Publications by authors named "Wayne Hubbell"

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The lipid bilayer strengthens the cooperative network of membrane proteins.
Shaima MuhammedNazaar, Jiaqi Yao, Matthew R Necelis, Yein C Park, Zhongtian Shen, Wayne L Hubbell

Sci Adv· July 2025

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Lipid bilayer strengthens the cooperative network of membrane proteins.
Shaima Muhammednazaar, Jiaqi Yao, Matthew R Necelis, Yein C Park, Zhongtian Shen, Wayne L Hubbell

bioRxiv· December 2024

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A pressure-jump EPR system to monitor millisecond conformational exchange rates of spin-labeled proteins.
Julian D Grosskopf, Jason W Sidabras, Christian Altenbach, Jim R Anderson, Richard R Mett, Wayne L Hubbell

Protein Sci· December 2024

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Ligand efficacy modulates conformational dynamics of the µ-opioid receptor.
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Wayne L Hubbell

Nature· May 2024

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A pressure-jump EPR system to monitor millisecond conformational exchange rates of spin-labeled proteins.
Julian D Grosskopf, Jason W Sidabras, Christian Altenbach, Jim R Anderson, Richard R Mett, Wayne L Hubbell

bioRxiv· May 2024

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Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted / founder sensitivity to broadly neutralizing antibodies.
Durgadevi Parthasarathy, Karunakar Reddy Pothula, Kim-Marie A Dam, Sneha Ratnapriya, Héctor Cervera Benet, Wayne L Hubbell

bioRxiv· December 2023

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Membrane potential accelerates sugar uptake by stabilizing the outward facing conformation of the Na/glucose symporter vSGLT.
Farha Khan, Matthias Elgeti, Samuel Grandfield, Aviv Paz, Fiona B Naughton, Wayne L Hubbell

Nat Commun· November 2023

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A Highly Ordered Nitroxide Side Chain for Distance Mapping and Monitoring Slow Structural Fluctuations in Proteins.
Mengzhen Chen, Tamás Kálai, Duilio Cascio, Michael D Bridges, Julian P Whitelegge, Wayne L Hubbell

Appl Magn Reson· October 2023

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Conformational dynamics of the μ-opioid receptor determine ligand intrinsic efficacy.
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Wayne L Hubbell

bioRxiv· April 2023

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Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Zhi Yang, Kim-Marie A Dam, Michael D Bridges, Magnus A G Hoffmann, Andrew T DeLaitsch, Wayne L Hubbell

Nat Commun· February 2022

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Lipid bilayer induces contraction of the denatured state ensemble of a helical-bundle membrane protein.
Kristen A Gaffney, Ruiqiong Guo, Michael D Bridges, Shaima Muhammednazaar, Daoyang Chen, Wayne L Hubbell

Proc Natl Acad Sci U S A· January 2022

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DEER Analysis of GPCR Conformational Heterogeneity.
Matthias Elgeti, Wayne L Hubbell

Biomolecules· May 2021

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An Eight Amino Acid Segment Controls Oligomerization and Preferred Conformation of the two Non-visual Arrestins.
Qiuyan Chen, Ya Zhuo, Pankaj Sharma, Ivette Perez, Derek J Francis, Wayne L Hubbell

J Mol Biol· February 2021

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Viewing rare conformations of the β adrenergic receptor with pressure-resolved DEER spectroscopy.
Michael T Lerch, Rachel A Matt, Matthieu Masureel, Matthias Elgeti, Kaavya Krishna Kumar, Wayne L Hubbell

Proc Natl Acad Sci U S A· December 2020

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Synthetic nanobodies as angiotensin receptor blockers.
Conor McMahon, Dean P Staus, Laura M Wingler, Jialu Wang, Meredith A Skiba, Wayne L Hubbell

Proc Natl Acad Sci U S A· August 2020

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Resolving dynamics and function of transient states in single enzyme molecules.
Hugo Sanabria, Dmitro Rodnin, Katherina Hemmen, Thomas-Otavio Peulen, Suren Felekyan, Wayne Hubbell

Nat Commun· March 2020

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Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations.
Laura M Wingler, Matthias Elgeti, Daniel Hilger, Naomi R Latorraca, Michael T Lerch, Wayne L Hubbell

Cell· January 2019

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Conformational heterogeneity of the allosteric drug and metabolite (ADaM) site in AMP-activated protein kinase (AMPK).
Xin Gu, Michael D Bridges, Yan Yan, Parker W de Waal, X Edward Zhou, Wayne L Hubbell

J Biol Chem· November 2018

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Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Alexander F Kintzer, Evan M Green, Pawel K Dominik, Michael Bridges, Jean-Paul Armache, Wayne Hubbell

Proc Natl Acad Sci U S A· September 2018

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DEER Spectroscopy Measurements Reveal Multiple Conformations of HIV-1 SOSIP Envelopes that Show Similarities with Envelopes on Native Virions.
Beth M Stadtmueller, Michael D Bridges, Kim-Marie Dam, Michael T Lerch, Kathryn E Huey-Tubman, Wayne L Hubbell

Immunity· August 2018

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G- and G-coupled GPCRs show different modes of G-protein binding.
Ned Van Eps, Christian Altenbach, Lydia N Caro, Naomi R Latorraca, Scott A Hollingsworth, Wayne L Hubbell

Proc Natl Acad Sci U S A· March 2018

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Protonation state of glutamate 73 regulates the formation of a specific dimeric association of mVDAC1.
Lucie A Bergdoll, Michael T Lerch, John W Patrick, Kendrick Belardo, Christian Altenbach, Wayne L Hubbell

Proc Natl Acad Sci U S A· January 2018

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Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors.
X Edward Zhou, Yuanzheng He, Parker W de Waal, Xiang Gao, Yanyong Kang, Wayne L Hubbell

Cell· July 2017

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Conformational equilibria of light-activated rhodopsin in nanodiscs.
Ned Van Eps, Lydia N Caro, Takefumi Morizumi, Ana Karin Kusnetzow, Michal Szczepek, Wayne L Hubbell

Proc Natl Acad Sci U S A· April 2017

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A PII-Like Protein Regulated by Bicarbonate: Structural and Biochemical Studies of the Carboxysome-Associated CPII Protein.
Nicole M Wheatley, Kevin D Eden, Joanna Ngo, Justin S Rosinski, Michael R Sawaya, Wayne L Hubbell

J Mol Biol· October 2016

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