Publications by authors named "William F Weiss"

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Quantitation of soluble aggregates by sedimentation velocity analytical ultracentrifugation using an optical alignment system - Aspects of method validation.
Brandon L Doyle, Adam P Rauk, William F Weiss, Ivan L Budyak

Anal Biochem· September 2020

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Understanding the Increased Aggregation Propensity of a Light-Exposed IgG1 Monoclonal Antibody Using Hydrogen Exchange Mass Spectrometry, Biophysical Characterization, and Structural Analysis.
Rupesh Bommana, Qing Chai, Christian Schöneich, William F Weiss, Ranajoy Majumdar

J Pharm Sci· June 2018

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An optical alignment system improves precision of soluble aggregate quantitation by sedimentation velocity analytical ultracentrifugation.
Brandon L Doyle, Ivan L Budyak, Adam P Rauk, William F Weiss

Anal Biochem· August 2017

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Technical Decision Making With Higher Order Structure Data: Perspectives on Higher Order Structure Characterization From the Biopharmaceutical Industry.
William F Weiss, John P Gabrielson, Wasfi Al-Azzam, Guodong Chen, Darryl L Davis

J Pharm Sci· December 2016

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Estimating analytical variability in two-dimensional data.
Ivan L Budyak, Kristi L Griffiths, William F Weiss

Anal Biochem· November 2016

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Variability in Flow-Imaging Microscopy Measurements and Considerations for Biopharmaceutical Development.
Adam P Rauk, Kristi L Griffiths, Melody D Gossage, William F Weiss

J Pharm Sci· November 2016

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Technical decision-making with higher order structure data: specific binding of a nonionic detergent perturbs higher order structure of a therapeutic monoclonal antibody.
Ivan L Budyak, Brandon L Doyle, William F Weiss

J Pharm Sci· April 2015

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Technical decision-making with higher order structure data: starting a new dialogue.
John P Gabrielson, William F Weiss

J Pharm Sci· April 2015

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Arrhenius time-scaled least squares: a simple, robust approach to accelerated stability data analysis for bioproducts.
Adam P Rauk, Kevin Guo, Yanling Hu, Suntara Cahya, William F Weiss

J Pharm Sci· August 2014

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Reduction of the C191-C220 disulfide of α-chymotrypsinogen A reduces nucleation barriers for aggregation.
William F Weiss, Aming Zhang, Magdalena I Ivanova, Erinc Sahin, Jacob L Jordan

Biophys Chem· January 2014

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Aggregation and pH-temperature phase behavior for aggregates of an IgG2 antibody.
Erinc Sahin, William F Weiss, Andrew M Kroetsch, Kevin R King, R Kendall Kessler

J Pharm Sci· May 2012

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High-throughput analysis of concentration-dependent antibody self-association.
Shantanu V Sule, Muppalla Sukumar, William F Weiss, Anna Marie Marcelino-Cruz, Tyler Sample

Biophys J· October 2011

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Computational design and biophysical characterization of aggregation-resistant point mutations for γD crystallin illustrate a balance of conformational stability and intrinsic aggregation propensity.
Erinc Sahin, Jacob L Jordan, Michelle L Spatara, Andrea Naranjo, Joseph A Costanzo, William F Weiss

Biochemistry· February 2011

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Molecular level insights into thermally induced α-chymotrypsinogen A amyloid aggregation mechanism and semiflexible protofibril morphology.
Aming Zhang, Jacob L Jordan, Magdalena I Ivanova, William F Weiss, Christopher J Roberts

Biochemistry· December 2010

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Characterization of high-molecular-weight nonnative aggregates and aggregation kinetics by size exclusion chromatography with inline multi-angle laser light scattering.
Yi Li, William F Weiss, Christopher J Roberts

J Pharm Sci· November 2009

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Principles, approaches, and challenges for predicting protein aggregation rates and shelf life.
William F Weiss, Teresa M Young, Christopher J Roberts

J Pharm Sci· April 2009

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Nucleation, growth, and activation energies for seeded and unseeded aggregation of alpha-chymotrypsinogen A.
Jennifer M Andrews, William F Weiss, Christopher J Roberts

Biochemistry· February 2008

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Nonnative protein polymers: structure, morphology, and relation to nucleation and growth.
William F Weiss, Travis K Hodgdon, Eric W Kaler, Abraham M Lenhoff, Christopher J Roberts

Biophys J· December 2007

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