Publications by authors named "Warren Strittmatter"

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An Exploratory Phase IIa Study of the PPAR delta/gamma Agonist T3D-959 Assessing Metabolic and Cognitive Function in Subjects with Mild to Moderate Alzheimer's Disease.
Stanley Chamberlain, Hoda Gabriel, Warren Strittmatter, John Didsbury

J Alzheimers Dis· May 2021

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Inhibition of protein misfolding/aggregation using polyglutamine binding peptide QBP1 as a therapy for the polyglutamine diseases.
H Akiko Popiel, Toshihide Takeuchi, James R Burke, Warren J Strittmatter, Tatsushi Toda

Neurotherapeutics· July 2013

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Bathing the brain.
Warren J Strittmatter

J Clin Invest· March 2013

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The Aggregation Inhibitor Peptide QBP1 as a Therapeutic Molecule for the Polyglutamine Neurodegenerative Diseases.
H Akiko Popiel, James R Burke, Warren J Strittmatter, Shinya Oishi, Nobutaka Fujii

J Amino Acids· August 2012

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Alzheimer’s disease: the new promise.
Warren J Strittmatter

J Clin Invest· April 2012

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Medicine. Old drug, new hope for Alzheimer's disease.
Warren J Strittmatter

Science· March 2012

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Genome-wide scan of copy number variation in late-onset Alzheimer's disease.
Erin L Heinzen, Anna C Need, Kathleen M Hayden, Ornit Chiba-Falek, Allen D Roses, Warren J Strittmatter

J Alzheimers Dis· August 2010

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A genome-wide investigation of SNPs and CNVs in schizophrenia.
Anna C Need, Dongliang Ge, Michael E Weale, Jessica Maia, Sheng Feng, Warren J Strittmatter

PLoS Genet· February 2009

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Identification of chemical inhibitors to human tissue transglutaminase by screening existing drug libraries.
Thung-S Lai, Yusha Liu, Tim Tucker, Kurt R Daniel, David C Sane, Warren J Strittmatter

Chem Biol· September 2008

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Mortalin is regulated by APOE in hippocampus of AD patients and by human APOE in TR mice.
Cristina Osorio, Patrick M Sullivan, Dong Ning He, Brian E Mace, John F Ervin, Warren J Strittmatter

Neurobiol Aging· December 2007

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Optimization of a polyglutamine aggregation inhibitor peptide (QBP1) using a thioflavin T fluorescence assay.
Lora Hamuro, Guangtao Zhang, Timothy J Tucker, Christopher Self, Warren J Strittmatter

Assay Drug Dev Technol· October 2007

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High-fat/high-cholesterol diet promotes a S1P receptor-mediated antiapoptotic activity for VLDL.
Mirta Mihovilovic, Jennifer B Robinette, Robert M DeKroon, Patrick M Sullivan, Warren J Strittmatter

J Lipid Res· April 2007

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Apolipoprotein E alleles and sensorineural hearing loss.
Gwen O'Grady, Abee L Boyles, Marcy Speer, Frank DeRuyter, Warren Strittmatter

Int J Audiol· April 2007

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Phage display screening for peptides that inhibit polyglutamine aggregation.
Daniel J Kenan, Warren J Strittmatter, James R Burke

Methods Enzymol· November 2006

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APOE4-VLDL inhibits the HDL-activated phosphatidylinositol 3-kinase/Akt Pathway via the phosphoinositol phosphatase SHIP2.
Robert DeKroon, Jennifer B Robinette, Anita B Hjelmeland, Emma Wiggins, Morven Blackwell, Warren J Strittmatter

Circ Res· October 2006

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APOE2 allele increased in tardive dyskinesia.
Jonathan Halford, Gandis Mazeika, Susan Slifer, Marcy Speer, Ann M Saunders, Warren J Strittmatter

Mov Disord· April 2006

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Polyglutamine expansion inhibits respiration by increasing reactive oxygen species in isolated mitochondria.
Kasturi L Puranam, Guanghong Wu, Warren J Strittmatter, James R Burke

Biochem Biophys Res Commun· March 2006

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Apolipoprotein E and brain injury: implications for children.
James A Blackman, Gordon Worley, Warren J Strittmatter

Dev Med Child Neurol· January 2005

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Disruption of the toxic conformation of the expanded polyglutamine stretch leads to suppression of aggregate formation and cytotoxicity.
Helena A Popiel, Yoshitaka Nagai, Osamu Onodera, Takashi Inui, Nobuhiro Fujikake, Warren J Strittmatter

Biochem Biophys Res Commun· May 2004

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APOE genotype-specific differences in human and mouse macrophage nitric oxide production.
Carol A Colton, Leila K Needham, Candice Brown, Danielle Cook, Karima Rasheed, Warren J Strittmatter

J Neuroimmunol· February 2004

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ApoE genotype-specific inhibition of apoptosis.
Robert M DeKroon, Mirta Mihovilovic, Zoe V Goodger, Jennifer B Robinette, Patrick M Sullivan, Warren J Strittmatter

J Lipid Res· August 2003

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Prevention of polyglutamine oligomerization and neurodegeneration by the peptide inhibitor QBP1 in Drosophila.
Yoshitaka Nagai, Nobuhiro Fujikake, Katsuhito Ohno, Hiroyuki Higashiyama, Helena A Popiel, Warren J Strittmatter

Hum Mol Genet· June 2003

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In vitro effects of polyglutamine tracts on Ca2+-dependent depolarization of rat and human mitochondria: relevance to Huntington's disease.
Alexander V Panov, James R Burke, Warren J Strittmatter, J Timothy Greenamyre

Arch Biochem Biophys· February 2003

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Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.
Alexander V Panov, Claire-Anne Gutekunst, Blair R Leavitt, Michael R Hayden, James R Burke, Warren J Strittmatter

Nat Neurosci· August 2002

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Expanded polyglutamine stretches form an 'aggresome'.
Takayoshi Shimohata, Aki Sato, James R Burke, Warren J Strittmatter, Shoji Tsuji

Neurosci Lett· May 2002

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