Publications by authors named "Xianping Dong"

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Endosome-ER contact sites in phagophore formation.
Mengnan Xu, Pingping Wang, Xian-Ping Dong

Trends Cell Biol· September 2025

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Targeting TRPML3 inhibits proliferation and invasion, and enhances doxorubicin sensitivity by disrupting lysosomal acidification and mitochondrial function in triple-negative breast cancer.
Gabriela Maria De Abreu Gomes, Mengnan Xu, Alia Kazim Rizvi Syeda, Renee Raudonis, Shekoufeh Almasi, Xianping Dong

Biochim Biophys Acta Mol Cell Res· August 2025

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MCOLN/TRPML channels in the regulation of MTORC1 and autophagy.
Peng Huang, Rose Yang Dong, Pingping Wang, Mengnan Xu, Xue Sun, Xian-Ping Dong

Autophagy· May 2024

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TRPML3/BK complex promotes autophagy and bacterial clearance by providing a positive feedback regulation of mTOR via PI3P.
Mengnan Xu, Xi Zoë Zhong, Peng Huang, Dawid Jaślan, Pingping Wang, Xian-Ping Dong

Proc Natl Acad Sci U S A· August 2023

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Lysosomal Potassium Channels.
Peng Huang, Mengnan Xu, Yi Wu, Alia Kazim Rizvi Syeda, Xian-Ping Dong

Handb Exp Pharmacol· April 2023

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Proton-Activated Chloride Channel: Physiology and Disease.
Fanglin Peng, Yi Wu, Xianping Dong, Peng Huang

Front Biosci (Landmark Ed)· January 2023

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Lysosomal potassium channels.
Yi Wu, Mengnan Xu, Pingping Wang, Alia Kazim Rizvi Syeda, Peng Huang, Xian-Ping Dong

Cell Calcium· March 2022

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Lysosomal ATP Transporter SLC17A9 Controls Cell Viability via Regulating Cathepsin D.
Peng Huang, Qi Cao, Mengnan Xu, Xian-Ping Dong

Cells· March 2022

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Lysosomal Calcium Channels in Autophagy and Cancer.
Yi Wu, Peng Huang, Xian-Ping Dong

Cancers (Basel)· March 2021

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Endolysosomal TRPMLs in Cancer.
Mengnan Xu, Xian-Ping Dong

Biomolecules· January 2021

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Multiple facets of TRPML1 in autophagy.
Peng Huang, Mengnan Xu, Yi Wu, Alia Kazim Rizvi Syeda, Xian-Ping Dong

Cell Calcium· June 2020

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A lysosomal K channel regulates large particle phagocytosis by facilitating lysosome Ca release.
Xue Sun, Mengnan Xu, Qi Cao, Peng Huang, Xiaojuan Zhu, Xian-Ping Dong

Sci Rep· January 2020

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VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1.
Mariana I Capurro, Laura K Greenfield, Akriti Prashar, Sunny Xia, Majd Abdullah, Xianping Dong

Nat Microbiol· August 2019

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Lysosomal Ca release channel TRPML1 regulates lysosome size by promoting mTORC1 activity.
Yiming Yang, Mengnan Xu, Xiaojuan Zhu, Jing Yao, Bing Shen, Xian-Ping Dong

Eur J Cell Biol· June 2019

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The lysosomal TRPML1 channel regulates triple negative breast cancer development by promoting mTORC1 and purinergic signaling pathways.
Mengnan Xu, Shekoufeh Almasi, Yiming Yang, Chi Yan, Andra Mihaela Sterea, Xian-Ping Dong

Cell Calcium· May 2019

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A negative feedback regulation of MTORC1 activity by the lysosomal Ca channel MCOLN1 (mucolipin 1) using a CALM (calmodulin)-dependent mechanism.
Xue Sun, Yiming Yang, Xi Zoë Zhong, Qi Cao, Xin-Hong Zhu, Xian-Ping Dong

Autophagy· February 2019

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mTOR signalling: jack-of-all-trades .
Yassine El Hiani, Emmanuel Eroume-A Egom, Xian-Ping Dong

Biochem Cell Biol· February 2019

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Engineering Pichia pastoris for Efficient Production of a Novel Bifunctional Strongylocentrotus purpuratus Invertebrate-Type Lysozyme.
Peng Huang, Jinlei Shi, Qingwen Sun, Xianping Dong, Ning Zhang

Appl Biochem Biotechnol· October 2018

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LYZL6, an acidic, bacteriolytic, human sperm-related protein, plays a role in fertilization.
Peng Huang, Wenshu Li, Zhifang Yang, Ning Zhang, Yixin Xu, Xianping Dong

PLoS One· September 2017

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Netrin-1 promotes glioma growth by activating NF-κB via UNC5A.
Jing-Ying Chen, Xiao-Xiao He, Chi Ma, Xin-Min Wu, Xi-Lin Wan, Xian-Ping Dong, Dong-Xu Liu

Sci Rep· July 2017

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Methods for monitoring Ca and ion channels in the lysosome.
Xi Zoë Zhong, Yiming Yang, Xue Sun, Xian-Ping Dong

Cell Calcium· June 2017

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The lysosomal Ca release channel TRPML1 regulates lysosome size by activating calmodulin.
Qi Cao, Yiming Yang, Xi Zoë Zhong, Xian-Ping Dong

J Biol Chem· May 2017

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Inhibition of Transient Receptor Potential Channel Mucolipin-1 (TRPML1) by Lysosomal Adenosine Involved in Severe Combined Immunodeficiency Diseases.
Xi Zoë Zhong, Yuanjie Zou, Xue Sun, Gaofeng Dong, Qi Cao, Xian-Ping Dong

J Biol Chem· February 2017

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BK channel agonist represents a potential therapeutic approach for lysosomal storage diseases.
Xi Zoë Zhong, Xue Sun, Qi Cao, Gaofeng Dong, Raphael Schiffmann, Xian-Ping Dong

Sci Rep· September 2016

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Activation of lysosomal P2X4 by ATP transported into lysosomes via VNUT/SLC17A9 using V-ATPase generated voltage gradient as the driving force.
Xi Zoë Zhong, Qi Cao, Xue Sun, Xian-Ping Dong

J Physiol· August 2016

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