Publications by authors named "Wen-Jen Lin"

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ImmiR: A database of microRNAs associated with immune checkpoints and infiltrates.
Wen-Jen Lin, Yu-De Wang, Chia-Hsin Liu, Hsiu-Cheng Liu, Pei-Chun Shen, You-Zhe Lin

Comput Struct Biotechnol J· December 2025

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Advanced hyaluronic acid-modified niosomes for percutaneous delivery of resveratrol in the treatment of aged skin.
Wei Tsung Chen, Wen Jen Lin

Int J Biol Macromol· September 2025

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Ether-lipids accumulation promotes hepatocellular carcinoma progression linked to PPARα deficiency.
Pei-Yin Liao, Wen-Jen Lin, Pei-Chun Shen, Cian-Ru Yang, Ying-Chun Yu

J Biomed Sci· September 2025

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Peptide-Engineered Seliciclib Nanomedicine for Brain-Targeted Delivery and Neuroprotection.
Guan Zhen He, Wen Jen Lin

Int J Mol Sci· June 2025

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Structure of human MUTYH and functional profiling of cancer-associated variants reveal an allosteric network between its [4Fe-4S] cluster cofactor and active site required for DNA repair.
Carlos H Trasviña-Arenas, Upeksha C Dissanayake, Nikole Tamayo, Mohammad Hashemian, Wen-Jen Lin

Nat Commun· April 2025

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LipidFun: a database of lipid functions.
Wen-Jen Lin, Chia-Hsin Liu, Ming-Siang Huang, Pei-Chun Shen, Hsiu-Cheng Liu

Bioinformatics· March 2025

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LipidSigR: a R-based solution for integrated lipidomics data analysis and visualization.
Chia-Hsin Liu, Pei-Chun Shen, Meng-Hsin Tsai, Hsiu-Cheng Liu, Wen-Jen Lin

Bioinform Adv· March 2025

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Ether-Linked Glycerophospholipids Are Potential Chemo-Desensitisers and Are Associated With Overall Survival in Carcinoma Patients.
Yu-Ting Su, Wei-Chun Chang, Lumin Chen, Ying-Chun Yu, Wen-Jen Lin, Jheng-You Lin

J Cell Mol Med· December 2024

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Zein-PEG nanoparticles modified with hyaluronic acid for paclitaxel delivery in SKOV3 ovarian cancer cells.
Min-Hua Lai, Wen Jen Lin

Int J Biol Macromol· November 2024

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LipidSig 2.0: integrating lipid characteristic insights into advanced lipidomics data analysis.
Chia-Hsin Liu, Pei-Chun Shen, Wen-Jen Lin, Hsiu-Cheng Liu, Meng-Hsin Tsai

Nucleic Acids Res· July 2024

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iLipidome: enhancing statistical power and interpretability using hidden biosynthetic interdependencies in the lipidome.
Wen-Jen Lin, Austin W T Chiang, Evanston H Zhou, Chenguang Liang, Chia-Hsin Liu

bioRxiv· May 2024

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LipidSIM: Inferring mechanistic lipid biosynthesis perturbations from lipidomics with a flexible, low-parameter, Markov modeling framework.
Chenguang Liang, Sue Murray, Yang Li, Richard Lee, Audrey Low, Wen-Jen Lin

Metab Eng· March 2024

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DriverDBv4: a multi-omics integration database for cancer driver gene research.
Chia-Hsin Liu, Yo-Liang Lai, Pei-Chun Shen, Hsiu-Cheng Liu, Meng-Hsin Tsai, Wen-Jen Lin

Nucleic Acids Res· January 2024

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Phenotypic and metabolomic characteristics of mouse models of metabolic associated steatohepatitis.
Cian-Ru Yang, Wen-Jen Lin, Pei-Chun Shen, Pei-Yin Liao, Yuan-Chang Dai

Biomark Res· January 2024

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Synergistic cytotoxicity of irinotecan combined with polysaccharide-based nanoparticles for colorectal carcinoma.
Fang-Ting Pai, Wen Jen Lin

Biomater Adv· October 2023

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Improve BBB Penetration and Cytotoxicity of Palbociclib in U87-MG Glioblastoma Cells Delivered by Dual Peptide Functionalized Nanoparticles.
Yu-Chen Lo, Wen-Jen Lin

Pharmaceutics· October 2023

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Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism.
Merve Demir, L Peyton Russelburg, Wen-Jen Lin, Carlos H Trasviña-Arenas, Beili Huang

Nucleic Acids Res· February 2023

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The Dawn of a New Era in Drug Discovery? Drug Screening and the Increasing Biological Complexity of Testing Models.
Wen-Jen Lin

Chem Res Toxicol· January 2022

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Structure, function and evolution of the Helix-hairpin-Helix DNA glycosylase superfamily: Piecing together the evolutionary puzzle of DNA base damage repair mechanisms.
C H Trasviña-Arenas, Merve Demir, Wen-Jen Lin, Sheila S David

DNA Repair (Amst)· December 2021

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Ergosta-7,9(11),22-trien-3β-ol Attenuates Inflammatory Responses via Inhibiting MAPK/AP-1 Induced IL-6/JAK/STAT Pathways and Activating Nrf2/HO-1 Signaling in LPS-Stimulated Macrophage-like Cells.
Yi-Ping Huang, Dar-Ren Chen, Wen-Jen Lin, Yu-Hsien Lin, Jiann-Yeu Chen

Antioxidants (Basel)· September 2021

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Benefit of a Short Chain Peptide as a Targeting Ligand of Nanocarriers for a Brain-Driven Purpose.
Yu-Chen Lo, Wen-Jen Lin

Pharmaceutics· August 2021

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LipidSig: a web-based tool for lipidomic data analysis.
Wen-Jen Lin, Pei-Chun Shen, Hsiu-Cheng Liu, Yi-Chun Cho, Min-Kung Hsu, I-Chen Lin

Nucleic Acids Res· July 2021

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Structural Insights into the Mechanism of Base Excision by MBD4.
Lakshmi S Pidugu, Hilary Bright, Wen-Jen Lin, Chandrima Majumdar, Robert P Van Ostrand

J Mol Biol· July 2021

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Using bioinformatics approaches to investigate driver genes and identify BCL7A as a prognostic gene in colorectal cancer.
Jeffrey Yung-Chuan Chao, Hsin-Chuan Chang, Jeng-Kai Jiang, Chih-Yung Yang, Fang-Hsin Chen, Wen-Jen Lin, Yu-Feng Lin

Comput Struct Biotechnol J· July 2021

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Ergosta-7, 9 (11), 22-trien-3β-ol Interferes with LPS Docking to LBP, CD14, and TLR4/MD-2 Co-Receptors to Attenuate the NF-κB Inflammatory Pathway and .
Wen-Tsong Hsieh, Min-Hsien Hsu, Wen-Jen Lin, Yi-Cheng Xiao, Ping-Chiang Lyu, Wei-Yong Lin

Int J Mol Sci· June 2021

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