Publications by authors named "Xin-Lin Lei"

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TOPO-seq reveals DNA topology-induced off-target activity by Cas9 and base editors.
Min Duan, Pan Gao, Yi-Zhou Zhang, Yu-Long Hu, Lei Zhou, Xin-Lin Lei

Nat Chem Biol· October 2025

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Enhancement of the viability of T cells electroporated with DNA via osmotic dampening of the DNA-sensing cGAS-STING pathway.
Jing An, Chuan-Ping Zhang, Hou-Yuan Qiu, Hong-Xia Zhang, Qiu-Bing Chen, Xin-Lin Lei

Nat Biomed Eng· February 2024

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DNA topology regulates PAM-Cas9 interaction and DNA unwinding to enable near-PAMless cleavage by thermophilic Cas9.
Ya-Jing Shi, Min Duan, Jun-Mei Ding, Fan-Qi Wang, Li-Li Bi, Xin-Lin Lei

Mol Cell· November 2022

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