Publications by authors named "Wenchen Cai"

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Targeting the Secretin Receptor in Macrophages Attenuates Silica-Induced Pulmonary Fibrosis.
Yaqian Li, Tian Li, Fuyu Jin, Shupeng Liu, Dingjie Xu, Wenchen Cai

Cell Prolif· December 2025

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Effect of macrophage-to-myofibroblast transition on silicosis.
Fei Geng, Jingrou Xu, Xichen Ren, Ying Zhao, Yuhao Cai, Wenchen Cai

Animal Model Exp Med· February 2025

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IL-17A-neutralizing antibody ameliorates inflammation and fibrosis in rosacea by antagonizing the CXCL5/CXCR2 axis.
Chuanxi Zhang, Hui Jin, Yumeng Kang, Yiling Wu, Ruiping Zheng, Wenchen Cai

FASEB J· October 2024

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Paeoniflorin mitigates MMP-12 inflammation in silicosis via Yang-Yin-Qing-Fei Decoction in murine models.
Tian Li, Na Mao, Zihao Xie, Jianing Wang, Fuyu Jin, Wenchen Cai

Phytomedicine· July 2024

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Exercise training inhibits macrophage-derived IL-17A-CXCL5-CXCR2 inflammatory axis to attenuate pulmonary fibrosis in mice exposed to silica.
Fuyu Jin, Yaqian Li, Xuemin Gao, Xinyu Yang, Tian Li, Wenchen Cai

Sci Total Environ· December 2023

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ISRIB inhibits the senescence of type II pulmonary epithelial cells to alleviate pulmonary fibrosis induced by silica in mice.
Ya-Qian Li, Xu-Liang An, Fu-Yu Jin, Yi-Fei Bai, Tian Li, Wen-Chen Cai

Ecotoxicol Environ Saf· October 2023

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Quercetin Alleviates Pulmonary Fibrosis in Silicotic Mice by Inhibiting Macrophage Transition and TGF-β-Smad2/3 Pathway.
Fei Geng, Lan Zhao, Yuhao Cai, Ying Zhao, Fuyu Jin, Wenchen Cai

Curr Issues Mol Biol· April 2023

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Long-Term Administration of LL-37 Can Induce Irreversible Rosacea-like Lesion.
Chuanxi Zhang, Yumeng Kang, Ziyan Zhang, Heliang Liu, Hong Xu, Wenchen Cai

Curr Issues Mol Biol· March 2023

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Establishing a Silicosis Rat Model via Exposure of Whole-Body to Respirable Silica.
Fuyu Jin, Yaqian Li, Tian Li, Xinyu Yang, Wenchen Cai

J Vis Exp· October 2022

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Quercetin Alleviates Pulmonary Fibrosis in Mice Exposed to Silica by Inhibiting Macrophage Senescence.
Fei Geng, Mengying Xu, Lan Zhao, Haoming Zhang, Jiarui Li, Wenchen Cai

Front Pharmacol· July 2022

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Thalidomide Alleviates Pulmonary Fibrosis Induced by Silica in Mice by Inhibiting ER Stress and the TLR4-NF-κB Pathway.
Yaqian Li, Wenchen Cai, Fuyu Jin, Xiaojing Wang, Wenjing Liu

Int J Mol Sci· May 2022

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Minute Cellular Nodules as Early Lesions in Rats with Silica Exposure via Inhalation.
Yaqian Li, Fuyu Jin, Tian Li, Xinyu Yang, Wenchen Cai

Vet Sci· May 2022

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Oxamate Attenuates Glycolysis and ER Stress in Silicotic Mice.
Na Mao, Yuhang Fan, Wenjing Liu, Honghao Yang, Yi Yang, Wenchen Cai

Int J Mol Sci· March 2022

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OC-STAMP Overexpression Drives Lung Alveolar Epithelial Cell Type II Senescence in Silicosis.
Tian Li, Xin-Yu Yang, Ding-Jie Xu, Zi-Yi Gao, Yi-Bing Gao, Wen-Chen Cai

Oxid Med Cell Longev· January 2022

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MicroRNA-411-3p inhibits bleomycin-induced skin fibrosis by regulating transforming growth factor-β/Smad ubiquitin regulatory factor-2 signalling.
Ziyan Zhang, Xuemin Gao, Yang He, Yumeng Kang, Fuyu Jin, Wenchen Cai

J Cell Mol Med· December 2021

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Transcriptomic analysis identifies upregulation of secreted phosphoprotein 1 in silicotic rats.
Wenchen Cai, Bonan Zhang, Tian Li, Fuyu Jin, Yaqian Li

Exp Ther Med· June 2021

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Silica Perturbs Primary Cilia and Causes Myofibroblast Differentiation during Silicosis by Reduction of the KIF3A-Repressor GLI3 Complex.
Shifeng Li, Zhongqiu Wei, Gengxu Li, Qiaodan Zhang, Siyu Niu, Wenchen Cai

Theranostics· April 2021

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Ac-SDKP Attenuates Activation of Lung Macrophages and Bone Osteoclasts in Rats Exposed to Silica by Inhibition of TLR4 and RANKL Signaling Pathways.
Fuyu Jin, Fei Geng, Dingjie Xu, Yaqian Li, Tian Li, Wenchen Cai

J Inflamm Res· April 2021

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Matrix stiffness regulates α-TAT1-mediated acetylation of α-tubulin and promotes silica-induced epithelial-mesenchymal transition via DNA damage.
Gengxu Li, Si Chen, Yi Zhang, Hong Xu, Dingjie Xu, Wenchen Cai

J Cell Sci· January 2021

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Pulmonary Silicosis Alters MicroRNA Expression in Rat Lung and miR-411-3p Exerts Anti-fibrotic Effects by Inhibiting MRTF-A/SRF Signaling.
Xuemin Gao, Dingjie Xu, Shumin Li, Zhongqiu Wei, Shifeng Li, Wenchen Cai

Mol Ther Nucleic Acids· June 2020

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Differential expression of lncRNAs during silicosis and the role of LOC103691771 in myofibroblast differentiation induced by TGF-β1.
Wenchen Cai, Hong Xu, Bonan Zhang, Xuemin Gao, Shumin Li

Biomed Pharmacother· May 2020

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Inhibition of miR-155-5p Exerts Anti-Fibrotic Effects in Silicotic Mice by Regulating Meprin α.
Yingying Chen, Dingjie Xu, Jingxin Yao, Zhongqiu Wei, Shifeng Li, Wenchen Cai

Mol Ther Nucleic Acids· March 2020

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MiR-411-3p alleviates Silica-induced pulmonary fibrosis by regulating Smurf2/TGF-β signaling.
Xuemin Gao, Hong Xu, Dingjie Xu, Shumin Li, Zhongqiu Wei, Wenchen Cai

Exp Cell Res· March 2020

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Interaction of N-acetyl-seryl-aspartyl-lysyl-proline with the angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas axis attenuates pulmonary fibrosis in silicotic rats.
Xuemin Gao, Hong Xu, Bonan Zhang, Tao Tao, Yalou Liu, Wenchen Cai

Exp Physiol· October 2019

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Rho GDP dissociation inhibitor α silencing attenuates silicosis by inhibiting RhoA/Rho kinase signalling.
Zhongqiu Wei, Hong Xu, Yi Zhang, Xue Yi, Xinyu Yang, Wenchen Cai

Exp Cell Res· July 2019

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