Publications by authors named "William Fanslow"

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Altering Antibody-Drug Conjugate Binding to the Neonatal Fc Receptor Impacts Efficacy and Tolerability.
Kevin J Hamblett, Tiep Le, Brooke M Rock, Dan A Rock, Sophia Siu, William C Fanslow

Mol Pharm· July 2016

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SLC46A3 Is Required to Transport Catabolites of Noncleavable Antibody Maytansine Conjugates from the Lysosome to the Cytoplasm.
Kevin J Hamblett, Allison P Jacob, Jesse L Gurgel, Mark E Tometsko, Brooke M Rock, William C Fanslow

Cancer Res· December 2015

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Intracellular Catabolism of an Antibody Drug Conjugate with a Noncleavable Linker.
Brooke M Rock, Mark E Tometsko, Sonal K Patel, Kevin J Hamblett, William C Fanslow

Drug Metab Dispos· September 2015

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AMG 595, an Anti-EGFRvIII Antibody-Drug Conjugate, Induces Potent Antitumor Activity against EGFRvIII-Expressing Glioblastoma.
Kevin J Hamblett, Carl J Kozlosky, Sophia Siu, Wesley S Chang, Hua Liu, William C Fanslow

Mol Cancer Ther· July 2015

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A novel antibody engineering strategy for making monovalent bispecific heterodimeric IgG antibodies by electrostatic steering mechanism.
Zhi Liu, Esther C Leng, Kannan Gunasekaran, Martin Pentony, Min Shen, William Fanslow

J Biol Chem· March 2015

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Asymmetrical Fc engineering greatly enhances antibody-dependent cellular cytotoxicity (ADCC) effector function and stability of the modified antibodies.
Zhi Liu, Kannan Gunasekaran, Wei Wang, Vladimir Razinkov, Laura Sekirov, William Fanslow

J Biol Chem· February 2014

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Tumor penetration and epidermal growth factor receptor saturation by panitumumab correlate with antitumor activity in a preclinical model of human cancer.
Daniel J Freeman, Kevin McDorman, Selam Ogbagabriel, Carl Kozlosky, Bing-Bing Yang, William Fanslow

Mol Cancer· July 2012

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AMG 386, a selective angiopoietin 1/2-neutralizing peptibody, inhibits angiogenesis in models of ocular neovascular diseases.
Jonathan D Oliner, James Bready, Linh Nguyen, Juan Estrada, Eunju Hurh, William Fanslow

Invest Ophthalmol Vis Sci· April 2012

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Herpesvirus saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor.
Zhengbin Yao, William C Fanslow, Michael F Seldin, Anne-Marie Rousseau, Sally L Painter

J Immunol· November 2011

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Partial immune reconstitution of X-linked hyper IgM syndrome with recombinant CD40 ligand.
Ashish Jain, Joseph A Kovacs, David L Nelson, Stephen A Migueles, Stefania Pittaluga, William Fanslow

Blood· October 2011

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Inhibition of angiopoietin-2 in LuCaP 23.1 prostate cancer tumors decreases tumor growth and viability.
Colm Morrissey, Alex Dowell, Theodore D Koreckij, Holly Nguyen, Bryce Lakely, William C Fanslow

Prostate· December 2010

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Nectin-like protein 2 defines a subset of T-cell zone dendritic cells and is a ligand for class-I-restricted T-cell-associated molecule.
Laurent Galibert, Geoffrey S Diemer, Zhi Liu, Richard S Johnson, Jeffrey L Smith, William C Fanslow

J Biol Chem· June 2005

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Inhibition of VEGF-dependent multistage carcinogenesis by soluble EphA receptors.
Nikki Cheng, Dana Brantley, Wei Bin Fang, Hua Liu, William Fanslow

Neoplasia· July 2004

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Angiopoietin/Tek interactions regulate mmp-9 expression and retinal neovascularization.
Arup Das, William Fanslow, Douglas Cerretti, Erin Warren, Nicholas Talarico

Lab Invest· November 2003

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Activation-induced cell death of aggressive histology lymphomas by CD40 stimulation: induction of bax.
Jamie L Szocinski, Annette R Khaled, Julie Hixon, Douglas Halverson, Satoshi Funakoshi, William C Fanslow

Blood· July 2002

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Ox40 costimulation enhances the development of T cell responses induced by dendritic cells in vivo.
Thibaut De Smedt, Jeffrey Smith, Peter Baum, William Fanslow, Eric Butz

J Immunol· January 2002

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