Publications by authors named "Wim Floren"

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Is the forming of neuronal network activity in human-induced pluripotent stem cells important for the detection of drug-induced seizure risks?
Mohamed Kreir, Wim Floren, Rafaela Policarpo, An De Bondt, Ilse Van den Wyngaert

Eur J Pharmacol· September 2022

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Identification of a series of substituted 2-piperazinyl-5-pyrimidylhydroxamic acids as potent histone deacetylase inhibitors.
Patrick Angibaud, Kristof Van Emelen, Laurence Decrane, Sven van Brandt, Peter Ten Holte, Wim Floren

Bioorg Med Chem Lett· January 2010

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JNJ-26481585, a novel "second-generation" oral histone deacetylase inhibitor, shows broad-spectrum preclinical antitumoral activity.
Janine Arts, Peter King, Ann Mariën, Wim Floren, Ann Beliën

Clin Cancer Res· November 2009

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Real-time gene expression analysis in human xenografts for evaluation of histone deacetylase inhibitors.
Ann Beliën, Stefanie De Schepper, Wim Floren, Boud Janssens, Ann Mariën

Mol Cancer Ther· September 2006

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Discovery of pyrimidyl-5-hydroxamic acids as new potent histone deacetylase inhibitors.
Patrick Angibaud, Janine Arts, Kristof Van Emelen, Virginie Poncelet, Isabelle Pilatte, Wim Floren

Eur J Med Chem· June 2005

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Targeted delivery of RNA-cleaving DNA enzyme (DNAzyme) to tumor tissue by transferrin-modified, cyclodextrin-based particles.
Suzie H Pun, Frederik Tack, Nathalie C Bellocq, Jianjun Cheng, Brendan H Grubbs, Wim Floren

Cancer Biol Ther· July 2004

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