Publications by authors named "Waseem Qasim"

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Base edited "universal" donor CAR T-cell strategies for acute myeloid leukaemia.
Renuka Kadirkamanathan, Christos Georgiadis, Arnold Kloos, Akshay Joshi, Annie Etuk, Waseem Qasim

Leukemia· December 2025

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Universal Base-Edited CAR7 T Cells for T-Cell Acute Lymphoblastic Leukemia.
Robert Chiesa, Christos Georgiadis, Hebatalla Rashed, Roland Preece, Prudence Hardefeldt, Waseem Qasim

N Engl J Med· December 2025

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Long-term outcomes of genome-edited "universal" CAR19 T cells for relapsed/refractory B-ALL at a single pediatric center.
Daniela Guardo, Avijeet Kumar Mishra, Hebatalla Rashed, Kimberly Gilmour, Stuart Adams, Waseem Qasim

Blood Adv· September 2025

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Clinical development of allogeneic chimeric antigen receptor αβ-T cells.
Christos Georgiadis, Roland Preece, Waseem Qasim

Mol Ther· June 2025

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Current landscape of vector safety and genotoxicity after hematopoietic stem or immune cell gene therapy.
Giorgio Ottaviano, Waseem Qasim

Leukemia· June 2025

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New models for the development of and access to CAR T-cell therapies for children and adolescents with cancer: an ACCELERATE multistakeholder analysis.
Andrew D J Pearson, Claudia Rossig, Crystal L Mackall, Nirali N Shah, André Baruchel, Waseem Qasim

Lancet Oncol· April 2025

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Safety and Diagnostic Utility of Brain Biopsy and Metagenomics in Decision-Making for Patients with Inborn Errors of Immunity (IEI) and Unexplained Neurological Manifestations.
Jesmeen Maimaris, Julia Payne, Adriel Roa-Bautista, Judith Breuer, Nathaniel Storey, Waseem Qasim

J Clin Immunol· April 2025

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Umbilical cord blood T cells can be isolated and enriched by CD62L selection for use in 'off the shelf' chimeric antigen receptor T-cell therapies to widen transplant options.
Christos Georgiadis, Lauren Nickolay, Farhatullah Syed, Hong Zhan, Soragia Athina Gkazi, Waseem Qasim

Haematologica· December 2024

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Base-Edited CAR7 T Cells for Relapsed T-Cell Acute Lymphoblastic Leukemia.
Robert Chiesa, Christos Georgiadis, Farhatullah Syed, Hong Zhan, Annie Etuk, Waseem Qasim

N Engl J Med· September 2023

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Genome Editing in Engineered T Cells for Cancer Immunotherapy.
Chiara Bonini, Aude G Chapuis, Michael Hudecek, Sonia Guedan, Chiara Magnani, Waseem Qasim

Hum Gene Ther· September 2023

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Non-osteopenic Bone Pathology After Allo-hematopoietic Stem Cell Transplantation in Patients with Inborn Errors of Immunity.
Zainab M Golwala, Nikita Gireesh Bhat, Jinhua Xu-Bayford, Tanja Stankova, Stuart Adams, Waseem Qasim

J Clin Immunol· July 2023

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Cytosine Deaminase Base Editing to Restore in Dystrophic Epidermolysis Bullosa Human: Murine Skin Model.
Gaetano Naso, Soragia Athina Gkazi, Christos Georgiadis, Vignesh Jayarajan, Joanna Jacków, Waseem Qasim

JID Innov· May 2023

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Genome-edited allogeneic donor "universal" chimeric antigen receptor T cells.
Waseem Qasim

Blood· February 2023

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Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia.
Giorgio Ottaviano, Christos Georgiadis, Soragia Athina Gkazi, Farhatullah Syed, Hong Zhan, Waseem Qasim

Sci Transl Med· October 2022

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Genome-Edited T Cell Therapies.
Giorgio Ottaviano, Waseem Qasim

Hematol Oncol Clin North Am· August 2022

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Base-edited CAR T cells for combinational therapy against T cell malignancies.
Christos Georgiadis, Jane Rasaiyaah, Soragia Athina Gkazi, Roland Preece, Aniekan Etuk, Waseem Qasim

Leukemia· December 2021

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FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency.
Ioanna A Rota, Adam E Handel, Stefano Maio, Fabian Klein, Fatima Dhalla, Waseem Qasim

Sci Adv· December 2021

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Genome editing of therapeutic T cells.
Waseem Qasim

Gene Genome Ed· December 2021

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Metformin hydrochloride entrapment in sorbitan monostearate for intestinal permeability enhancement and pharmacodynamics.
Omar Y Mady, Adam A Al-Shoubki, Ahmed A Donia, Waseem Qasim

Sci Rep· October 2021

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Ex vivo gene modification therapy for genetic skin diseases-recent advances in gene modification technologies and delivery.
Vignesh Jayarajan, Evangelia Kounatidou, Waseem Qasim, Wei-Li Di

Exp Dermatol· July 2021

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Outcome of Non-hematological Autoimmunity After Hematopoietic Cell Transplantation in Children with Primary Immunodeficiency.
Su Han Lum, Reem Elfeky, Federica R Achini, Adriana Margarit-Soler, Bianca Cinicola, Waseem Qasim

J Clin Immunol· January 2021

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The role of immunotherapy in relapse/refractory precursor-B acute lymphoblastic leukaemia: real-life UK/Ireland experience in children and young adults.
Giorgio Ottaviano, Susan Baird, Denise Bonney, Philip Connor, Michelle Cummins, Waseem Qasim

Br J Haematol· January 2021

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CRISPR-Mediated Base Conversion Allows Discriminatory Depletion of Endogenous T Cell Receptors for Enhanced Synthetic Immunity.
Roland Preece, Andrea Pavesi, Soragia Athina Gkazi, Kerstin A Stegmann, Christos Georgiadis, Waseem Qasim

Mol Ther Methods Clin Dev· December 2020

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Genome-edited, donor-derived allogeneic anti-CD19 chimeric antigen receptor T cells in paediatric and adult B-cell acute lymphoblastic leukaemia: results of two phase 1 studies.
Reuben Benjamin, Charlotte Graham, Deborah Yallop, Agnieszka Jozwik, Oana C Mirci-Danicar, Waseem Qasim

Lancet· December 2020

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