Publications by authors named "Xinxiu Li"

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Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer.
Martin Smelik, Daniel Diaz-Roncero Gonzalez, Xiaojing An, Rakesh Heer, Lars Henningsohn, Xinxiu Li, Yelin Zhao

Cancer Res· July 2025

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Digital twins as global learning health and disease models for preventive and personalized medicine.
Xinxiu Li, Joseph Loscalzo, A K M Firoj Mahmud, Dina Mansour Aly, Andrey Rzhetsky

Genome Med· February 2025

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Proteogenomic analysis reveals Arp 2/3 complex as a common molecular mechanism in high risk pancreatic cysts and pancreatic cancer.
A K M Firoj Mahmud, Dina Gamaleldin Mansour Aly, Yelin Zhao, Mikael Benson, Martin Smelik, Xinxiu Li

Sci Rep· January 2025

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Multiomics biomarkers were not superior to clinical variables for pan-cancer screening.
Martin Smelik, Yelin Zhao, Dina Mansour Aly, Akm Firoj Mahmud, Oleg Sysoev, Xinxiu Li

Commun Med (Lond)· November 2024

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An interactive atlas of genomic, proteomic, and metabolomic biomarkers promotes the potential of proteins to predict complex diseases.
Martin Smelik, Yelin Zhao, Xinxiu Li, Joseph Loscalzo, Oleg Sysoev

Sci Rep· June 2024

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Transcript and protein signatures derived from shared molecular interactions across cancers are associated with mortality.
Yelin Zhao, Xinxiu Li, Joseph Loscalzo, Martin Smelik, Oleg Sysoev

J Transl Med· May 2024

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Targeting LEF1-mediated epithelial-mesenchymal transition reverses lenvatinib resistance in hepatocellular carcinoma.
Xinxiu Li, Hongmeng Su, Wenqing Tang, Shihui Shu, Luyu Zhao

Invest New Drugs· April 2024

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DNA G-Quadruplex in NRP1 Promoter Facilitates SARS-CoV-2 Infection.
Pihai Gong, Rongxin Zhang, Ke Xiao, Huiling Shu, Xinxiu Li

Int J Mol Sci· April 2024

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An interactive atlas of genomic, proteomic, and metabolomic biomarkers promotes the potential of proteins to predict complex diseases.
Mikael Benson, Martin Smelik, Xinxiu Li, Joseph Loscalzo, Oleg Sysoev, Yelin Zhao

Res Sq· March 2024

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scDrugPrio: a framework for the analysis of single-cell transcriptomics to address multiple problems in precision medicine in immune-mediated inflammatory diseases.
Samuel Schäfer, Martin Smelik, Oleg Sysoev, Yelin Zhao, Desiré Eklund, Sandra Lilja, Antonio Julia, Xinxiu Li

Genome Med· March 2024

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Construction of Mn doped CuS nanozymes for synergistic tumor therapy in NIR-I/II bio-windows.
Meng Wang, Qi Huang, Ruixin Ma, Shuozhe Wang, Xinxiu Li, Qingli Huang

Colloids Surf B Biointerfaces· February 2024

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Co-overexpression of BRD4 and CDK7 promotes cell proliferation and predicts poor prognosis in HCC.
Xinxiu Li, Chuqian Zheng, Yue Liu, Hui Sun, Yanyan Qian

Heliyon· January 2024

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scDrugPrio: A framework for the analysis of single-cell transcriptomics to address multiple problems in precision medicine in immune-mediated inflammatory diseases.
Samuel Schäfer, Martin Smelik, Oleg Sysoev, Yelin Zhao, Desiré Eklund, Sandra Lilja, Antonio Julia, Xinxiu Li

bioRxiv· November 2023

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Multi-organ single-cell analysis reveals an on/off switch system with potential for personalized treatment of immunological diseases.
Sandra Lilja, Xinxiu Li, Martin Smelik, Eun Jung Lee, Joseph Loscalzo, Yelin Zhao

Cell Rep Med· March 2023

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A dynamic single cell-based framework for digital twins to prioritize disease genes and drug targets.
Xinxiu Li, Eun Jung Lee, Sandra Lilja, Joseph Loscalzo, Samuel Schäfer, Martin Smelik, Yelin Zhao

Genome Med· May 2022

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TRERNA1 upregulation mediated by HBx promotes sorafenib resistance and cell proliferation in HCC via targeting NRAS by sponging miR-22-3p.
Wei Song, Chuqian Zheng, Min Liu, Ying Xu, Yanyan Qian, Xinxiu Li, Yiping Li

Mol Ther· August 2021

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Edaravone Plays Protective Effects on LPS-Induced Microglia by Switching M1/M2 Phenotypes and Regulating NLRP3 Inflammasome Activation.
Jiping Li, Xinping Dai, Liuyi Zhou, Xinxiu Li, Dongxiao Pan

Front Pharmacol· May 2021

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Meta-Analysis of Expression Profiling Data Indicates Need for Combinatorial Biomarkers in Pediatric Ulcerative Colitis.
Xinxiu Li, Eun Jung Lee, Danuta R Gawel, Sandra Lilja, Samuel Schäfer

J Immunol Res· March 2021

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Computational fluid dynamics simulation of time-resolved blood flow in Budd-Chiari syndrome with inferior vena cava stenosis and its implication for postoperative efficacy assessment.
Yinghong Zhao, Jie Ping, Xianchao Yu, Yanfeng Cui, Jie Yin, Xinxiu Li

Clin Biomech (Bristol)· February 2021

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Corrigendum to "Bulk and single cell transcriptomic data indicate that a dichotomy between inflammatory pathways in peripheral blood and arthritic joints complicates biomarker discovery" [Cytokine 127 (2020) 154960].
Eun Jung Lee, Sandra Lilja, Xinxiu Li, Samuel Schäfer, Huan Zhang

Cytokine· September 2020

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Correction to: A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases.
Danuta R Gawel, Jordi Serra-Musach, Sandra Lilja, Jesper Aagesen, Alex Arenas, Malin Bengnér, Xinxiu Li, Oliver Seifert

Genome Med· April 2020

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Bulk and single cell transcriptomic data indicate that a dichotomy between inflammatory pathways in peripheral blood and arthritic joints complicates biomarker discovery.
Eun Jung Lee, Sandra Lilja, Xinxiu Li, Samuel Schäfer, Huan Zhang

Cytokine· March 2020

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Inhibition of CXCL1-CXCR2 axis ameliorates cisplatin-induced acute kidney injury by mediating inflammatory response.
Peng Liu, Xinxiu Li, Weixing Lv, Zhaojun Xu

Biomed Pharmacother· February 2020

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Digital twins to personalize medicine.
Bergthor Björnsson, Carl Borrebaeck, Nils Elander, Thomas Gasslander, Danuta R Gawel, Xinxiu Li, Sandra Lilja

Genome Med· December 2019

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An algorithm-based meta-analysis of genome- and proteome-wide data identifies a combination of potential plasma biomarkers for colorectal cancer.
Danuta R Gawel, Eun Jung Lee, Xinxiu Li, Sandra Lilja, Andreas Matussek, Renate Slind Olsen

Sci Rep· October 2019

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