Publications by authors named "Wesley D Penn"

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Deep Receptor Scanning Reveals General Sequence Constraints on GPCR Biosynthesis.
Austin Tedman, Muskan Goel, Sohan Shah, Mathew K Howard, Laura M Chamness, Wesley D Penn

bioRxiv· September 2025

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Ribosomal frameshifting selectively modulates the assembly, function, and pharmacological rescue of a misfolded CFTR variant.
Patrick J Carmody, Francis J Roushar, Austin Tedman, Wei Wang, Madeline Herwig, Wesley D Penn

Proc Natl Acad Sci U S A· October 2024

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Divergent folding-mediated epistasis among unstable membrane protein variants.
Laura M Chamness, Charles P Kuntz, Andrew G McKee, Wesley D Penn, Christopher M Hemmerich

Elife· July 2024

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Ribosomal Frameshifting Selectively Modulates the Assembly, Function, and Pharmacological Rescue of a Misfolded CFTR Variant.
Patrick Carmody, Francis J Roushar, Austin Tedman, Wei Wang, Madeline Herwig, Wesley D Penn

bioRxiv· July 2024

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Divergent Folding-Mediated Epistasis Among Unstable Membrane Protein Variants.
Laura M Chamness, Charles P Kuntz, Andrew G McKee, Wesley D Penn, Christopher M Hemmerich

bioRxiv· February 2024

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General trends in the effects of VX-661 and VX-445 on the plasma membrane expression of clinical CFTR variants.
Andrew G McKee, Eli F McDonald, Wesley D Penn, Charles P Kuntz, Karen Noguera

Cell Chem Biol· June 2023

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Chromenone derivatives as novel pharmacological chaperones for retinitis pigmentosa-linked rod opsin mutants.
Joseph T Ortega, Andrew G McKee, Francis J Roushar, Wesley D Penn, Jonathan P Schlebach

Hum Mol Genet· October 2022

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Abracadabra, One Becomes Two: The Importance of Context in Viral -1 Programmed Ribosomal Frameshifting.
Wesley D Penn, Suchetana Mukhopadhyay

mBio· August 2022

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Molecular basis for variations in the sensitivity of pathogenic rhodopsin variants to 9-cis-retinal.
Francis J Roushar, Andrew G McKee, Charles P Kuntz, Joseph T Ortega, Wesley D Penn

J Biol Chem· August 2022

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Coordination of -1 programmed ribosomal frameshifting by transcript and nascent chain features revealed by deep mutational scanning.
Patrick J Carmody, Matthew H Zimmer, Charles P Kuntz, Haley R Harrington, Kate E Duckworth, Wesley D Penn

Nucleic Acids Res· December 2021

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Molecular basis for the evolved instability of a human G-protein coupled receptor.
Laura M Chamness, Nathan B Zelt, Haley R Harrington, Charles P Kuntz, Brian J Bender, Wesley D Penn

Cell Rep· November 2021

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Regulators of Viral Frameshifting: More Than RNA Influences Translation Events.
Wesley D Penn, Haley R Harrington, Jonathan P Schlebach, Suchetana Mukhopadhyay

Annu Rev Virol· September 2020

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Cotranslational folding stimulates programmed ribosomal frameshifting in the alphavirus structural polyprotein.
Haley R Harrington, Matthew H Zimmer, Laura M Chamness, Veronica Nash, Wesley D Penn

J Biol Chem· May 2020

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Classification of the Molecular Defects Associated with Pathogenic Variants of the Creatine Transporter.
Martin D Salazar, Nathan B Zelt, Robert Saldivar, Charles P Kuntz, Sheng Chen, Wesley D Penn

Biochemistry· April 2020

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Probing biophysical sequence constraints within the transmembrane domains of rhodopsin by deep mutational scanning.
Wesley D Penn, Andrew G McKee, Charles P Kuntz, Hope Woods, Veronica Nash

Sci Adv· March 2020

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Folding and Misfolding of Human Membrane Proteins in Health and Disease: From Single Molecules to Cellular Proteostasis.
Justin T Marinko, Hui Huang, Wesley D Penn, John A Capra, Jonathan P Schlebach

Chem Rev· May 2019

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Contribution of Cotranslational Folding Defects to Membrane Protein Homeostasis.
Francis J Roushar, Timothy C Gruenhagen, Wesley D Penn, Bian Li, Jens Meiler

J Am Chem Soc· January 2019

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The Plasmodium falciparum exported protein PF3D7_0402000 binds to erythrocyte ankyrin and band 4.1.
Bikash Shakya, Wesley D Penn, Ernesto S Nakayasu, Douglas J LaCount

Mol Biochem Parasitol· September 2017

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