Publications by authors named "Xiangkun Han"

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Oxidative stress-triggered Wnt signaling perturbation characterizes the tipping point of lung adeno-to-squamous transdifferentiation.
Zhaoyuan Fang, Xiangkun Han, Yueqing Chen, Xinyuan Tong, Yun Xue

Signal Transduct Target Ther· January 2023

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Author Correction: Transdifferentiation of lung adenocarcinoma in mice with Lkb1 deficiency to squamous cell carcinoma.
Xiangkun Han, Fuming Li, Zhaoyuan Fang, Yijun Gao, Fei Li, Wenjing Zhang, Lei Zhang

Nat Commun· January 2022

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Author Corrections: VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex.
Wenjing Zhang, Yijun Gao, Peixue Li, Zhubing Shi, Tong Guo, Xiangkun Han, Lei Zhang

Cell Res· October 2021

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Targeting HSPA1A in ARID2-deficient lung adenocarcinoma.
Xue Wang, Yuetong Wang, Zhaoyuan Fang, Hua Wang, Jian Zhang, Longfu Zhang, Xiangkun Han, Zhiqi Zhang, Xin Zhang

Natl Sci Rev· October 2021

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Advances in understanding mechanisms of long-term sperm storage-the soft-shelled turtle model.
Hong Chen, Tengfei Liu, William V Holt, Ping Yang, Linli Zhang, Li Zhang, Xiangkun Han

Histol Histopathol· January 2020

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Keratin 14-high subpopulation mediates lung cancer metastasis potentially through Gkn1 upregulation.
Shun Yao, Hsin-Yi Huang, Xiangkun Han, Yi Ye, Zhen Qin

Oncogene· September 2019

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Branched-Chain Amino Acid Metabolic Reprogramming Orchestrates Drug Resistance to EGFR Tyrosine Kinase Inhibitors.
Yuetong Wang, Jian Zhang, Shengxiang Ren, Dan Sun, Hsin-Yi Huang, Xiangkun Han

Cell Rep· July 2019

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Evidence, Mechanism, and Clinical Relevance of the Transdifferentiation from Lung Adenocarcinoma to Squamous Cell Carcinoma.
Shenda Hou, Shiyu Zhou, Zhen Qin, Liu Yang, Xiangkun Han

Am J Pathol· May 2017

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Evolution from genetics to phenotype: reinterpretation of NSCLC plasticity, heterogeneity, and drug resistance.
Yingjiao Xue, Shenda Hou, Hongbin Ji, Xiangkun Han

Protein Cell· March 2017

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Identification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma.
Fei Li, Zhaoyuan Fang, Jian Zhang, Chen Li, Hongyan Liu, Xiangkun Han, Wenjing Zhang

Cell Res· October 2016

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Squamous Transition of Lung Adenocarcinoma and Drug Resistance.
Shenda Hou, Xiangkun Han, Hongbin Ji

Trends Cancer· September 2016

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Transdifferentiation of lung adenocarcinoma in mice with Lkb1 deficiency to squamous cell carcinoma.
Xiangkun Han, Fuming Li, Zhaoyuan Fang, Yijun Gao, Fei Li, Wenjing Zhang, Lei Zhang

Nat Commun· November 2015

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YAP promotes malignant progression of Lkb1-deficient lung adenocarcinoma through downstream regulation of survivin.
Wenjing Zhang, Yijun Gao, Fuming Li, Xinyuan Tong, Yan Ren, Xiangkun Han, Lei Zhang

Cancer Res· November 2015

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LKB1 Inactivation Elicits a Redox Imbalance to Modulate Non-small Cell Lung Cancer Plasticity and Therapeutic Response.
Fuming Li, Xiangkun Han, Fei Li, Rui Wang, Hui Wang, Wenjing Zhang

Cancer Cell· May 2015

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YAP inhibits squamous transdifferentiation of Lkb1-deficient lung adenocarcinoma through ZEB2-dependent DNp63 repression.
Yijun Gao, Wenjing Zhang, Xiangkun Han, Fuming Li, Xujun Wang, Lei Zhang

Nat Commun· August 2014

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VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex.
Wenjing Zhang, Yijun Gao, Peixue Li, Zhubing Shi, Tong Guo, Xiangkun Han, Lei Zhang

Cell Res· March 2014

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Integrative genomic analysis reveals a high frequency of LKB1 genetic alteration in Chinese lung adenocarcinomas.
Rong Fang, Chao Zheng, Yihua Sun, Xiangkun Han, Bin Gao

J Thorac Oncol· February 2014

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Identification of RET gene fusion by exon array analyses in "pan-negative" lung cancer from never smokers.
Fei Li, Yan Feng, Rong Fang, Zhaoyuan Fang, Jufeng Xia, Xiangkun Han

Cell Res· May 2012

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Spectrum of oncogenic driver mutations in lung adenocarcinomas from East Asian never smokers.
Chenguang Li, Rong Fang, Yihua Sun, Xiangkun Han, Fei Li

PLoS One· April 2012

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Lung adenocarcinomas with HER2-activating mutations are associated with distinct clinical features and HER2/EGFR copy number gains.
Chenguang Li, Yihua Sun, Rong Fang, Xiangkun Han, Xiaoyang Luo, Yang Zhang

J Thorac Oncol· January 2012

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Comprehensive analysis of epidermal growth factor receptor gene status in lung adenocarcinoma.
Chenguang Li, Yihua Sun, Zhaoyuan Fang, Xiangkun Han, Rong Fang, Yang Zhang, Wenjing Zhang

J Thorac Oncol· June 2011

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LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling.
Yijun Gao, Qian Xiao, HuiMin Ma, Li Li, Jun Liu, Xiangkun Han, Junhua Zhang

Proc Natl Acad Sci U S A· November 2010

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Lung adenocarcinoma from East Asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases.
Yihua Sun, Yan Ren, Zhaoyuan Fang, Chenguang Li, Rong Fang, Xiangkun Han

J Clin Oncol· October 2010

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Spectrum of LKB1, EGFR, and KRAS mutations in chinese lung adenocarcinomas.
Bin Gao, Yihua Sun, Junhua Zhang, Yan Ren, Rong Fang, Xiangkun Han

J Thorac Oncol· August 2010

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Comparable rate of EGFR kinase domain mutation in lung adenocarcinomas from Chinese male and female never-smokers.
Yi-hua Sun, Rong Fang, Bin Gao, Xiang-kun Han, Jun-hua Zhang

Acta Pharmacol Sin· May 2010

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