Publications by authors named "Xu'ai Lin"

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2-Hydroxychalcone is a gonococcal-specific antimicrobial with activity against elongation factor Tu and butanediol dehydrogenase.
Jianglin Zhang, Fan Yang, Xia Sun, Lingyu Gao, Jing Yan, Xu'ai Lin

Life Sci· November 2025

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High-level ceftriaxone resistance due to transfer of penA allele 60.001 into endemic gonococcal lineages in Hangzhou, China.
Fan Yang, Xia Sun, Ying Fu, Feng Zhao, Xu'ai Lin

J Antimicrob Chemother· November 2024

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Gonococcal OMV-delivered PorB induces epithelial cell mitophagy.
Shuai Gao, Lingyu Gao, Dailin Yuan, Xu'ai Lin, Stijn van der Veen

Nat Commun· February 2024

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Th1-polarized MtrE-based gonococcal vaccines display prophylactic and therapeutic efficacy.
Shuaijie Song, Shuyi Wang, Xiaoyun Jiang, Fan Yang, Shuai Gao, Xu'ai Lin

Emerg Microbes Infect· December 2023

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Epithelial Cell NOD1/IRGM Recruits STX17 to Neisseria gonorrhoeae-Containing Endosomes to Initiate Lysosomal Degradation.
Shuai Gao, Dailin Yuan, Lingyu Gao, Fan Yang, Xu'ai Lin

J Infect Dis· December 2023

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Bacitracin enhances ceftriaxone susceptibility of the high-level ceftriaxone-resistant gonococcal FC428 clone.
Yuhua Gu, Shuaijie Song, Qingrui Zhu, Ruilin Jiao, Xu'ai Lin

Microbiol Spectr· December 2023

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Correction: Mononuclear-macrophages but not neutrophils act as major infiltrating anti-leptospiral phagocytes during leptospirosis.
Xu Chen, Shi-Jun Li, David M Ojcius, Ai-Hua Sun, Wei-Lin Hu, Xu'ai Lin

PLoS One· September 2023

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Antimicrobial Activity of Auranofin, Cannabidivarin, and Tolfenamic Acid against Multidrug-Resistant Neisseria gonorrhoeae.
Fan Yang, Jin Liu, Yuhua Gu, Ruilin Jiao, Jing Yan, Xu'ai Lin

Microbiol Spectr· December 2022

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Moenomycin is broadly active against multidrug-resistant Neisseria gonorrhoeae and clears an infection from a murine vaginal tract infection model.
Fan Yang, Shuai Gao, Jing Yan, Xu'ai Lin, Stijn van der Veen

J Antimicrob Chemother· August 2022

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Cyclic-di-GMP stimulates keratinocyte innate immune responses and attenuates methicillin-resistant Staphylococcus aureus colonization in a murine skin wound infection model.
Shuai Gao, Abidullah Khan, Xuhong Chen, Guohui Xiao, Stijn van der Veen, Xu'ai Lin

BMC Microbiol· July 2022

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Safflower injection inhibits pulmonary arterial remodeling in a monocrotaline-induced pulmonary arterial hypertension rat model.
Aifeng Chen, Shibiao Ding, Liangliang Kong, Jianpu Xu, Fei He, Xu'ai Lin

Z Naturforsch C J Biosci· January 2021

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Retraction: Endocytic recycling and vesicular transport systems mediatetranscytosis of Leptospira interrogans across cell monolayer.
Yang Li, Kai-Xuan Li, Wei-Lin Hu, David M Ojcius, Jia-Qi Fang, Xu'ai Lin

Elife· December 2020

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M16-Type Metallopeptidases Are Involved in Virulence for Invasiveness and Diffusion of Leptospira interrogans and Transmission of Leptospirosis.
Yu-Mei Ge, Ai-Hua Sun, David M Ojcius, Shi-Jun Li, Wei-Lin Hu, Xu'ai Lin

J Infect Dis· August 2020

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Characterization of CRISPR-Cas systems in Leptospira reveals potential application of CRISPR in genotyping of Leptospira interrogans.
Guohui Xiao, Yusi Yi, Rongbo Che, Qinchao Zhang, Muhammad Imran, Xu'ai Lin

APMIS· April 2019

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Endocytic recycling and vesicular transport systems mediate transcytosis of across cell monolayer.
Yang Li, Kai-Xuan Li, Wei-Lin Hu, David M Ojcius, Jia-Qi Fang, Xu'ai Lin

Elife· April 2019

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Haemolysin Sph2 of Leptospira interrogans induces cell apoptosis via intracellular reactive oxygen species elevation and mitochondrial membrane injury.
Rongbo Che, Shibiao Ding, Qinchao Zhang, Weiqun Yang, Jie Yan, Xu'ai Lin

Cell Microbiol· January 2019

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vWA proteins of Leptospira interrogans induce hemorrhage in leptospirosis by competitive inhibition of vWF/GPIb-mediated platelet aggregation.
Jia-Qi Fang, Muhammad Imran, Wei-Lin Hu, David M Ojcius, Yang Li, Xu'ai Lin

EBioMedicine· November 2018

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A novel Fas-binding outer membrane protein and lipopolysaccharide of Leptospira interrogans induce macrophage apoptosis through the Fas/FasL-caspase-8/-3 pathway.
Peng Du, Shi-Jun Li, David M Ojcius, Kai-Xuan Li, Wei-Lin Hu, Xu'ai Lin

Emerg Microbes Infect· July 2018

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Identification and Characterization of c-di-GMP Metabolic Enzymes of and c-di-GMP Fluctuations After Thermal Shift and Infection.
Guohui Xiao, Liangliang Kong, Rongbo Che, Yusi Yi, Qinchao Zhang, Xu'ai Lin

Front Microbiol· April 2018

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A leptospiral AAA+ chaperone-Ntn peptidase complex, HslUV, contributes to the intracellular survival of Leptospira interrogans in hosts and the transmission of leptospirosis.
Shi-Lei Dong, Wei-Lin Hu, Yu-Mei Ge, David M Ojcius, Xu'ai Lin

Emerg Microbes Infect· November 2017

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Mononuclear-macrophages but not neutrophils act as major infiltrating anti-leptospiral phagocytes during leptospirosis.
Xu Chen, Shi-Jun Li, David M Ojcius, Ai-Hua Sun, Wei-Lin Hu, Xu'ai Lin

PLoS One· September 2017

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Chimeric epitope vaccine against Leptospira interrogans infection and induced specific immunity in guinea pigs.
Xu'ai Lin, Guohui Xiao, Dongjiao Luo, Liangliang Kong, Xu Chen

BMC Microbiol· October 2016

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Eosinophils from Murine Lamina Propria Induce Differentiation of Naïve T Cells into Regulatory T Cells via TGF-β1 and Retinoic Acid.
Hong-Hu Chen, Ai-Hua Sun, David M Ojcius, Wei-Lin Hu, Yu-Mei Ge, Xu'ai Lin

PLoS One· June 2016

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RETRACTED: ChpK and MazF of the toxin-antitoxin modules are involved in the virulence of Leptospira interrogans during infection.
Komi Koukoura Komi, Yu-Mei Ge, Xiao-Yang Xin, David M Ojcius, Dexter Sun, Wei-Lin Hu, Xu'ai Lin

Microbes Infect· January 2015

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Leptospira and leptospirosis in China.
Weilin Hu, Xu'ai Lin, Jie Yan

Curr Opin Infect Dis· October 2014

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