Publications by authors named "William Jacobs"

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The unique role of -mediated noncanonical mismatch repair in resistance evolution.
Isabel Martín-Blecua, Jorge Sastre-Domínguez, José Ramón Valverde, Pablo García-Bravo, Ángel Ruiz-Enamorado, William R Jacobs

mBio· December 2025

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Cooperation and Competition of Base Pairing and Electrostatic Interactions in Mixtures of DNA Nanostars and Polylysine.
Gabrielle R Abraham, Tianhao Li, Anna Nguyen, William M Jacobs, Omar A Saleh

J Am Chem Soc· November 2025

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Luciferase reporter mycobacteriophage (TM4::) enables rapid assessment of drug susceptibilities and inducible macrolide resistance in complex.
Saranathan Rajagopalan, Lahari Das, Donna J Kohlerschmidt, Amy K Rourke, Salika M Shakir, William R Jacobs

J Clin Microbiol· September 2025

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Loss of the ESX-5 secretion locus in reshapes the mycomembrane and enhances ESX-1 substrate secretion.
Benjamin Koleske, Saranathan Rajagopalan, Courtney Schill, Shichun Lun, Catherine Vilchèze, William R Jacobs

Proc Natl Acad Sci U S A· September 2025

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When is Not Enough: Evaluating Simple Metrics for Predicting Phase Separation of Intrinsically Disordered Proteins.
Wesley W Oliver, William M Jacobs, Michael A Webb

J Phys Chem B· September 2025

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Vitamin C potentiates the killing of by bedaquiline through metabolic disruption.
Catherine Vilchèze, Saranathan Rajagopalan, Raja Sab Kalluru, Niaz Banaei, William R Jacobs

mBio· August 2025

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Active DNA demethylation upstream of rod-photoreceptor fate determination is required for retinal development.
Ismael Hernández-Núñez, Alaina Urman, Xiaodong Zhang, William Jacobs, Christy Hoffmann

PLoS Biol· August 2025

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Predicting heteropolymer phase separation using two-chain contact maps.
Jessica Jin, Wesley Oliver, Michael A Webb, William M Jacobs

J Chem Phys· July 2025

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Loss of the locus drives adaptive transcriptional responses and hypervirulence of lineage 2.
Benjamin Koleske, Courtney Schill, Saranathan Rajagopalan, Somnath Shee, Yazmin B Martinez-Martinez, William R Jacobs

Sci Adv· July 2025

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Interfacial effects determine nonequilibrium phase behaviors in chemically driven fluids.
Yongick Cho, William M Jacobs

Proc Natl Acad Sci U S A· July 2025

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Cooperation and competition of basepairing and electrostatic interactions in mixtures of DNA nanostars and polylysine.
Gabrielle R Abraham, Tianhao Li, Anna Nguyen, William M Jacobs, Omar A Saleh

ArXiv· July 2025

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An unusual genetic switch controls pathogenesis, antibiotic resistance and colony morphology.
Hannah J Nilsson, Zoe Netter, Miles Tuncel, Nicholas E Garelis, Nabila Siddiqui, William R Jacobs

bioRxiv· July 2025

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Mycobacteriophage-mediated gene transfer enables in vitro drug screening and in vivo tracking of .
Lahari Das, Bing Chen, Saranathan Rajagopalan, Catherine Vilcheze, Claire V Mulholland, William R Jacobs

Proc Natl Acad Sci U S A· June 2025

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The unique role of -mediated non-canonical mismatch repair in resistance evolution.
Isabel Martín-Blecua, José Ramón Valverde, Pablo García-Bravo, Ángel Ruiz-Enamorado, Rafael Prados-Rosales, William R Jacobs

bioRxiv· June 2025

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Predicting Heteropolymer Phase Separation Using Two-Chain Contact Maps.
Jessica Jin, Wesley Oliver, Michael A Webb, William M Jacobs

ArXiv· May 2025

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Engineered Mycobacteriophage TM4::GeNL Rapidly Determines Bedaquiline, Pretomanid, Linezolid, Rifampicin, and Clofazimine Sensitivity in Mycobacterium tuberculosis Clinical Isolates.
Saranathan Rajagopalan, Amy K Rourke, Emmanuel Asare, Donna J Kohlerschmidt, Lahari Das, William R Jacobs

J Infect Dis· April 2025

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The underappreciated role of nonspecific interactions in the crystallization of DNA-coated colloids.
Hunter Seyforth, Sambarta Chatterjee, Thomas E Videbæk, Manodeep Mondal, William M Jacobs

Soft Matter· April 2025

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Active DNA demethylation is upstream of rod-photoreceptor fate determination and required for retinal development.
Ismael Hernández-Núñez, Alaina Urman, Xiaodong Zhang, William Jacobs, Christy Hoffman

bioRxiv· February 2025

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Emergence of Multiphase Condensates from a Limited Set of Chemical Building Blocks.
Fan Chen, William M Jacobs

J Chem Theory Comput· August 2024

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The SapM phosphatase can arrest phagosome maturation in an ESX-1 independent manner in and BCG.
Christian Xander, Saranathan Rajagopalan, William R Jacobs, Miriam Braunstein

Infect Immun· July 2024

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Boosting Immunogenicity of a Recombinant Strain via Zinc-Dependent Ribosomal Proteins.
Shivani Singh, David Kanzin, Sarah Chavez, Noemi Alejandra Saavedra-Avila, Tony W Ng, William R Jacobs

Biomedicines· July 2024

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A viral vaccine design harnessing prior BCG immunization confers protection against Ebola virus.
Tony W Ng, Wakako Furuyama, Ariel S Wirchnianski, Noemí A Saavedra-Ávila, Christopher T Johndrow, William R Jacobs

Front Immunol· July 2024

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Competition between Self-Assembly and Phase Separation Governs High-Temperature Condensation of a DNA Liquid.
Omkar Hegde, Tianhao Li, Anjali Sharma, Marco Borja, William M Jacobs

Phys Rev Lett· May 2024

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A viral vaccine design harnessing prior BCG immunization confers protection against Ebola virus.
Tony W Ng, Wakako Furuyama, Ariel S Wirchnianski, Noemí A Saavedra-Ávila, Christopher T Johndrow, William R Jacobs

bioRxiv· May 2024

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Intravenous Immunization with Triple Auxotrophs of : A novel vaccine strategy against tuberculosis.
Catherine Vilchèze, Saranathan Rajagopalan, William R Jacobs

bioRxiv· May 2024

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