Publications by authors named "Wayne Fenton"

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Chaperonin-assisted protein folding: a chronologue.
Arthur L Horwich, Wayne A Fenton

Q Rev Biophys· February 2020

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Hsp110 mitigates α-synuclein pathology in vivo.
Yumiko V Taguchi, Erica L Gorenberg, Maria Nagy, Drake Thrasher, Wayne A Fenton

Proc Natl Acad Sci U S A· November 2019

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Transfer of pathogenic and nonpathogenic cytosolic proteins between spinal cord motor neurons in vivo in chimeric mice.
Eleanor V Thomas, Wayne A Fenton, James McGrath, Arthur L Horwich

Proc Natl Acad Sci U S A· April 2017

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Extended survival of misfolded G85R SOD1-linked ALS mice by transgenic expression of chaperone Hsp110.
Maria Nagy, Wayne A Fenton, Di Li, Krystyna Furtak, Arthur L Horwich

Proc Natl Acad Sci U S A· May 2016

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Unfolded DapA forms aggregates when diluted into free solution, confounding comparison with folding by the GroEL/GroES chaperonin system.
Andrew Ambrose, Wayne Fenton, Damian J Mason, Eli Chapman, Arthur L Horwich

FEBS Lett· February 2015

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Absence of lipofuscin in motor neurons of SOD1-linked ALS mice.
Urmi Bandyopadhyay, Maria Nagy, Wayne A Fenton, Arthur L Horwich

Proc Natl Acad Sci U S A· July 2014

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Production of RNA for transcriptomic analysis from mouse spinal cord motor neuron cell bodies by laser capture microdissection.
Urmi Bandyopadhyay, Wayne A Fenton, Arthur L Horwich, Maria Nagy

J Vis Exp· January 2014

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RNA-Seq profiling of spinal cord motor neurons from a presymptomatic SOD1 ALS mouse.
Urmi Bandyopadhyay, Justin Cotney, Maria Nagy, Sunghee Oh, Jing Leng, Wayne A Fenton

PLoS One· August 2013

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Structure and allostery of the chaperonin GroEL.
Helen R Saibil, Wayne A Fenton, Daniel K Clare, Arthur L Horwich

J Mol Biol· May 2013

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Molecular chaperone Hsp110 rescues a vesicle transport defect produced by an ALS-associated mutant SOD1 protein in squid axoplasm.
Yuyu Song, Maria Nagy, Weiming Ni, Navneet K Tyagi, Wayne A Fenton

Proc Natl Acad Sci U S A· April 2013

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Hydrogen-deuterium exchange in vivo to measure turnover of an ALS-associated mutant SOD1 protein in spinal cord of mice.
George W Farr, Zheng Ying, Wayne A Fenton, Arthur L Horwich

Protein Sci· October 2011

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Double mutant MBP refolds at same rate in free solution as inside the GroEL/GroES chaperonin chamber when aggregation in free solution is prevented.
Navneet K Tyagi, Wayne A Fenton, Ashok A Deniz, Arthur L Horwich

FEBS Lett· June 2011

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ATP-triggered ADP release from the asymmetric chaperonin GroEL/GroES/ADP7 is not the rate-limiting step of the GroEL/GroES reaction cycle.
Navneet K Tyagi, Wayne A Fenton, Arthur L Horwich

FEBS Lett· March 2010

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GroEL/GroES cycling: ATP binds to an open ring before substrate protein favoring protein binding and production of the native state.
Navneet K Tyagi, Wayne A Fenton, Arthur L Horwich

Proc Natl Acad Sci U S A· December 2009

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The GroEL/GroES cis cavity as a passive anti-aggregation device.
Arthur L Horwich, Adrian C Apetri, Wayne A Fenton

FEBS Lett· August 2009

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Chaperonin-mediated protein folding: using a central cavity to kinetically assist polypeptide chain folding.
Arthur L Horwich, Wayne A Fenton

Q Rev Biophys· May 2009

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Requirement for binding multiple ATPs to convert a GroEL ring to the folding-active state.
Eli Chapman, George W Farr, Wayne A Fenton, Steven M Johnson, Arthur L Horwich

Proc Natl Acad Sci U S A· December 2008

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Functional co-primary measures for clinical trials in schizophrenia: results from the MATRICS Psychometric and Standardization Study.
Michael F Green, Keith H Nuechterlein, Robert S Kern, Lyle E Baade, Wayne S Fenton

Am J Psychiatry· February 2008

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The MATRICS Consensus Cognitive Battery, part 2: co-norming and standardization.
Robert S Kern, Keith H Nuechterlein, Michael F Green, Lyle E Baade, Wayne S Fenton

Am J Psychiatry· February 2008

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The MATRICS Consensus Cognitive Battery, part 1: test selection, reliability, and validity.
Keith H Nuechterlein, Michael F Green, Robert S Kern, Lyle E Baade, Deanna M Barch, Wayne S Fenton

Am J Psychiatry· February 2008

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Two families of chaperonin: physiology and mechanism.
Arthur L Horwich, Wayne A Fenton, Eli Chapman, George W Farr

Annu Rev Cell Dev Biol· December 2007

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Folding trajectories of human dihydrofolate reductase inside the GroEL GroES chaperonin cavity and free in solution.
Reto Horst, Wayne A Fenton, S Walter Englander, Kurt Wüthrich, Arthur L Horwich

Proc Natl Acad Sci U S A· December 2007

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How should DSM-V criteria for schizophrenia include cognitive impairment?
Richard S E Keefe, Wayne S Fenton

Schizophr Bull· July 2007

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Perturbed ATPase activity and not "close confinement" of substrate in the cis cavity affects rates of folding by tail-multiplied GroEL.
George W Farr, Wayne A Fenton, Arthur L Horwich

Proc Natl Acad Sci U S A· March 2007

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