Publications by authors named "Xiaoding Tan"

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Structural basis of nectin-4 recognition by the antibody-drug conjugate 9MW2821.
Peng Fang, Meng You, Haiying Wen, Yuxia Cao, Wei Zhou, Xiaoding Tan

J Biol Chem· December 2025

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Overcoming multidrug resistance in gastrointestinal cancers with a CDH17-targeted ADC conjugated to a DNA topoisomerase inhibitor.
Rui Wang, Peng Fang, Xi Chen, Jiali Ji, Dongan Yu, Xiaoding Tan

Cell Rep Med· July 2025

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Structural and Functional Characterization of Disulfide Bond Isomers of Therapeutic Immunoglobulin G2 Antibody.
Huiting Yue, Meng You, Xiaowei Sun, Xiaoxia Xiao, Meiling Li, Xiaoding Tan

J Med Chem· June 2025

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Development and validation of bioanalytical assays for the quantification of 9MW2821, a nectin-4-targeting antibody-drug conjugate.
Peng Fang, Meng You, Yuxia Cao, Qingjun Feng, Lei Shi, Xiaoding Tan

J Pharm Biomed Anal· September 2024

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Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E-based Antibody-Drug Conjugate for Treatment of Nectin-4-expressing Cancers.
Wei Zhou, Peng Fang, Dongan Yu, Hongyuan Ren, Meng You, Xiaoding Tan

Mol Cancer Ther· August 2023

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A HER2-targeted antibody-novel DNA topoisomerase I inhibitor conjugate induces durable adaptive antitumor immunity by activating dendritic cells.
Xiaoding Tan, Peng Fang, Kaiying Li, Meng You, Yuxia Cao

MAbs· June 2023

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Study on the Heterogeneity of T-DM1 and the Analysis of the Unconjugated Linker Structure under a Stable Conjugation Process.
Guanghao Wu, Yanbo Gao, Datao Liu, Xiaoding Tan, Lide Hu

ACS Omega· May 2019

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