Publications by authors named "Xinxin Si"

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Integrated Transcriptomic and Metabolomic Analysis Revealed That Tryptophan Metabolism-Related Metabolites Are Biomarkers of Trastuzumab Resistance.
Xinxin Si, Hanzhe Wu, Yiwei Cao, Bangbang Wei, Juan Wei

J Clin Lab Anal· December 2025

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Targeted metabolomics reveals tricarboxylic acid cycle-related metabolites serve as predictive biomarkers for trastuzumab resistance in human epidermal growth factor receptor 2-positive breast cancer.
Ting Yang, Bangbang Wei, Min Wang, Yu Wang, Yiwei Cao, Xinxin Si

J Mol Med (Berl)· November 2025

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Piper longum ameliorates obesity by regulating gut microbiota and promoting adipose thermogenesis.
Long Cheng, Zonghao Liu, Minghong Gan, Huiyang Wang, Xinxin Si

Phytomedicine· November 2025

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The UHPLC-Orbitrap MS/MS and Network Pharmacology Strategies Reveal the Active Antioxidants of Bleeding Sap from Sponge Gourd in Treating Tuberculosis.
Di Zhang, Lu Jiang, Yujiang Dai, Xinxin Si, Huifang Li

Int J Mol Sci· October 2025

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Computer-aided discovery of triazolothiadiazoles as DYRK1A-targeted neuroprotective agents.
Xinxin Si, Yaling Wang, Nianzhuang Qiu, Chenliang Qian, Bochao Yang

RSC Med Chem· July 2025

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Discovery of Novel FtsZ Inhibitors With Antimicrobial Activity by Virtual Screening and In Vitro Biological Evaluation.
Aoqi Luo, Chenliang Qian, Zhenyu Zhang, Jie Xia, Hongwei Jin, Xinxin Si

Chem Biodivers· June 2025

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A scoping review of advancements in machine learning for glaucoma: current trends and future direction.
Jiatong Zhang, Bocheng Tian, Mingke Tian, Xinxin Si, Jiani Li

Front Med (Lausanne)· April 2025

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Identification of ETFDH gene c. 487 + 2 T > A pathogenic variant and mechanisms for polycystic kidney in neonatal onset MADD.
Bijun Zhang, Dongyang Zhang, Feiyue Sun, Xinxin Si, Meng Luan

Orphanet J Rare Dis· March 2025

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Machine Learning-Based Discovery of a Novel Noncovalent MurA Inhibitor as an Antibacterial Agent.
Qingxin Liu, Aoqi Luo, Hongwei Jin, Xinxin Si, Ming Li

Chem Biol Drug Des· March 2025

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Discovery of a novel DYRK1A inhibitor with neuroprotective activity by virtual screening and in vitro biological evaluation.
Xinxin Si, Chenliang Qian, Nianzhuang Qiu, Yaling Wang, Mingli Yao

Mol Divers· February 2025

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Discovery of Metabolic Reprogramming 2-Quinolones as Effective Antimicrobials for MRSA-Infected Wound Therapy.
Lei Xu, Yaling Wang, Sangyu Hu, Yuzhu Pei, Chenliang Qian, Xinxin Si

J Med Chem· February 2025

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Development of a vitrified CRISPR/Cas12b-based assay for rapid genotyping of SNPs without DNA amplification.
Chen Lu, Jiayue Chen, Shengsheng Zhang, Yaru Tian, Xinyu Ying, Xinxin Si

Anal Methods· February 2025

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Expression of ALG8 in hepatocellular carcinoma and its diagnostic and prognostic significance.
Yang Haishen, Feiyu Jiang, Xinxin Si, Dan Sun, Haoran Fei

Scand J Gastroenterol· January 2025

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Identification of SMC2 and SMC4 as prognostic markers in breast cancer through bioinformatics analysis.
Lili Pei, Yu Li, Hao Gu, Siqi Wang, Wenhao Wu, Siyi Fan, Xinxin Si

Clin Transl Oncol· December 2024

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Multi-omic characterization of air pollution effects: Applications of AirSigOmniTWP Hub.
Wei Liu, Tong Liu, Xinxin Si, Jiaxing Liang, Xia Yan

Ecotoxicol Environ Saf· October 2024

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Combined transcriptome and proteome analysis reveals MSN and ARFIP2 as biomarkers for trastuzumab resistance of breast cancer.
Xiao Shi, Yuan Sheng, Haoran Fei, Bangbang Wei, Zhenyu Zhang, Xinxin Si

Breast Cancer Res Treat· August 2024

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Discovery of a novel chemotype as DYRK1A inhibitors against Alzheimer's disease: Computational modeling and biological evaluation.
Nianzhuang Qiu, Chenliang Qian, Tingting Guo, Yaling Wang, Hongwei Jin, Xinxin Si

Int J Biol Macromol· June 2024

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Integrated analysis identified the role of three family members of ARHGAP in pancreatic adenocarcinoma.
Haoran Fei, Xiao Shi, Dan Sun, Haishen Yang, Dali Wang, Xinxin Si

Sci Rep· May 2024

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A landscape of metabolic variation among clinical outcomes of peritoneal dialysis in end-stage renal disease.
Ting Yang, Bangbang Wei, Jing Liu, Xinxin Si, Lulu Wang

Clin Chim Acta· March 2024

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AutoMolDesigner for Antibiotic Discovery: An AI-Based Open-Source Software for Automated Design of Small-Molecule Antibiotics.
Tao Shen, Jiale Guo, Zunsheng Han, Gao Zhang, Qingxin Liu, Xinxin Si

J Chem Inf Model· February 2024

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Identification of a 2-phenylthiazole derivative acetylcholinesterase modulator with in vitro antitumor activity in breast cancer cells.
Xiao Shi, Peng Liu, Yanyan Ma, Mingyuan Li, Zhenyu Zhang, Xinxin Si

Chem Biol Drug Des· January 2024

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Discovery of isatin-β-methyldithiocarbazate derivatives as New Delhi metallo- β-lactamase-1 (NDM-1) inhibitors against NDM-1 producing clinical isolates.
Hongfa Lv, Zihao Zhu, Chenliang Qian, Tianlei Li, Zunsheng Han, Xinxin Si

Biomed Pharmacother· October 2023

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Rapid and accurate genotyping of human SNP rs671 in aldehyde dehydrogenase 2 gene using one-step CRISPR/Cas12b assay without DNA amplification.
Fang Wu, Yong Xue, Yan Wang, Xinxin Si, Xinyue Zhang

Cell Div· August 2023

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Biomaterial-assisted tumor therapy: A brief review of hydroxyapatite nanoparticles and its composites used in bone tumors therapy.
Quan Zhang, Lei Qiang, Yihao Liu, Minjie Fan, Xinxin Si

Front Bioeng Biotechnol· April 2023

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Comprehensive bioinformatics analysis reveals the significance of forkhead box family members in pancreatic adenocarcinoma.
Wei Hu, Mingxu Li, Yan Wang, Chengcheng Zhong, Xinxin Si

Aging (Albany NY)· January 2023

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