Publications by authors named "Xiufang Pan"

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DWORF expression is reduced in a large animal model of Duchenne muscular dystrophy.
Aaron M Gibson, Xiufang Pan, Omar Brito-Estrada, James A Teixeira, Lauren K Carl

Dis Model Mech· June 2025

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Adeno-Associated Virus 8 and 9 Myofibre Type/Size Tropism Profiling Reveals Therapeutic Effect of Microdystrophin in Canines.
Matthew J Burke, Braiden M Blatt, James A Teixeira, Dennis O Pérez-López, Yongping Yue, Xiufang Pan

J Cachexia Sarcopenia Muscle· February 2025

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Genetic reduction of skeletal muscle glycogen synthase 1 abundance reveals that the refeeding-induced reversal of elevated insulin-stimulated glucose uptake after exercise is not attributable to achieving a high muscle glycogen concentration.
Seong Eun Kwak, Haiyan Wang, Xiufang Pan, Dongsheng Duan, Gregory D Cartee

FASEB J· November 2024

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Phosphorylation of AS160-serine 704 is not essential for exercise-increase in insulin-stimulated glucose uptake by skeletal muscles from female or male rats.
Haiyan Wang, Seong Eun Kwak, Amy Zheng, Edward B Arias, Xiufang Pan

Am J Physiol Endocrinol Metab· June 2024

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A novel genetic model provides a unique perspective on the relationship between postexercise glycogen concentration and increases in the abundance of key metabolic proteins after acute exercise.
Seong Eun Kwak, Amy Zheng, Edward B Arias, Haiyan Wang, Xiufang Pan

PLoS One· February 2024

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AS160 expression, but not AS160 Serine-588, Threonine-642, and Serine-704 phosphorylation, is essential for elevated insulin-stimulated glucose uptake by skeletal muscle from female rats after acute exercise.
Haiyan Wang, Amy Zheng, Edward B Arias, Seong Eun Kwak, Xiufang Pan

FASEB J· July 2023

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Dwarf Open Reading Frame (DWORF) Gene Therapy Ameliorated Duchenne Muscular Dystrophy Cardiomyopathy in Aged mdx Mice.
Emily D Morales, Yongping Yue, Thais B Watkins, Jin Han, Xiufang Pan

J Am Heart Assoc· February 2023

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Assessment of systemic AAV-microdystrophin gene therapy in the GRMD model of Duchenne muscular dystrophy.
Sharla M Birch, Michael W Lawlor, Thomas J Conlon, Lee-Jae Guo, Julie M Crudele, Xiufang Pan

Sci Transl Med· January 2023

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Microdystrophin Therapy Rescues Impaired Na Currents in Cardiac Purkinje Fibers From Dystrophin-Deficient Mdx Mice.
Janine Ebner, Xiufang Pan, Yongping Yue, Spyridon Sideromenos, Jessica Marksteiner

Circ Arrhythm Electrophysiol· August 2022

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Rational engineering of a functional CpG-free ITR for AAV gene therapy.
Xiufang Pan, Yongping Yue, Maria Boftsi, Lakmini P Wasala, Ngoc Tam Tran

Gene Ther· June 2022

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Exercise-Induced Improvement in Insulin-Stimulated Glucose Uptake by Rat Skeletal Muscle Is Absent in Male AS160-Knockout Rats, Partially Restored by Muscle Expression of Phosphomutated AS160, and Fully Restored by Muscle Expression of Wild-Type AS160.
Amy Zheng, Edward B Arias, Haiyan Wang, Seong Eun Kwak, Xiufang Pan

Diabetes· February 2022

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Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models.
Chady H Hakim, Sandeep R P Kumar, Dennis O Pérez-López, Nalinda B Wasala, Dong Zhang, Xiufang Pan

Nat Commun· November 2021

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Micro-dystrophin AAV Vectors Made by Transient Transfection and Herpesvirus System Are Equally Potent in Treating mdx Mouse Muscle Disease.
Chady H Hakim, Nathalie Clément, Lakmini P Wasala, Hsiao T Yang, Yongping Yue, Xiufang Pan

Mol Ther Methods Clin Dev· September 2020

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An Engineered Galactosylceramidase Construct Improves AAV Gene Therapy for Krabbe Disease in Twitcher Mice.
Xiufang Pan, Scott A Sands, Yongping Yue, Keqing Zhang, Steven M LeVine

Hum Gene Ther· September 2019

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AAV9 Edits Muscle Stem Cells in Normal and Dystrophic Adult Mice.
Michael E Nance, Ruicheng Shi, Chady H Hakim, Nalinda B Wasala, Yongping Yue, Xiufang Pan

Mol Ther· September 2019

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AAV CRISPR editing rescues cardiac and muscle function for 18 months in dystrophic mice.
Chady H Hakim, Nalinda B Wasala, Christopher E Nelson, Lakmini P Wasala, Yongping Yue, Xiufang Pan

JCI Insight· December 2018

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Nitric oxide-dependent attenuation of noradrenaline-induced vasoconstriction is impaired in the canine model of Duchenne muscular dystrophy.
Kasun Kodippili, Chady H Hakim, Hsiao T Yang, Xiufang Pan, N Nora Yang

J Physiol· November 2018

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Dual AAV Gene Therapy for Duchenne Muscular Dystrophy with a 7-kb Mini-Dystrophin Gene in the Canine Model.
Kasun Kodippili, Chady H Hakim, Xiufang Pan, Hsiao T Yang, Yongping Yue

Hum Gene Ther· March 2018

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A Five-Repeat Micro-Dystrophin Gene Ameliorated Dystrophic Phenotype in the Severe DBA/2J-mdx Model of Duchenne Muscular Dystrophy.
Chady H Hakim, Nalinda B Wasala, Xiufang Pan, Kasun Kodippili, Yongping Yue

Mol Ther Methods Clin Dev· September 2017

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Dystrophin contains multiple independent membrane-binding domains.
Junling Zhao, Kasun Kodippili, Yongping Yue, Chady H Hakim, Lakmini Wasala, Xiufang Pan

Hum Mol Genet· September 2016

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In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.
Christopher E Nelson, Chady H Hakim, David G Ousterout, Pratiksha I Thakore, Eirik A Moreb, Xiufang Pan

Science· January 2016

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Safe and bodywide muscle transduction in young adult Duchenne muscular dystrophy dogs with adeno-associated virus.
Yongping Yue, Xiufang Pan, Chady H Hakim, Kasun Kodippili, Keqing Zhang

Hum Mol Genet· October 2015

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AAV-8 is more efficient than AAV-9 in transducing neonatal dog heart.
Xiufang Pan, Yongping Yue, Keqing Zhang, Chady H Hakim, Kasun Kodippili

Hum Gene Ther Methods· April 2015

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Structural and temporal requirements of Wnt/PCP protein Vangl2 function for convergence and extension movements and facial branchiomotor neuron migration in zebrafish.
Xiufang Pan, Vinoth Sittaramane, Suman Gurung, Anand Chandrasekhar

Mech Dev· February 2014

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The PCP protein Vangl2 regulates migration of hindbrain motor neurons by acting in floor plate cells, and independently of cilia function.
Vinoth Sittaramane, Xiufang Pan, Derrick M Glasco, Peng Huang, Suman Gurung

Dev Biol· October 2013

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