Publications by authors named "Xiaolin Tu"

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Engineering a Wnt-activated osteomimetic microenvironment with iPSC-derived MSCs for synergistic bone regeneration, angiogenesis, and neurogenesis.
Qiqi Bu, Hao Bai, Minjie Ruan, Lu Gao, Liuqing Wang, Xiaolin Tu

Biomaterials· January 2026

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Inhibition of ferroptosis rescues BMP osteogenic differentiation impaired by iron overload in the osteoporotic microenvironment.
Xun Tang, Mengfan Yang, Yujiao Liu, Hongjun Zhang, Xiang Hong, Xiaolin Tu

Cell Signal· December 2025

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Osteocytes Produces RANKL Via Wnt-TGFβ Signaling Axis for Osteoclastogenesis.
Yujiao Liu, Lizhou Zhao, Molin Li, Weimin Gong, Xiaofang Wang, Xiaolin Tu

Int J Biol Sci· October 2025

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BMP9 attenuates microgravity-related disuse osteoporosis by modulating TGFβ and BMP signaling.
Haoyang Zhao, Mengfan Yang, Yujiao Liu, Xiaolin Tu, Gaohai Shao

NPJ Microgravity· August 2025

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The potential key genes within focal adhesion that regulate mesenchymal stem cells osteogenesis or adipogenesis in microgravity related disuse osteoporosis: an integrated analysis.
Haoyang Zhao, Xiaolin Tu

Front Endocrinol (Lausanne)· May 2025

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Establishing stable and highly osteogenic hiPSC-derived MSCs for 3D-printed bone graft through microenvironment modulation by CHIR99021-treated osteocytes.
Qiuling Guo, Jingjing Chen, Qiqi Bu, Jinling Zhang, Minjie Ruan, Xiaolin Tu

Mater Today Bio· June 2024

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The Osteocyte with SB216763-Activated Canonical Wnt Signaling Constructs a Multifunctional 4D Intelligent Osteogenic Module.
Jinling Zhang, Ying Zhang, Jiafeng Chen, Weimin Gong, Xiaolin Tu

Biomolecules· March 2024

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Sustained release of a highly specific GSK3β inhibitor SB216763 in the PCL scaffold creates an osteogenic niche for osteogenesis, anti-adipogenesis, and potential angiogenesis.
Weimin Gong, Molin Li, Lizhou Zhao, Pengtao Wang, Xiaofang Wang, Xiaolin Tu

Front Bioeng Biotechnol· July 2023

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A novel decellularized matrix of Wnt signaling-activated osteocytes accelerates the repair of critical-sized parietal bone defects with osteoclastogenesis, angiogenesis, and neurogenesis.
Xiaofang Wang, Yufei Ma, Jie Chen, Yujiao Liu, Guangliang Liu, Xiaolin Tu

Bioact Mater· March 2023

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CHIR99021-Treated Osteocytes with Wnt Activation in 3D-Printed Module Form an Osteogenic Microenvironment for Enhanced Osteogenesis and Vasculogenesis.
Yisheng Luo, Yangxi Liu, Bo Wang, Xiaolin Tu

Int J Mol Sci· March 2023

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Promotes MSCs Senescence by Inducing Plasma Membrane Depolarization and Increasing Ca Influx.
Molin Li, Weimin Gong, Jie Chen, Yining Zhang, Yufei Ma, Xiaolin Tu

Int J Mol Sci· February 2023

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Activating Wnt/β-Catenin Signaling in Osteocytes Promotes Osteogenic Differentiation of BMSCs through BMP-7.
Yining Zhang, Yixin Zhao, Zhengsong Xie, Molin Li, Yujiao Liu, Xiaolin Tu

Int J Mol Sci· December 2022

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[Activation of Notch signaling in bone marrow stromal cells promotes osteogenesis in mice in vitro].
Xinyu Liu, Cen Luo, Xiaolin Tu

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi· December 2022

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Canonical Wnt signaling works downstream of iron overload to prevent ferroptosis from damaging osteoblast differentiation.
Cen Luo, Wenjuan Xu, Xun Tang, Xinyu Liu, Yu Cheng, Xiaolin Tu

Free Radic Biol Med· August 2022

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A Highly Selective GSK-3β Inhibitor CHIR99021 Promotes Osteogenesis by Activating Canonical and Autophagy-Mediated Wnt Signaling.
Bo Wang, Saima Khan, Pengtao Wang, Xiaofang Wang, Yangxi Liu, Xiaolin Tu

Front Endocrinol (Lausanne)· August 2022

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Functionalized 3D-Printed ST2/Gelatin Methacryloyl/Polcaprolactone Scaffolds for Enhancing Bone Regeneration with Vascularization.
Guangliang Liu, Jie Chen, Xiaofang Wang, Yujiao Liu, Yufei Ma, Xiaolin Tu

Int J Mol Sci· July 2022

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The Notch pathway regulates the bone gain induced by PTH anabolic signaling.
Jesus Delgado-Calle, Kevin McAndrews, Gerald Wu, Ashley L Orr, Adam Ferrari, Xiaolin Tu

FASEB J· March 2022

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The Osteocyte Stimulated by Wnt Agonist SKL2001 Is a Safe Osteogenic Niche Improving Bioactivities in a Polycaprolactone and Cell Integrated 3D Module.
Yangxi Liu, Xiaojie Ruan, Jun Li, Bo Wang, Jie Chen, Xiaolin Tu

Cells· February 2022

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TNFAIP3 ameliorates the degeneration of inflammatory human nucleus pulposus cells by inhibiting mTOR signaling and promoting autophagy.
Jie Chen, Yufei Ma, Zhijie Yang, Haiyang Lan, Guangliang Liu, Xiaolin Tu

Aging (Albany NY)· November 2020

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In vivo evaluation of porous nanohydroxyapatite/polyamide 66 struts in a goat cervical fusion model.
Xi Liang, Feilong Li, Xuan Gong, Junchao Li, Shijie Yin, Xiaolin Tu

Sci Rep· June 2020

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Differentiation of Neural Crest Stem Cells in Response to Matrix Stiffness and TGF-β1 in Vascular Regeneration.
Xian Li, Rong Xu, Xiaolin Tu, Randall Raphael R Janairo, George Kwong

Stem Cells Dev· February 2020

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[All-trans retinoic acid and vascular endothelial growth factor induced the directional osteogenic differentiation of mouse embryonic fibroblasts].
Wei Feng, Xiaolin Tu

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi· February 2020

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Outcome after a new porous tantalum rod implantation for treatment of early-stage femoral head osteonecrosis.
Wei Huang, Xuan Gong, Steve Sandiford, Xiaoqiang He, Feilong Li, Xiaolin Tu

Ann Transl Med· September 2019

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Control of Bone Anabolism in Response to Mechanical Loading and PTH by Distinct Mechanisms Downstream of the PTH Receptor.
Jesus Delgado-Calle, Xiaolin Tu, Rafael Pacheco-Costa, Kevin McAndrews, Rachel Edwards

J Bone Miner Res· March 2017

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In vitro and in vivo biocompatibility and osteogenesis of graphene-reinforced nanohydroxyapatite polyamide66 ternary biocomposite as orthopedic implant material.
Shiyang Zhang, Qiming Yang, Weikang Zhao, Bo Qiao, Hongwang Cui, Xiaolin Tu

Int J Nanomedicine· February 2017

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