Publications by authors named "Xiaoting Gu"

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Supramolecular copolymerized peptide self-assembly enables in situ reprogramming of tumor-associated macrophages to potentiate mild photothermal immunotherapy of cold tumors.
Yuanzhao Mao, Xiaoting Gu, Yitong Yu, Shuang Tian, Yueyuan Liu

Acta Biomater· January 2026

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Intratracheal instillation of chitosan-coated formononetin-loaded porous microspheres prolongs lung retention and improves the treatment in bleomycin-induced pulmonary fibrosis.
Conglu Zhao, Liyuan Ji, Xiaoting Wang, Jia Zhang, Xiang Xu, Songtao Gu, Xiaoting Gu

Eur J Pharm Sci· December 2025

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A magnetic nanoparticles-based ligand fishing method coupled with parallel artificial membrane permeability assay for rapid discovery and analysis of GSNO reductase inhibitors with good membrane permeability from Salvia miltiorrhiza Bunge.
Chaoyue Zheng, Keran Li, Xiaoyu Ai, Liuyao Xie, Hongrong Lu, Xiaoting Gu

Int J Biol Macromol· December 2025

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Remdesivir alleviates inflammation and tissue damage in experimental colitis via AnxA5 Signaling.
Hailong Li, Ying Yang, Jinhe Li, Yayue Hu, Ruiqi Mao, Xiaoting Gu

Int Immunopharmacol· December 2025

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Erratum to "Intratracheal instillation of chitosan-coated formononetin-loaded porous microspheres prolongs lung retention and improves the treatment" [European Journal of Pharmaceutical Sciences. 2025 Dec 1;215:107347].
Conglu Zhao, Liyuan Ji, Xiaoting Wang, Jia Zhang, Xiang Xu, Songtao Gu, Xiaoting Gu

Eur J Pharm Sci· December 2025

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Translational Research on the Oral Delivery of the Cytotoxic PROTAC Molecule via Tumor-Targeting Prodrug Strategy for Triple-Negative Breast Cancer Treatment.
Huayu Hu, Yubo Wang, Mengmeng Wang, Zixuan Zhang, Xiaoting Gu, Guang Yang

J Med Chem· October 2025

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The Genetic and Embryo-Fetal Developmental Toxicity Profile of the Novel Transgelin Agonist Deg-AZM: Ames, Micronucleus, Chromosomal Aberration, and Rat EFD Studies.
Xiaoting Gu, Ying Xu, Nannan Liu, Keran Li, Xiaoting Wang

Biomedicines· October 2025

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Transplacental transfer of metformin and interaction of metformin with the uptake transporters of placental trophoblast cells.
Xiaoting Gu, Yutian Cai, Chaoyue Zheng, Keran Li, Shuwen Zhu

Eur J Pharm Sci· September 2025

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Correction: Miglustat ameliorates isoproterenol-induced cardiac fibrosis via targeting UGCG.
Jing Liu, Wenqi Li, Ran Jiao, Zhigang Liu, Tiantian Zhang, Xiaoting Gu

Mol Med· September 2025

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Preclinical Safety Profile of Deg-AZM, a Clinical-Stage New Transgelin Agonist: hERG Inhibition Study In Vitro, Cardiovascular-Respiratory Pharmacology, and Single/Repeated-Dose Toxicity in Beagle Dogs.
Xiaoting Gu, Xiaohe Li, Hailong Li, Nannan Liu, Ying Xu

Biomedicines· September 2025

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PAR1 inhibition sensitizes HPV-negative HNSCC cells to ferroptosis through inhibition of the STAT3-mediated regulation of iron and lipid metabolic pathways.
Jiao Tian, Chaoge Liu, Bing Li, Ning Hu, Xiaoting Gu

Oncogene· August 2025

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Bergenin and vitexin delivery platform using mouse lung fibroblasts-derived exosomes for bleomycin-induced pulmonary fibrosis therapy.
Yao Sun, Shihao Cai, Hongting Liu, Conglu Zhao, Xiang Xu, Aiguo Xu, Xiaoting Gu

Int J Pharm· August 2025

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Oleuropein Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice by Targeting TGF-β1 Signaling Pathway.
Liang Zhang, Zhigang Liu, Yayue Hu, Xueze Liu, Zhongyi Yang, Xiaoting Gu

Biomolecules· August 2025

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Corrigendum to "Baricitinib alleviates cardiac fibrosis and inflammation induced by chronic sympathetic activation" [Int. Immunopharmacol. 140 (2024) 112894].
Wenqi Li, Jing Liu, Ran Jiao, Zhigang Liu, Tiantian Zhang, Xiaoting Gu

Int Immunopharmacol· July 2025

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Author Correction: Daidzein alleviates skin fibrosis by suppressing TGF-β1 signaling pathway via targeting PKM2.
Xiaowei Guo, Wenqi Li, Wei Ma, Yuming Liu, Zhigang Liu, Xiaoting Gu

Sci Rep· July 2025

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Lenalidomide attenuates cardiac fibrosis and inflammation induced by β-adrenergic receptor activation.
Ran Jiao, Wenqi Li, Xiaoting Gu, Jing Liu, Zhigang Liu, Ruimin Gu

Int Immunopharmacol· June 2025

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Deglycosylated azithromycin alleviates cisplatin-evoked constipation in mice by altering host metabolome and gut microbiota composition.
Xiaoting Gu, Shuwen Zhu, Weixue Tian, Xiaohe Li, Yutian Cai

Front Microbiol· May 2025

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A novel strategy for identifying hepatotoxic constituents in traditional Chinese medicine using dose-normalized intracellular accumulation as a cytotoxicity indicator: a case study of Jinlingzi San.
Xiaoting Gu, Hanyang Wang, Keran Li, Cuiting Wu, Xin Di

Front Pharmacol· May 2025

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Macrophage membrane entrapped rapamycin-loaded TPGS/F127 micelles through intratracheal instillation for enhanced drug delivery and therapy to lung cancer with pulmonary fibrosis.
Hongting Liu, Shihao Cai, Yao Sun, Conglu Zhao, Xiang Xu, Songtao Gu, Qingguo Di, Xiaoting Gu

Int J Pharm· April 2025

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Formononetin-Loaded PLGA Large Porous Microparticles via Intratracheal Instillation for Bleomycin-Induced Pulmonary Fibrosis Treatment.
Hongting Liu, Yao Sun, Shihao Cai, Conglu Zhao, Xiang Xu, Aiguo Xu, Xiaoting Gu

AAPS PharmSciTech· April 2025

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Daidzein alleviates skin fibrosis by suppressing TGF-β1 signaling pathway via targeting PKM2.
Xiaowei Guo, Wenqi Li, Wei Ma, Yuming Liu, Zhigang Liu, Xiaoting Gu

Sci Rep· March 2025

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Treatment of Bleomycin-induced Pulmonary Fibrosis by Intratracheal Instillation Administration of Ellagic Acid-Loaded Chitosan Nanoparticles.
Zhilin Luo, Yao Sun, Shihao Cai, Hongting Liu, Conglu Zhao, Aiguo Xu, Xiaoting Gu

AAPS PharmSciTech· March 2025

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Miglustat ameliorates isoproterenol-induced cardiac fibrosis via targeting UGCG.
Jing Liu, Wenqi Li, Ran Jiao, Zhigang Liu, Tiantian Zhang, Xiaoting Gu

Mol Med· February 2025

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PK-PD relationship of poorly absorbable active ingredients from traditional Chinese medicines explaining by metabolic enzyme of gut microbiota: A case study of Dehydrocorydaline.
Xiaoting Gu, Yutian Cai, Chaoyue Zheng, Liuyao Xie, Linyi Zhang

J Pharm Biomed Anal· January 2025

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The metabolic pathway of Deg-AZM and investigations into the contribution of drug metabolizing enzymes and drug transporters in the drug interactions of Deg-AZM, a clinical-stage new transgelin agonist.
Xiaoting Gu, Xiaohe Li, Weixue Tian, Chaoyue Zheng, Yutian Cai

Front Pharmacol· January 2025

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