Publications by authors named "Xiangdong Le"

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Development of a rational strategy for integration of lactate dehydrogenase A suppression into therapeutic algorithms for head and neck cancer.
Yunyun Chen, Anastasios Maniakas, Lin Tan, Meng Cui, Xiangdong Le

Br J Cancer· May 2021

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Regulation of receptor tyrosine kinases by miRNA: overexpression of miRNA using lentiviral inducible expression vectors.
XiangDong Le, Andrew T Huang, Yunyun Chen, Stephen Y Lai

Methods Mol Biol· June 2015

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Dysregulated expression of FOXM1 isoforms drives progression of pancreatic cancer.
Xiangyu Kong, Lei Li, Zhaoshen Li, Xiangdong Le, Chen Huang

Cancer Res· July 2013

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The critical role of dysregulated FOXM1-PLAUR signaling in human colon cancer progression and metastasis.
Dawei Li, Ping Wei, Zhihai Peng, Chen Huang, Huamei Tang, Xiangdong Le

Clin Cancer Res· January 2013

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Dysregulated Krüppel-like factor 4 and vitamin D receptor signaling contribute to progression of hepatocellular carcinoma.
Qi Li, Yong Gao, Zhiliang Jia, Lopa Mishra, Kun Guo, Xiangdong Le

Gastroenterology· September 2012

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Disruption of Klf4 in villin-positive gastric progenitor cells promotes formation and progression of tumors of the antrum in mice.
Qiang Li, Zhiliang Jia, Li Wang, Xiangyu Kong, Qi Li, Xiangdong Le

Gastroenterology· March 2012

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A novel FoxM1-caveolin signaling pathway promotes pancreatic cancer invasion and metastasis.
Chen Huang, Zhengjun Qiu, Liwei Wang, Zhihai Peng, Zhiliang Jia, Xiangdong Le

Cancer Res· February 2012

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Combining betulinic acid and mithramycin a effectively suppresses pancreatic cancer by inhibiting proliferation, invasion, and angiogenesis.
Yong Gao, Zhiliang Jia, Xiangyu Kong, Qiang Li, David Z Chang, Xiangdong Le

Cancer Res· August 2011

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KLF4-mediated negative regulation of IFITM3 expression plays a critical role in colon cancer pathogenesis.
Dawei Li, Zhihai Peng, Huamei Tang, Ping Wei, Xiangyu Kong, Xiangdong Le

Clin Cancer Res· June 2011

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KLF4α up-regulation promotes cell cycle progression and reduces survival time of patients with pancreatic cancer.
Daoyan Wei, Liwei Wang, Masashi Kanai, Zhiliang Jia, Xiangdong Le

Gastroenterology· December 2010

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Modeling liver metastasis using a tumor cell line derived from an enhanced green fluorescent protein transgenic mouse.
Qiang Li, Daoyan Wei, Li Wang, Liwei Wang, Zhiliang Jia, Xiangdong Le

Clin Exp Metastasis· February 2010

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Combined treatment of pancreatic cancer with mithramycin A and tolfenamic acid promotes Sp1 degradation and synergistic antitumor activity.
Zhiliang Jia, Yong Gao, Liwei Wang, Qiang Li, Jun Zhang, Xiangdong Le

Cancer Res· February 2010

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Critical role and regulation of transcription factor FoxM1 in human gastric cancer angiogenesis and progression.
Qiang Li, Nu Zhang, Zhiliang Jia, Xiangdong Le, Bingbing Dai

Cancer Res· April 2009

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Inhibition of the growth and metastasis of human colon cancer by restoration of RUNX3 expression in cancer cells.
Zhihai Peng, Huamei Tang, Xiaoliang Wang, Chongzhi Zhou, Junwei Fan, Xiangdong Le

Int J Oncol· November 2008

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Gene-expression profiling in Chinese patients with colon cancer by coupling experimental and bioinformatic genomewide gene-expression analyses: identification and validation of IFITM3 as a biomarker of early colon carcinogenesis.
Junwei Fan, Zhihai Peng, Chongzhi Zhou, Guoqiang Qiu, Huamei Tang, Xiangdong Le

Cancer· July 2008

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Kruppel-like factor 4 induces p27Kip1 expression in and suppresses the growth and metastasis of human pancreatic cancer cells.
Daoyan Wei, Masahsi Kanai, Zhiliang Jia, Xiangdong Le, Keping Xie

Cancer Res· June 2008

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Therapeutic inhibition of Sp1 expression in growing tumors by mithramycin a correlates directly with potent antiangiogenic effects on human pancreatic cancer.
Ping Yuan, Liwei Wang, Daoyan Wei, Jun Zhang, Zhiliang Jia, Xiangdong Le

Cancer· December 2007

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Molecular basis of the synergistic antiangiogenic activity of bevacizumab and mithramycin A.
Zhiliang Jia, Jun Zhang, Daoyan Wei, Liwei Wang, Ping Yuan, Xiangdong Le

Cancer Res· May 2007

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RUNX3 inhibits the expression of vascular endothelial growth factor and reduces the angiogenesis, growth, and metastasis of human gastric cancer.
Zhihai Peng, Daoyan Wei, Liwei Wang, Huamei Tang, Jun Zhang, Xiangdong Le

Clin Cancer Res· November 2006

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Loss of Krüppel-like factor 4 expression contributes to Sp1 overexpression and human gastric cancer development and progression.
Masashi Kanai, Daoyan Wei, Qiang Li, Zhiliang Jia, Jaffer Ajani, Xiangdong Le

Clin Cancer Res· November 2006

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A high expression level of insulin-like growth factor I receptor is associated with increased expression of transcription factor Sp1 and regional lymph node metastasis of human gastric cancer.
Yixing Jiang, Liwei Wang, Weida Gong, Daoyan Wei, Xiangdong Le

Clin Exp Metastasis· August 2005

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Loss of RUNX3 expression significantly affects the clinical outcome of gastric cancer patients and its restoration causes drastic suppression of tumor growth and metastasis.
Daoyan Wei, Weida Gong, Sang C Oh, Qiang Li, Won Dong Kim, Xiangdong Le

Cancer Res· June 2005

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Nitric oxide synthase II suppresses the growth and metastasis of human cancer regardless of its up-regulation of protumor factors.
Xiangdong Le, Daoyan Wei, Suyun Huang, Jack R Lancaster, Keping Xie

Proc Natl Acad Sci U S A· June 2005

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Transcription factor Sp1 expression is a significant predictor of survival in human gastric cancer.
Liwei Wang, Daoyan Wei, Suyun Huang, Zhihai Peng, Xiangdong Le

Clin Cancer Res· December 2003

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Direct demonstration of negative regulation of tumor growth and metastasis by host-inducible nitric oxide synthase.
Daoyan Wei, Erica L Richardson, Keyi Zhu, Liwei Wang, Xiangdong Le

Cancer Res· July 2003

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