Publications by authors named "William M Keyes"

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Cellular senescence and developmental defects.
Annabelle Klein, Muriel Rhinn, William M Keyes

FEBS J· March 2023

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Senescence diversity in muscle aging.
Matej Durik, William M Keyes

Nat Aging· July 2022

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Aberrant induction of p19Arf-mediated cellular senescence contributes to neurodevelopmental defects.
Muriel Rhinn, Irene Zapata-Bodalo, Annabelle Klein, Jean-Luc Plassat, Tania Knauer-Meyer, William M Keyes

PLoS Biol· June 2022

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Cell cycle gene regulation dynamics revealed by RNA velocity and deep-learning.
Andrea Riba, Attila Oravecz, Matej Durik, Sara Jiménez, Violaine Alunni, William M Keyes

Nat Commun· May 2022

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Endothelial cells give a boost to senescence surveillance.
Daniel Sampaio Gonçalves, William M Keyes

Genes Dev· May 2022

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The senotherapeutic drug ABT-737 disrupts aberrant p21 expression to restore liver regeneration in adult mice.
Birgit Ritschka, Tania Knauer-Meyer, Daniel Sampaio Gonçalves, Alba Mas, Jean-Luc Plassat, William M Keyes

Genes Dev· April 2020

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Cellular senescence in development, regeneration and disease.
Muriel Rhinn, Birgit Ritschka, William M Keyes

Development· October 2019

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Detection of Senescence Markers During Mammalian Embryonic Development.
Mekayla Storer, William M Keyes

Methods Mol Biol· January 2018

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The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration.
Birgit Ritschka, Mekayla Storer, Alba Mas, Florian Heinzmann, Mari Carmen Ortells, William M Keyes

Genes Dev· January 2017

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Developing senescence to remodel the embryo.
Mekayla Storer, William M Keyes

Commun Integr Biol· October 2014

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New insights into skin stem cell aging and cancer.
M Carmen Ortells, William M Keyes

Biochem Soc Trans· June 2014

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Rearranging senescence: transposable elements become active in aging cells (Comment on DOI 10.1002/bies.201300097).
William M Keyes

Bioessays· December 2013

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Senescence is a developmental mechanism that contributes to embryonic growth and patterning.
Mekayla Storer, Alba Mas, Alexandre Robert-Moreno, Matteo Pecoraro, M Carmen Ortells, William M Keyes

Cell· November 2013

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Chromatin-bound IκBα regulates a subset of polycomb target genes in differentiation and cancer.
María Carmen Mulero, Dolors Ferres-Marco, Abul Islam, Pol Margalef, Matteo Pecoraro, William M Keyes

Cancer Cell· August 2013

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DPY30 regulates pathways in cellular senescence through ID protein expression.
Elisabeth Simboeck, Arantxa Gutierrez, Luca Cozzuto, Malte Beringer, Livia Caizzi, William M Keyes

EMBO J· August 2013

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Epidermal stem cells undergo age-associated changes.
Jason Doles, William M Keyes

Aging (Albany NY)· January 2013

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Age-associated inflammation inhibits epidermal stem cell function.
Jason Doles, Mekayla Storer, Luca Cozzuto, Guglielmo Roma, William M Keyes

Genes Dev· October 2012

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ΔNp63α is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis.
William M Keyes, Matteo Pecoraro, Victoria Aranda, Emma Vernersson-Lindahl, Wangzhi Li

Cell Stem Cell· February 2011

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TAp63 induces senescence and suppresses tumorigenesis in vivo.
Xuecui Guo, William M Keyes, Cristian Papazoglu, Johannes Zuber, Wangzhi Li

Nat Cell Biol· December 2009

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Neural potential of a stem cell population in the hair follicle.
John L Mignone, Jose L Roig-Lopez, Natalia Fedtsova, Dustin E Schones, Louis N Manganas, William M Keyes

Cell Cycle· September 2007

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p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors.
William M Keyes, Hannes Vogel, Maranke I Koster, Xuecui Guo, Yi Qi

Proc Natl Acad Sci U S A· May 2006

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p63: a new link between senescence and aging.
William M Keyes, Alea A Mills

Cell Cycle· February 2006

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p63 is an essential proapoptotic protein during neural development.
W Bradley Jacobs, Gregory Govoni, Daniel Ho, Jasvinder K Atwal, Fanie Barnabe-Heider, William M Keyes

Neuron· December 2005

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p63 deficiency activates a program of cellular senescence and leads to accelerated aging.
William M Keyes, Ying Wu, Hannes Vogel, Xuecui Guo, Scott W Lowe

Genes Dev· September 2005

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Expression and function of bone morphogenetic proteins in the development of the embryonic endocardial cushions.
William M Keyes, Cairine Logan, Eve Parker, Esmond J Sanders

Anat Embryol (Berl)· September 2003

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