Publications by authors named "William F Pool"

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Pharmacokinetics, metabolism, and excretion of [14C]axitinib, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in humans.
Bill J Smith, Yazdi Pithavala, Hai-Zhi Bu, Ping Kang, Brian Hee, William F Pool

Drug Metab Dispos· May 2014

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Pharmacokinetics, distribution, and metabolism of [14C]sunitinib in rats, monkeys, and humans.
Bill Speed, Hai-Zhi Bu, William F Pool, Geoffrey W Peng, Ellen Y Wu

Drug Metab Dispos· March 2012

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Identification of primary and sequential bioactivation pathways of carbamazepine in human liver microsomes using liquid chromatography/tandem mass spectrometry.
Hai-Zhi Bu, Ping Zhao, Deepak K Dalvie, William F Pool

Rapid Commun Mass Spectrom· November 2007

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Evaluation of capravirine as a CYP3A probe substrate: in vitro and in vivo metabolism of capravirine in rats and dogs.
Hai-Zhi Bu, Ping Zhao, Ping Kang, William F Pool, Ellen Y Wu

Drug Metab Dispos· September 2007

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A unique example of drug metabolism: tetra- and penta-oxygenation reactions of capravirine in rats, dogs and humans.
Hai-Zhi Bu, William F Pool, Ellen Y Wu, Bhasker V Shetty

Drug Metab Lett· January 2007

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Identification of enzymes responsible for primary and sequential oxygenation reactions of capravirine in human liver microsomes.
Hai-Zhi Bu, Ping Zhao, Ping Kang, William F Pool, Ellen Y Wu

Drug Metab Dispos· November 2006

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Human in vitro glutathionyl and protein adducts of carbamazepine-10,11-epoxide, a stable and pharmacologically active metabolite of carbamazepine.
Hai-Zhi Bu, Ping Kang, Alan J Deese, Ping Zhao, William F Pool

Drug Metab Dispos· December 2005

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A simple sequential incubation method for deconvoluting the complicated sequential metabolism of capravirine in humans.
Hai-Zhi Bu, Ping Kang, Ping Zhao, William F Pool, Ellen Y Wu

Drug Metab Dispos· October 2005

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Metabolism and excretion of capravirine, a new non-nucleoside reverse transcriptase inhibitor, alone and in combination with ritonavir in healthy volunteers.
Hai-Zhi Bu, William F Pool, Ellen Y Wu, Susan R Raber, Michael A Amantea

Drug Metab Dispos· July 2004

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Metabolic activation of troglitazone: identification of a reactive metabolite and mechanisms involved.
Kan He, Rasmy E Talaat, William F Pool, Michael D Reily, Jessica E Reed

Drug Metab Dispos· June 2004

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Determination of tacrine metabolites in microsomal incubate by high performance liquid chromatography-nuclear magnetic resonance/mass spectrometry with a column trapping system.
Donghui Bao, Venkataraman Thanabal, William F Pool

J Pharm Biomed Anal· April 2002

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