Publications by authors named "William D Martin"

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T cell epitope content comparison using EpiCC correlates with vaccine efficacy against heterologous porcine reproductive and respiratory syndrome virus type 2 strains.
J Mark Hammer, Andres H Gutierrez, Lucas Huntimer, Benjamin Gabriel, William D Martin

Front Microbiol· June 2025

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Regulatory T cell epitope content in human antibodies decreases during maturation.
Andres H Gutierrez, Frances E Terry, Amy S Rosenberg, William D Martin, Anne S De Groot

Front Immunol· May 2025

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Assessing the immunogenicity risk of salmon calcitonin peptide impurities using and methods.
Brian J Roberts, Aimee E Mattei, Kristina E Howard, James L Weaver, Hao Liu, William D Martin

Front Pharmacol· August 2024

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In silico methods for immunogenicity risk assessment and human homology screening for therapeutic antibodies.
Aimee E Mattei, Andres H Gutierrez, Soorya Seshadri, Jacob Tivin, Matt Ardito, William D Martin

MAbs· March 2024

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Optimization of therapeutic antibodies for reduced self-association and non-specific binding via interpretable machine learning.
Emily K Makowski, Tiexin Wang, Jennifer M Zupancic, Jie Huang, Lina Wu, William D Martin

Nat Biomed Eng· January 2024

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Neoadjuvant personalized cancer vaccines: the final frontier?
Guilhem Richard, Nicole Ruggiero, Gary D Steinberg, William D Martin, Anne S De Groot

Expert Rev Vaccines· January 2024

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Does human homology reduce the potential immunogenicity of non-antibody scaffolds?
Anne S De Groot, Sundos Khan, Aimee E Mattei, Sandra Lelias, William D Martin

Front Immunol· December 2023

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Immunogenicity risk assessment of synthetic peptide drugs and their impurities.
Anne S De Groot, Brian J Roberts, Aimee Mattei, Sandra Lelias, Christine Boyle, William D Martin

Drug Discov Today· October 2023

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Identification of immunodominant T cell epitopes induced by natural Zika virus infection.
Christopher S Eickhoff, Krystal A Meza, Frances E Terry, Chase G Colbert, Azra Blazevic, William D Martin

Front Immunol· September 2023

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Immunogenicity Assessment for Sequences Containing Unnatural Amino Acids: A Method Using Existing Algorithm Infrastructure and a Vision for Future Enhancements.
Aimee E Mattei, Andres H Gutierrez, William D Martin, Frances E Terry, Brian J Roberts

Front Drug Discov (Lausanne)· October 2022

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Neoantigen-based personalized cancer vaccines: the emergence of precision cancer immunotherapy.
Guilhem Richard, Michael F Princiotta, Dominique Bridon, William D Martin, Gary D Steinberg

Expert Rev Vaccines· February 2022

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Identification, Selection and Immune Assessment of Liver Stage CD8 T Cell Epitopes From .
Kenneth D Tucker, Brian C Schanen, Timothy W Phares, Emily Sassano, Frances E Terry, William D Martin

Front Immunol· October 2021

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Bridging Computational Vaccinology and Vaccine Development Through Systematic Identification, Characterization, and Downselection of Conserved and Variable Circumsporozoite Protein CD4 T Cell Epitopes From Diverse Strains.
Amy R Noe, Frances E Terry, Brian C Schanen, Emily Sassano, Pooja Hindocha, William D Martin

Front Immunol· October 2021

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Immune Tolerance-Adjusted Personalized Immunogenicity Prediction for Pompe Disease.
Anne S De Groot, Ankit K Desai, Sandra Lelias, S M Shahjahan Miah, Frances E Terry, William D Martin

Front Immunol· October 2021

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Identification and Immune Assessment of T Cell Epitopes in Five Blood Stage Antigens to Facilitate Vaccine Candidate Selection and Optimization.
Vinayaka Kotraiah, Timothy W Phares, Frances E Terry, Pooja Hindocha, Sarah E Silk, William D Martin

Front Immunol· October 2021

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Development of a novel fully functional coagulation factor VIII with reduced immunogenicity utilizing an in silico prediction and deimmunization approach.
Karina Winterling, William D Martin, Anne S De Groot, Jens Daufenbach, Steffen Kistner

J Thromb Haemost· September 2021

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identification and modification of T cell epitopes in pertussis antigens associated with tolerance.
Corine Kruiswijk, Guilhem Richard, Merijn L M Salverda, Pooja Hindocha, William D Martin

Hum Vaccin Immunother· June 2021

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New Immunoinformatics Tools for Swine: Designing Epitope-Driven Vaccines, Predicting Vaccine Efficacy, and Making Vaccines on Demand.
Lenny Moise, Andres H Gutiérrez, Sundos Khan, Swan Tan, Matt Ardito, William D Martin

Front Immunol· May 2021

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Multi-step screening of neoantigens' HLA- and TCR-interfaces improves prediction of survival.
Guilhem Richard, Anne S De Groot, Gary D Steinberg, Tzintzuni I Garcia, Alec Kacew, William D Martin

Sci Rep· May 2021

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Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools.
Anne S De Groot, Leonard Moise, Frances Terry, Andres H Gutierrez, Pooja Hindocha, William D Martin

Front Immunol· March 2021

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Identification of a potent regulatory T cell epitope in factor V that modulates CD4+ and CD8+ memory T cell responses.
Anne S De Groot, Amy S Rosenberg, S M Shahjahan Miah, Gail Skowron, Brian J Roberts, William D Martin

Clin Immunol· March 2021

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Exploit T cell Immunity for Rapid, Safe and Effective COVID-19 Vaccines.
Leonard Moise, Ted M Ross, Daniel F Hoft, William D Martin, Anne S De Groot

Expert Rev Vaccines· September 2020

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T cell epitope content comparison (EpiCC) analysis demonstrates a bivalent PCV2 vaccine has greater T cell epitope overlap with field strains than monovalent PCV2 vaccines.
Meggan Bandrick, Andres H Gutiérrez, Prerak Desai, Gonzalo Rincon, William D Martin

Vet Immunol Immunopathol· May 2020

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Differential functional patterns of memory CD4 and CD8 T-cells from volunteers immunized with Ty21a typhoid vaccine observed using a recombinant Escherichia coli system expressing S. Typhi proteins.
Rosângela Salerno-Gonçalves, Hervé Tettelin, David Luo, Qin Guo, Matthew T Ardito, William D Martin

Vaccine· January 2020

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Therapeutic administration of Tregitope-Human Albumin Fusion with Insulin Peptides to promote Antigen-Specific Adaptive Tolerance Induction.
Anne S De Groot, Gail Skowron, James Robert White, Christine Boyle, Guilhem Richard, William D Martin

Sci Rep· November 2019

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