Publications by authors named "Xiao-Xin Yan"

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Cerebral FURIN deficiency impairs astrocytic lipophagy through ITGAV maturation.
Xiao-Yong Xie, Lu Wang, Shi-Qi Xie, Gui-Feng Zhou, Qi-Xin Wen, Xiao-Xin Yan

Autophagy· December 2025

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Pharmacologic inhibition of PCBP2 biomolecular condensates relieves Alzheimer's disease.
Lu Wang, Xiao-Yong Xie, Qiu-Ling Pan, Jiawei Zhang, Gui-Feng Zhou, Xiao-Xin Yan, Yan-Jiang Wang

Nat Commun· November 2025

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Hydrophilic sp-carbon conjugated co-porphyrin covalent organic frameworks for efficient electrocatalytic oxygen reduction reaction.
Yan-Fang Yao, Yun-Rui Lv, Feng Li, Xin-Yi Huang, Si-Jing Huang, Xin-Yan Xiao, Hai-Yang Liu

Mater Horiz· October 2025

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Rational Design of Pyridinium Styryl Derivatives as PET Tracers for Cardiac Amyloidosis Imaging.
Qian Wang, Jianeng Song, Xiaojun Zhang, Qilei Zhang, Yuying Li, Xiao-Xin Yan

J Med Chem· July 2025

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The Comorbidity of AD and PD: Exploring Clinical, Pathological, and Biomarker Interactions.
Qi-Lei Zhang, Yu Liu, Tian Tu, Xiao-Xin Yan

Aging Dis· June 2025

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Mossy fiber expression of αSMA in human hippocampus and its relevance to brain evolution and neuronal development.
Tian Tu, Xiao-Lu Cai, Zhong-Ping Sun, Chen Yang, Juan Jiang, Yan Wang, Yan Zhang, Xiao-Xin Yan

Sci Rep· May 2025

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Acetylsalicylic Acid Promotes Osteogenic Differentiation of Human Dental Pulp Mesenchymal Stem Cells and Regeneration of Alveolar Bone in Experimental Periodontitis Rats.
Aishi Song, Wei Wang, Yuying Zhang, Peng Zhou, Jiaxing Li, Xiao-Xin Yan

J Tissue Eng Regen Med· April 2025

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In vivo imaging of alkaline phosphatase in lipid metabolic diseases with a photoacoustic probe.
Chun-Pu Mao, Xu-Yang Chen, Jie Han, Ting Jiang, Xiao-Xin Yan

Spectrochim Acta A Mol Biomol Spectrosc· February 2025

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Synthesis and preclinical evaluation of diarylamine derivative as Tau-PET radiotracer for Alzheimer's Disease.
Tianqing Liu, Chao Ren, Wantong Guo, Xiaojun Zhang, Yuying Li, Yan Wang, Xiao-Xin Yan

Eur J Med Chem· January 2025

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Cross-ancestry analysis of brain QTLs enhances interpretation of schizophrenia genome-wide association studies.
Yu Chen, Sihan Liu, Zongyao Ren, Feiran Wang, Qiuman Liang, Yan Xia, Xiao-Xin Yan

Am J Hum Genet· November 2024

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Increased expression of mesencephalic astrocyte-derived neurotrophic factor (MANF) contributes to synapse loss in Alzheimer's disease.
Yiran Zhang, Xiusheng Chen, Laiqiang Chen, Mingting Shao, Wenzhen Zhu, Huiming Yang, Xiao-Xin Yan, Su Yang

Mol Neurodegener· October 2024

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Increased expression of the proapoptotic presenilin associated protein is involved in neuronal tangle formation in human brain.
Chen Yang, Zhong-Ping Sun, Juan Jiang, Xiao-Lu Cai, Yan Wang, Yan Zhang, Xiao-Xin Yan

Sci Rep· October 2024

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Suppressing UBE2N ameliorates Alzheimer's disease pathology through the clearance of amyloid beta.
Chen Zhang, Qingqing Jia, Longhong Zhu, Junqi Hou, Xiang Wang, Su Yang, Xiao-Xin Yan, Weili Yang

Alzheimers Dement· September 2024

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Discovery and Evaluation of Imidazo[2,1-][1,3,4]thiadiazole Derivatives as New Candidates for α-Synuclein PET Imaging.
Qi Zeng, Xiaojun Zhang, Yuying Li, Qilei Zhang, Jiapei Dai, Xiao-Xin Yan

J Med Chem· August 2024

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MFGE8 promotes adult hippocampal neurogenesis in rats following experimental subarachnoid hemorrhage via modifying the integrin β3/Akt signaling pathway.
Zhen-Yan Li, Xian Yang, Ji-Kai Wang, Xiao-Xin Yan, Fei Liu

Cell Death Discov· August 2024

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Screening of [F]Florbetazine for Aβ Plaques and a Head-to-Head Comparison Study with [C]Pittsburgh Compound-B ([C]PiB) in Human Subjects.
Yuying Li, Xiaojun Zhang, Hailong Zhao, Yan Wang, Dandan Zhang, Xiao-Xin Yan, Yanying Sui

ACS Pharmacol Transl Sci· July 2024

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TRIM37 is a primate-specific E3 ligase for Huntingtin and accounts for the striatal degeneration in Huntington's disease.
Yiyang Qin, Laiqiang Chen, Wenzhen Zhu, Jiahong Song, Jingpan Lin, Weili Yang, Xiao-Xin Yan, Su Yang

Sci Adv· May 2024

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Maresin 1 Activates LGR6 to Alleviate Neuroinflammation via the CREB/JMJD3/IRF4 Pathway in a Rat Model of Subarachnoid Hemorrhage.
Zhenyan Li, Wen Yuan, Xian Yang, Juan Jiang, Qi-Lei Zhang, Xiao-Xin Yan

Neuroscience· March 2024

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Brain eQTLs of European, African American, and Asian ancestry improve interpretation of schizophrenia GWAS.
Yu Chen, Sihan Liu, Zongyao Ren, Feiran Wang, Yi Jiang, Yan Xia, Xiao-Xin Yan

medRxiv· February 2024

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Bridging integrator 1 fragment accelerates tau aggregation and propagation by enhancing clathrin-mediated endocytosis in mice.
Xingyu Zhang, Li Zou, Li Tang, Min Xiong, Xiao-Xin Yan

PLoS Biol· January 2024

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Synthesis and Bioevaluation of 2-Styrylquinoxaline Derivatives as Tau-PET Tracers.
Nan Wu, Longfei Zhang, Xiaojun Zhang, Qilei Zhang, Jiaqi Liu, Xiao-Xin Yan

Mol Pharm· November 2023

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TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration.
Li Zhong, Xuan Sheng, Wanbing Wang, Yanzhong Li, Rengong Zhuo, Muyang Chen, Xiao-Xin Yan

Immunity· August 2023

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Hydroxyethyl-Modified Cycloheptatriene-BODIPY Derivatives as Specific Tau Imaging Probes.
Yuying Li, Chuan Tian, Tianxin Xie, Qi-Lei Zhang, Jiaqi Liu, Xiao-Xin Yan

ACS Med Chem Lett· August 2023

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Synthesis and Preclinical Evaluation of 2-(4-[F]Fluorophenyl)imidazo[1,2-h][1,7]naphthyridine ([F]FPND-4): An Aza-Fused Tricyclic Derivative as Positron Emission Tomography Tracer for Neurofibrillary Tangle Imaging.
Tianqing Liu, Yuying Li, Xiaojun Zhang, An Yao, Yan Wang, Xiao-Xin Yan

J Med Chem· July 2023

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β-Microglobulin coaggregates with Aβ and contributes to amyloid pathology and cognitive deficits in Alzheimer's disease model mice.
Yini Zhao, Qiuyang Zheng, Yujuan Hong, Yue Gao, Jiaojiao Hu, Xiao-Xin Yan, Yan-Jiang Wang

Nat Neurosci· July 2023

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