Publications by authors named "Whitney Helms"

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Assessing the impact and risk of immunomodulatory compounds on pregnancy.
Joanne Kwak-Kim, Curtis C Maier, Caren M Villano, Christopher J Bowman, Frank R Brennan, Whitney Helms

J Reprod Immunol· June 2025

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FDA Approval Summary: Pembrolizumab, Atezolizumab, and Cemiplimab-rwlc as Single Agents for First-Line Treatment of Advanced/Metastatic PD-L1-High NSCLC.
Oladimeji Akinboro, Erin Larkins, Lee H Pai-Scherf, Luckson N Mathieu, Yi Ren, Whitney S Helms

Clin Cancer Res· June 2022

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FDA Approval Summary: Capmatinib and Tepotinib for the Treatment of Metastatic NSCLC Harboring MET Exon 14 Skipping Mutations or Alterations.
Luckson N Mathieu, Erin Larkins, Oladimeji Akinboro, Pourab Roy, Anup K Amatya, Whitney S Helms

Clin Cancer Res· January 2022

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FDA Approval Summary: Pralsetinib for the Treatment of Lung and Thyroid Cancers With Gene Mutations or Fusions.
Janice Kim, Diana Bradford, Erin Larkins, Lee H Pai-Scherf, Somak Chatterjee, Whitney S Helms

Clin Cancer Res· October 2021

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FDA Approval Summary: Selumetinib for Plexiform Neurofibroma.
Denise Casey, Suzanne Demko, Arup Sinha, Pallavi S Mishra-Kalyani, Yuan-Li Shen, Whitney S Helms

Clin Cancer Res· August 2021

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FDA Approval Summary: Lurbinectedin for the Treatment of Metastatic Small Cell Lung Cancer.
Sonia Singh, Adnan A Jaigirdar, Flora Mulkey, Joyce Cheng, Salaheldin S Hamed, Whitney S Helms

Clin Cancer Res· May 2021

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FDA Approval Summary: Selpercatinib for the Treatment of Lung and Thyroid Cancers with Gene Mutations or Fusions.
Diana Bradford, Erin Larkins, Sirisha L Mushti, Lisa Rodriguez, Amy M Skinner, Whitney S Helms

Clin Cancer Res· April 2021

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FDA Approval Summary: Entrectinib for the Treatment of gene Fusion Solid Tumors.
Leigh Marcus, Martha Donoghue, Stephanie Aungst, Claire E Myers, Whitney S Helms

Clin Cancer Res· February 2021

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Pivotal Considerations for Optimal Deployment of Healthy Volunteers in Oncology Drug Development.
Mariam A Ahmed, Chirag Patel, Nicole Drezner, Whitney Helms, Weiwei Tan

Clin Transl Sci· January 2020

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FDA Approval Summary: Trabectedin for Unresectable or Metastatic Liposarcoma or Leiomyosarcoma Following an Anthracycline-Containing Regimen.
Amy Barone, Dow-Chung Chi, Marc R Theoret, Huanyu Chen, Kun He, Whitney S Helms

Clin Cancer Res· December 2017

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FDA Approval Summary: Accelerated Approval of Pembrolizumab for Second-Line Treatment of Metastatic Melanoma.
Meredith K Chuk, Jennie T Chang, Marc R Theoret, Emmanuel Sampene, Kun He, Whitney S Helms

Clin Cancer Res· October 2017

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U.S. FDA Approval Summary: Nivolumab for Treatment of Unresectable or Metastatic Melanoma Following Progression on Ipilimumab.
Maitreyee Hazarika, Meredith K Chuk, Marc R Theoret, Sirisha Mushti, Kun He, Whitney S Helms

Clin Cancer Res· July 2017

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FDA Approval Summary: TAS-102.
Leigh Marcus, Steven J Lemery, Sachia Khasar, Emily Wearne, Whitney S Helms

Clin Cancer Res· June 2017

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FDA Approval Summary: Sonidegib for Locally Advanced Basal Cell Carcinoma.
Denise Casey, Suzanne Demko, Stacy Shord, Hong Zhao, Huanyu Chen, Whitney Helms

Clin Cancer Res· May 2017

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FDA Approval: Alectinib for the Treatment of Metastatic, ALK-Positive Non-Small Cell Lung Cancer Following Crizotinib.
Erin Larkins, Gideon M Blumenthal, Huanyu Chen, Kun He, Rajiv Agarwal, Whitney Helms

Clin Cancer Res· November 2016

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Cytokine release: A workshop proceedings on the state-of-the-science, current challenges and future directions.
Christine Grimaldi, Deborah Finco, Madeline M Fort, Daniel Gliddon, Kirsty Harper, Whitney S Helms

Cytokine· September 2016

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FDA Approval Summary: Lenvatinib for Progressive, Radio-iodine-Refractory Differentiated Thyroid Cancer.
Abhilasha Nair, Steven J Lemery, Jun Yang, Anshu Marathe, Liang Zhao, Whitney Helms

Clin Cancer Res· December 2015

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FDA Approval Summary: Ramucirumab for Gastric Cancer.
Sandra J Casak, Ibilola Fashoyin-Aje, Steven J Lemery, Lillian Zhang, Runyan Jin, Whitney Helms

Clin Cancer Res· August 2015

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FDA approval: ceritinib for the treatment of metastatic anaplastic lymphoma kinase-positive non-small cell lung cancer.
Sean Khozin, Gideon M Blumenthal, Lijun Zhang, Shenghui Tang, Margaret Brower, Whitney Helms

Clin Cancer Res· June 2015

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FDA approval summary: vemurafenib for treatment of unresectable or metastatic melanoma with the BRAFV600E mutation.
Geoffrey Kim, Amy E McKee, Yang-Min Ning, Maitreyee Hazarika, Marc Theoret, Whitney S Helms

Clin Cancer Res· October 2014

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Regulation of immunotherapeutic products for cancer and FDA's role in product development and clinical evaluation.
Ramjay S Vatsan, Peter F Bross, Ke Liu, Marc Theoret, Angelo R De Claro, Whitney Helms

J Immunother Cancer· June 2014

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U.S. Food and Drug Administration approval: crizotinib for treatment of advanced or metastatic non-small cell lung cancer that is anaplastic lymphoma kinase positive.
Shakun M Malik, Virginia Ellen Maher, Karen E Bijwaard, Robert L Becker, Lijun Zhang, Whitney Helms

Clin Cancer Res· April 2014

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Contrasting roles for all-trans retinoic acid in TGF-beta-mediated induction of Foxp3 and Il10 genes in developing regulatory T cells.
Craig L Maynard, Robin D Hatton, Whitney S Helms, James R Oliver, Charles B Stephensen

J Exp Med· February 2009

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Modulation of NFAT-dependent gene expression by the RhoA signaling pathway in T cells.
Whitney S Helms, Jerry L Jeffrey, Derek A Holmes, Michael B Townsend, Neil A Clipstone

J Leukoc Biol· August 2007

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Transforming growth factor-beta induces development of the T(H)17 lineage.
Paul R Mangan, Laurie E Harrington, Darrell B O'Quinn, Whitney S Helms, Daniel C Bullard

Nature· May 2006

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