Publications by authors named "William Markesbery"

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APOε2 and education in cognitively normal older subjects with high levels of AD pathology at autopsy: findings from the Nun Study.
Diego Iacono, Peter Zandi, Myron Gross, William R Markesbery, Olga Pletnikova

Oncotarget· June 2015

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Increased 5S rRNA oxidation in Alzheimer's disease.
Qunxing Ding, Haiyan Zhu, Bing Zhang, Augusto Soriano, Roxanne Burns, William R Markesbery

J Alzheimers Dis· September 2012

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Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer's disease.
A-Ryeong Gwon, Jong-Sung Park, Thiruma V Arumugam, Yong-Kook Kwon, Sic L Chan, William R Markesbery

Aging Cell· August 2012

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Elevated 4-hydroxyhexenal in Alzheimer's disease (AD) progression.
Melissa A Bradley, Shuling Xiong-Fister, William R Markesbery, Mark A Lovell

Neurobiol Aging· June 2012

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Understanding dementia prevalence among centenarians.
Leonard W Poon, John L Woodard, L Stephen Miller, Robert Green, Marla Gearing, William Markesbery

J Gerontol A Biol Sci Med Sci· April 2012

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Molecular changes in brain aging and Alzheimer's disease are mirrored in experimentally silenced cortical neuron networks.
Marc Gleichmann, Yongqing Zhang, William H Wood, Kevin G Becker, Mohamed R Mughal, William R Markesbery

Neurobiol Aging· January 2012

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Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study.
Patricia L Kramer, Haiyan Xu, Randall L Woltjer, Shawn K Westaway, David Clark, William R Markesbery

Neurobiol Aging· December 2011

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Proteomic analysis of brain proteins in APP/PS-1 human double mutant knock-in mice with increasing amyloid β-peptide deposition: insights into the effects of in vivo treatment with N-acetylcysteine as a potential therapeutic intervention in mild cognitive impairment and Alzheimer's disease.
Renã A S Robinson, Gururaj Joshi, Quanzhen Huang, Rukhsana Sultana, Austin S Baker, William R Markesbery

Proteomics· November 2011

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Proteomic identification of specifically carbonylated brain proteins in APP(NLh)/APP(NLh) × PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice model of Alzheimer disease as a function of age.
Rukhsana Sultana, Renã A S Robinson, Fabio Di Domenico, Hafiz Mohmmad Abdul, Daret K St Clair, William R Markesbery

J Proteomics· October 2011

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Neuron specific toxicity of oligomeric amyloid-β: role for JUN-kinase and oxidative stress.
Philip J Ebenezer, Adam M Weidner, Harry LeVine, William R Markesbery, M Paul Murphy

J Alzheimers Dis· June 2011

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Redox proteomics analysis of brains from subjects with amnestic mild cognitive impairment compared to brains from subjects with preclinical Alzheimer's disease: insights into memory loss in MCI.
Christopher D Aluise, Renã A S Robinson, Jian Cai, William M Pierce, William R Markesbery

J Alzheimers Dis· May 2011

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Association between male gender and cortical Lewy body pathology in large autopsy series.
Peter T Nelson, Frederick A Schmitt, Gregory A Jicha, Richard J Kryscio, Erin L Abner, William R Markesbery

J Neurol· November 2010

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Potential in vivo amelioration by N-acetyl-L-cysteine of oxidative stress in brain in human double mutant APP/PS-1 knock-in mice: toward therapeutic modulation of mild cognitive impairment.
Quanzhen Huang, Christopher D Aluise, Gururaj Joshi, Rukhsana Sultana, Daret K St Clair, William R Markesbery

J Neurosci Res· September 2010

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Comparison of recruitment efforts targeted at primary care physicians versus the community at large for participation in Alzheimer disease clinical trials.
Sarah A Carr, Roberta Davis, Diane Spencer, Marie Smart, Joanna Hudson, William R Markesbery

Alzheimer Dis Assoc Disord· August 2010

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Neuropathologic alterations in mild cognitive impairment: a review.
William R Markesbery

J Alzheimers Dis· August 2010

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Quantitative changes in the mitochondrial proteome from subjects with mild cognitive impairment, early stage, and late stage Alzheimer's disease.
Bert C Lynn, Jianquan Wang, William R Markesbery, Mark A Lovell

J Alzheimers Dis· August 2010

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Preclinical Alzheimer disease: brain oxidative stress, Abeta peptide and proteomics.
Christopher D Aluise, Renã A Sowell Robinson, Tina L Beckett, M Paul Murphy, Jian Cai, William R Markesbery

Neurobiol Dis· August 2010

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NOX activity is increased in mild cognitive impairment.
Annadora J Bruce-Keller, Sunita Gupta, Taryn E Parrino, Alecia G Knight, Philip J Ebenezer, William R Markesbery

Antioxid Redox Signal· June 2010

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Increased protein hydrophobicity in response to aging and Alzheimer disease.
Kalavathi Dasuri, Philip Ebenezer, Le Zhang, Sun Ok Fernandez-Kim, Annadora J Bruce-Keller, William R Markesbery

Free Radic Biol Med· May 2010

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Age-related loss of phospholipid asymmetry in APP(NLh)/APP(NLh) x PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice: relevance to Alzheimer disease.
Miranda L Bader Lange, Daret St Clair, William R Markesbery, Christa M Studzinski, M Paul Murphy

Neurobiol Dis· April 2010

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Omega-3 fatty acids: potential role in the management of early Alzheimer's disease.
Gregory A Jicha, William R Markesbery

Clin Interv Aging· April 2010

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Low sensitivity in clinical diagnoses of dementia with Lewy bodies.
Peter T Nelson, Gregory A Jicha, Richard J Kryscio, Erin L Abner, Frederick A Schmitt, William R Markesbery

J Neurol· March 2010

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Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain.
Karrie E Grear, I-Fang Ling, James F Simpson, Jennifer L Furman, Christopher R Simmons, William R Markesbery

Mol Neurodegener· November 2009

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Lewy body pathology in normal elderly subjects.
William R Markesbery, Gregory A Jicha, Huaichen Liu, Frederick A Schmitt

J Neuropathol Exp Neurol· July 2009

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Brains with medial temporal lobe neurofibrillary tangles but no neuritic amyloid plaques are a diagnostic dilemma but may have pathogenetic aspects distinct from Alzheimer disease.
Peter T Nelson, Erin L Abner, Frederick A Schmitt, Richard J Kryscio, Gregory A Jicha, William R Markesbery

J Neuropathol Exp Neurol· July 2009

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