Publications by authors named "Xiao-Jing Gu"

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Epigenetic Mediating Mechanisms in Parkinson's Disease: The Impact of Educational Attainment on SETD1A Expression.
Kang-Fu Yin, Xiao-Jing Gu, Jing-Mei Yu, Wei-Ming Su, Wen-Jie Yang

Mov Disord· November 2025

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Exploring the Protein-Metabolite Interplay to Discover Novel Drug Targets for Alzheimer's Disease.
Kang-Fu Yin, Xiao-Jing Gu, Zheng Jiang, Wei-Ming Su, Qing-Qing Duan

J Gene Med· September 2025

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Genetically Predict Diet-derived Antioxidants and Risk of Neurodegenerative Diseases Among Individuals of European Descent: A Mendelian Randomization Study.
Qing-Qing Duan, Wei-Ming Su, Xiao-Jing Gu, Jiang Long, Zheng Jiang

Brain Behav· August 2025

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Identification of Potential Causal Genes for Neurodegenerative Diseases by Mitochondria-Related Genome-Wide Mendelian Randomization.
Kang-Fu Yin, Ting Chen, Xiao-Jing Gu, Zheng Jiang, Wei-Ming Su

Mol Neurobiol· March 2025

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Quantifying the split-elbow sign: a comprehensive study in amyotrophic lateral sclerosis.
Sheng-Yi He, Wei-Chen Cai, Wei-Ming Su, Qing-Qing Duan, Zheng Jiang, Xiao-Jing Gu

Front Neurol· December 2024

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Loss of CHCHD2 Stability Coordinates with C1QBP/CHCHD2/CHCHD10 Complex Impairment to Mediate PD-Linked Mitochondrial Dysfunction.
Yan-Lin Ren, Zheng Jiang, Jia-Yi Wang, Qin He, Si-Xu Li, Xiao-Jing Gu

Mol Neurobiol· October 2024

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Discovery and Exploration of Lipid-Modifying Drug Targets for ALS by Mendelian Randomization.
Zheng Jiang, Xiao-Jing Gu, Wei-Ming Su, Qing-Qing Duan, Kang-Fu Yin

Mol Neurobiol· September 2024

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Systematic druggable genome-wide Mendelian randomization identifies therapeutic targets for sarcopenia.
Kang-Fu Yin, Ting Chen, Xiao-Jing Gu, Wei-Ming Su, Zheng Jiang

J Cachexia Sarcopenia Muscle· August 2024

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Causal association and mediating effect of blood biochemical metabolic traits and brain image-derived endophenotypes on Alzheimer's disease.
Kang-Fu Yin, Xiao-Jing Gu, Wei-Ming Su, Ting Chen, Jiang Long

Heliyon· April 2024

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TBK1, a prioritized drug repurposing target for amyotrophic lateral sclerosis: evidence from druggable genome Mendelian randomization and pharmacological verification in vitro.
Qing-Qing Duan, Han Wang, Wei-Ming Su, Xiao-Jing Gu, Xiao-Fei Shen, Guo-Bo Li

BMC Med· March 2024

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Systematic druggable genome-wide Mendelian randomisation identifies therapeutic targets for Alzheimer's disease.
Wei-Ming Su, Xiao-Jing Gu, Meng Dou, Qing-Qing Duan, Zheng Jiang

J Neurol Neurosurg Psychiatry· November 2023

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Factors influencing cognitive function in patients with Huntington's disease from China: A cross-sectional clinical study.
Yang-Fan Cheng, Kun-Cheng Liu, Tian-Mi Yang, Yi Xiao, Qi-Rui Jiang, Xiao-Jing Gu, Jean-Marc Burgunder

Brain Behav· November 2023

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Expanding causal genes for Parkinson's disease via multi-omics analysis.
Xiao-Jing Gu, Wei-Ming Su, Meng Dou, Zheng Jiang, Qing-Qing Duan, Guo-Bo Li

NPJ Parkinsons Dis· October 2023

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Identifying novel genes for amyotrophic lateral sclerosis by integrating human brain proteomes with genome-wide association data.
Xiao-Jing Gu, Wei-Ming Su, Meng Dou, Zheng Jiang, Qing-Qing Duan

J Neurol· August 2023

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Risk factors of amyotrophic lateral sclerosis: a global meta-summary.
Qing-Qing Duan, Zheng Jiang, Wei-Ming Su, Xiao-Jing Gu, Han Wang

Front Neurosci· April 2023

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Signature of miRNAs derived from the circulating exosomes of patients with amyotrophic lateral sclerosis.
Yang-Fan Cheng, Xiao-Jing Gu, Tian-Mi Yang, Qian-Qian Wei, Bei Cao

Front Aging Neurosci· February 2023

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Protective effect of antihypertensive drugs on the risk of Parkinson's disease lacks causal evidence from mendelian randomization.
Zheng Jiang, Xiao-Jing Gu, Wei-Ming Su, Qing-Qing Duan, Yan-Lin Ren

Front Pharmacol· February 2023

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The mutation spectrum of Parkinson-disease-related genes in early-onset Parkinson's disease in ethnic Chinese.
Yong-Ping Chen, Shi-Hui Yu, Guo-Hui Zhang, Yan-Bing Hou, Xiao-Jing Gu

Eur J Neurol· November 2022

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MiR-30e-3p inhibits gastric cancer development by negatively regulating THO complex 2 and PI3K/AKT/mTOR signaling.
Xiao-Jing Gu, Ya-Jun Li, Fang Wang, Ting Ye

World J Gastrointest Oncol· November 2022

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Production of a human iPSC line from an early-onset Parkinson's disease patient with a novel CHCHD2 gene truncated mutation.
Zheng Jiang, Xiao-Jing Gu, Wei-Ming Su, Qing-Qing Duan, Jun-Yu Lin

Stem Cell Res· October 2022

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Role of genetics in amyotrophic lateral sclerosis: a large cohort study in Chinese mainland population.
Yong-Ping Chen, Shi-Hui Yu, Qian-Qian Wei, Bei Cao, Xiao-Jing Gu, Xiao-Yan Guo

J Med Genet· September 2022

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LncRNA GAS5 Suppresses Colorectal Cancer Progress by Target miR-21/LIFR Axis.
Juan Xie, Jing-Jing Wang, Ya-Jun Li, Jia Wu, Xiao-Jing Gu

Evid Based Complement Alternat Med· August 2022

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Genetic factors for survival in amyotrophic lateral sclerosis: an integrated approach combining a systematic review, pairwise and network meta-analysis.
Wei-Ming Su, Xiao-Jing Gu, Qing-Qing Duan, Zheng Jiang, Xia Gao

BMC Med· June 2022

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Enrichment of rare variants of BIN1 but not APOE genes in Chinese patients with Parkinson's disease.
Chun Yu Li, Ru Wei Ou, Yong Ping Chen, Xiao Jing Gu, Qian Qian Wei

J Intern Med· May 2022

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Association Analysis of , and Polymorphisms in Chinese Patients With Parkinson's Disease and Multiple System Atrophy.
Wei-Ming Su, Xiao-Jing Gu, Yan-Bing Hou, Ling-Yu Zhang, Bei Cao

Front Genet· November 2021

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