, Chao-Geng Lv, Ye Yang

Zhongguo Zhong Yao Za Zhi· January 2018

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[Changes of chemical compositions and sulfur dioxide residues of Gastrodiae Rhizoma with different storage times].
Chuan-Zhi Kang, Jing-Yi Jiang, Wan-Zhen Yang, Li Zhou, Chao-Geng Lv, Ye Yang

Zhongguo Zhong Yao Za Zhi· January 2018

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[Study on distribution of five heavy metal elements in different parts of Cordyceps sinensis by microwave digestion ICP-MS].
Li Zhou, Qing-Xiu Hao, Sheng Wang, Quan Yang, Chuan-Zhi Kang, Wan-Zhen Yang

Zhongguo Zhong Yao Za Zhi· August 2017

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