Publications by authors named "Winfried Edelmann"

Claim this Profile
M
Mismatch repair deficiency drives malignant progression and alters the tumor immune microenvironment in glioblastoma models.
Montserrat Puigdelloses Vallcorba, Nishant Soni, Seung-Won Choi, Kavita Rawat, Tanvi Joshi, Winfried Edelmann

J Clin Invest· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Divergent accumulation patterns of SNVs and INDELs reveal negative selection in noncancerous cells.
Lei Zhang, Moonsook Lee, Xiaoxiao Hao, Xiao Ma, Chuwei Xia, Winfried Edelmann

Innovation (Camb)· October 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
DNA2 and MSH2 cooperatively repair stabilized G4 and allow efficient telomere replication.
Anthony Fernandez, Tingting Zhou, Yi Lei, Nian Liu, Steven Esworthy, Winfried Edelmann

Nat Commun· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Emerging Strategies for Targeting Angiogenesis and the Tumor Microenvironment in Gastrointestinal Malignancies: A Comprehensive Review.
Emily Nghiem, Briana Friedman, Nityanand Srivastava, Andrew Takchi, Mahshid Mohammadi, Winfried Edelmann

Pharmaceuticals (Basel)· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibition of histone methyltransferase EZH2 for immune interception of colorectal cancer in Lynch syndrome.
Charles M Bowen, Fahriye Duzagac, Abel Martel-Martel, Laura Reyes-Uribe, Mahira Zaheer, Winfried Edelmann

JCI Insight· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A CAG repeat threshold for therapeutics targeting somatic instability in Huntington's disease.
Sarah G Aldous, Edward J Smith, Christian Landles, Georgina F Osborne, Maria Cañibano-Pico, Winfried Edelmann

Brain· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Negative Selection Allows DNA Mismatch Repair-Deficient Mouse Fibroblasts to Tolerate High Levels of Somatic Mutations.
Lei Zhang, Moonsook Lee, Xiaoxiao Hao, Joseph Ehlert, Zhongxuan Chi, Winfried Edelmann

bioRxiv· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Combined inhibition of MTAP and MAT2a mimics synthetic lethality in tumor models via PRMT5 inhibition.
Gabriel T Bedard, Nord Gilaj, Karina Peregrina, Isabella Brew, Elena Tosti, Winfried Edelmann

J Biol Chem· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
V
Vaccination and Microbiota Manipulation Approaches for Colon Cancer Prevention in Rodent Models.
Elena Tosti, Nityanand Srivastava, Winfried Edelmann

Cancer Prev Res (Phila)· August 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Blockade of the immunosuppressive KIR2DL5/PVR pathway elicits potent human NK cell-mediated antitumor immunity.
Xiaoxin Ren, Mou Peng, Peng Xing, Yao Wei, Phillip M Galbo, Winfried Edelmann

J Clin Invest· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Loss of MMR and TGFBR2 Increases the Susceptibility to Microbiota-Dependent Inflammation-Associated Colon Cancer.
Elena Tosti, Ana S Almeida, Tam T T Tran, Mariel Barbachan E Silva, Pilib Ó Broin, Winfried Edelmann

Cell Mol Gastroenterol Hepatol· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in Exo1D173A mice.
Shanzhi Wang, Kyeryoung Lee, Stephen Gray, Yongwei Zhang, Catherine Tang, Winfried Edelmann

Nucleic Acids Res· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Genome Replication Is Associated With Release of Immunogenic DNA Waste.
Nadja Schubert, Tina Schumann, Elena Daum, Karolin Flade, Yan Ge, Winfried Edelmann

Front Immunol· June 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Recurrent Frameshift Neoantigen Vaccine Elicits Protective Immunity With Reduced Tumor Burden and Improved Overall Survival in a Lynch Syndrome Mouse Model.
Johannes Gebert, Ozkan Gelincik, Mine Oezcan-Wahlbrink, Jason D Marshall, Alejandro Hernandez-Sanchez, Winfried Edelmann

Gastroenterology· October 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Transcriptomic Landscape of Mismatch Repair-Deficient Intestinal Stem Cells.
Prashant V Bommi, Charles M Bowen, Laura Reyes-Uribe, Wenhui Wu, Hiroyuki Katayama, Winfried Edelmann

Cancer Res· May 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
H1 histones control the epigenetic landscape by local chromatin compaction.
Michael A Willcockson, Sean E Healton, Cary N Weiss, Boris A Bartholdy, Yair Botbol, Winfried Edelmann

Nature· January 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Corrigendum to "Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression" [Dev. Biol. Vol.377 (2013) 213-223].
Adriana C Ene, Stephanie Park, Winfried Edelmann, Teruko Taketo

Dev Biol· September 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Molecular structures and mechanisms of DNA break processing in mouse meiosis.
Shintaro Yamada, Anjali Gupta Hinch, Hisashi Kamido, Yongwei Zhang, Winfried Edelmann

Genes Dev· June 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Homozygous hydroxymethylbilane synthase knock-in mice provide pathogenic insights into the severe neurological impairments present in human homozygous dominant acute intermittent porphyria.
Makiko Yasuda, Lin Gan, Brenden Chen, Chunli Yu, Jinglan Zhang, Winfried Edelmann

Hum Mol Genet· June 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mutation of the ATPase Domain of MutS Homolog-5 (MSH5) Reveals a Requirement for a Functional MutSγ Complex for All Crossovers in Mammalian Meiosis.
Carolyn R Milano, J Kim Holloway, Yongwei Zhang, Bo Jin, Cameron Smith, Winfried Edelmann

G3 (Bethesda)· June 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MutLγ promotes repeat expansion in a Fragile X mouse model while EXO1 is protective.
Xiaonan Zhao, Yongwei Zhang, Kenneth Wilkins, Winfried Edelmann, Karen Usdin

PLoS Genet· October 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
EXO1 suppresses double-strand break induced homologous recombination between diverged sequences in mammalian cells.
Chun-Chin Chen, Elena Avdievich, Yongwei Zhang, Yu Zhang, Kaichun Wei, Winfried Edelmann

DNA Repair (Amst)· September 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair.
Sohail Jahid, Jian Sun, Ozkan Gelincik, Pedro Blecua, Winfried Edelmann

Oncotarget· September 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The ISWI ATPase Smarca5 (Snf2h) Is Required for Proliferation and Differentiation of Hematopoietic Stem and Progenitor Cells.
Juraj Kokavec, Tomas Zikmund, Filipp Savvulidi, Vojtech Kulvait, Winfried Edelmann

Stem Cells· June 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Novel Chemotherapeutic Agent to Treat Tumors with DNA Mismatch Repair Deficiencies.
Yongliang Zhang, Jennifer T Fox, Young-Un Park, Gene Elliott, Ganesha Rai, Winfried Edelmann

Cancer Res· July 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis