Publications by authors named "Xiang-Ding Chen"

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Identification of osteoarthritis-related genes and potential drugs based on single cell RNA-seq data.
Ning Wang, Kun Liu, Jia-Li Li, Wei-Wei Pang, Fu-Rong Zhang, Xiang-Ding Chen

Mol Med· November 2025

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Identification of Immune Hub Genes in Obese Postmenopausal Women Using Microarray and Single-Cell RNA Seq Data.
Fu-Rong Zhang, Xuan Lu, Jia-Li Li, Yu-Xin Li, Wei-Wei Pang, Xiang-Ding Chen

Genes (Basel)· June 2025

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Aurantio‑obtusin regulates lipogenesis and ferroptosis of liver cancer cells through inhibiting SCD1 and sensitizing RSL3.
Wen Liu, Jun Deng, Xiao-Jun Tao, Ya Peng, Xiang-Ding Chen

Int J Oncol· October 2024

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Mendelian randomization and transcriptome analysis identified immune-related biomarkers for osteoarthritis.
Wei-Wei Pang, Yi-Sheng Cai, Chong Cao, Fu-Rong Zhang, Qin Zeng, Xiang-Ding Chen

Front Immunol· April 2024

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Functional Enrichment Analysis Identifying Regulatory Information Associated with Human Fracture.
Xiang-He Meng, Zhen Liu, Xiang-Ding Chen, Ai-Min Deng, Zeng-Hui Mao

Calcif Tissue Int· September 2023

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Dissection of Cellular Communication between Human Primary Osteoblasts and Bone Marrow Mesenchymal Stem Cells in Osteoarthritis at Single-Cell Resolution.
Ying Liu, Yan Chen, Xiao-Hua Li, Chong Cao, Hui-Xi Zhang, Yu Chen, Liang Cheng, Xiang-Ding Chen

Int J Stem Cells· August 2023

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A Mendelian randomization study for drug repurposing reveals bezafibrate and fenofibric acid as potential osteoporosis treatments.
Xiao-Hua Li, Wei-Wei Pang, Yue Zhang, Dan-Yang Liu, Qiao-Rong Yi, Xiang-Ding Chen

Front Pharmacol· July 2023

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Imputation of Human Primary Osteoblast Single Cell RNA-Seq Data Identified Three Novel Osteoblastic Subtypes.
Hui-Xi Zhang, Chong Cao, Xiao-Hua Li, Yan Chen, Yue Zhang, Yu Chen, Liang Cheng, Xiang-Ding Chen

Front Biosci (Landmark Ed)· October 2022

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Genome-wide meta-analysis of alcohol use disorder in East Asians.
Hang Zhou, Rasmon Kalayasiri, Yan Sun, Yaira Z Nuñez, Hong-Wen Deng, Xiang-Ding Chen

Neuropsychopharmacology· September 2022

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Identification of novel pleiotropic gene for bone mineral density and lean mass using the cFDR method.
Li-Jun Tan, Xiao-Hua Li, Gai-Gai Li, Yuan Hu, Xiang-Ding Chen

Ann Hum Genet· November 2021

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Identification of novel variants associated with osteoporosis, type 2 diabetes and potentially pleiotropic loci using pleiotropic cFDR method.
Yuan Hu, Li-Jun Tan, Xiang-Ding Chen, Jonathan Greenbaum, Hong-Wen Deng

Bone· December 2018

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Genome-wide association study of lncRNA polymorphisms with bone mineral density.
Qin Zeng, Ke-Hao Wu, Kun Liu, Yuan Hu, Xiang-Ding Chen

Ann Hum Genet· September 2018

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Integration of summary data from GWAS and eQTL studies identified novel causal BMD genes with functional predictions.
Xiang-He Meng, Xiang-Ding Chen, Jonathan Greenbaum, Qin Zeng, Sheng-Lan You

Bone· August 2018

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Inferring causal relationships between phenotypes using summary statistics from genome-wide association studies.
Xiang-He Meng, Hui Shen, Xiang-Ding Chen, Hong-Mei Xiao, Hong-Wen Deng

Hum Genet· March 2018

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Identification of Novel Potentially Pleiotropic Variants Associated With Osteoporosis and Obesity Using the cFDR Method.
Yuan Hu, Li-Jun Tan, Xiang-Ding Chen, Zhen Liu, Shi-Shi Min

J Clin Endocrinol Metab· January 2018

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Bivariate genome-wide association analyses identified genetic pleiotropic effects for bone mineral density and alcohol drinking in Caucasians.
Shan Lu, Lan-Juan Zhao, Xiang-Ding Chen, Christopher J Papasian, Ke-Hao Wu

J Bone Miner Metab· November 2017

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Whole-exome sequencing in amyotrophic lateral sclerosis suggests NEK1 is a risk gene in Chinese.
Jacob Gratten, Qiongyi Zhao, Beben Benyamin, Fleur Garton, Ji He, Lu Chen, Xiang-Ding Chen

Genome Med· November 2017

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Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis.
Beben Benyamin, Ji He, Qiongyi Zhao, Jacob Gratten, Fleur Garton, Lu Chen, Xiang-Ding Chen

Nat Commun· September 2017

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Functional relevance for associations between osteoporosis and genetic variants.
Kun Liu, Li-Jun Tan, Peng Wang, Xiang-Ding Chen, Li-Hua Zhu

PLoS One· August 2017

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Multiple analyses indicate the specific association of NR1I3, C6 and TNN with low hip BMD risk.
Ying-Ying Han, Lan-Juan Zhao, Yong Lin, Hao He, Qing Tian, Xiang-Ding Chen

J Genet Genomics· June 2017

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SNP-SNP interactions between WNT4 and WNT5A were associated with obesity related traits in Han Chinese Population.
Shan-Shan Dong, Wei-Xin Hu, Tie-Lin Yang, Xiao-Feng Chen, Han Yan, Xiang-Ding Chen

Sci Rep· March 2017

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Integrating Epigenomic Elements and GWASs Identifies BDNF Gene Affecting Bone Mineral Density and Osteoporotic Fracture Risk.
Yan Guo, Shan-Shan Dong, Xiao-Feng Chen, Ying-Aisha Jing, Man Yang, Xiang-Ding Chen

Sci Rep· July 2016

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Integrative Analysis of Transcriptomic and Epigenomic Data to Reveal Regulation Patterns for BMD Variation.
Ji-Gang Zhang, Li-Jun Tan, Chao Xu, Hao He, Qing Tian, Xiang-Ding Chen

PLoS One· May 2016

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Identification of IDUA and WNT16 Phosphorylation-Related Non-Synonymous Polymorphisms for Bone Mineral Density in Meta-Analyses of Genome-Wide Association Studies.
Tianhua Niu, Ning Liu, Xun Yu, Ming Zhao, Hyung Jin Choi, Xiang-Ding Chen

J Bone Miner Res· February 2016

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Bivariate Genome-Wide Association Study Implicates ATP6V1G1 as a Novel Pleiotropic Locus Underlying Osteoporosis and Age at Menarche.
Li-Jun Tan, Zhuo-Er Wang, Ke-Hao Wu, Xiang-Ding Chen, Hu Zhu

J Clin Endocrinol Metab· November 2015

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