Publications by authors named "Xuenan Chen"

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Uncovering potential molecular markers and pathological mechanisms of Parkinson's disease and myocardial infarction based on bioinformatics analysis.
Jian Liu, Lu Xing, Tianye Lan, Qiang Wang, Yitong Wang, Xuenan Chen

Technol Health Care· July 2025

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Ginsenoside Rc maintains sleep rhythm homeostasis by alleviating oxidative stress.
Xuenan Chen, Xiuci Yan, Chenxu Jing, Baoyu Fu, Wenqi Jin

Phytomedicine· June 2025

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GPR132 regulates the function of NK cells through the Gαs/CSK/ZAP70/NF-κB signaling pathway as a potential immune checkpoint.
Xinhui Hui, Min Xue, Yaojun Ren, Yiran Chen, Xuenan Chen

Sci Adv· March 2025

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Bile acids as a key target: traditional Chinese medicine for precision management of insulin resistance in type 2 diabetes mellitus through the gut microbiota-bile acids axis.
Yu Wang, Jing Yu, Binqin Chen, Wenqi Jin, Meili Wang, Xuenan Chen

Front Endocrinol (Lausanne)· December 2024

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Jie-Du-Tong-Luo formula protects C2C12 myotubes against high glucose and palmitic acid injury by activating the PI3K/Akt/PPARγ pathway .
Manying Wang, Xuenan Chen, Xiuci Yan, Changjiu Cai, Limei Ren

Heliyon· August 2024

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Bioactive glass 1393 promotes angiogenesis and accelerates wound healing through ROS/P53/MMP9 signaling pathway.
Xuenan Chen, Xinyu Ran, Xuebo Wei, Lifei Zhu, Shaodong Chen

Regen Ther· June 2024

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New insights into ginsenoside Rg1 regulating the niche to inhibit age-induced germline stem cells depletion through targeting ECR/BMP signaling pathway in .
Baoyu Fu, Rui Ma, Fangbing Liu, Xuenan Chen, Manying Wang

Aging (Albany NY)· February 2024

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The effect of chronic, non-pathogenic maternal immune activation on offspring postnatal muscle and immune outcomes.
Erin E Bryan, Nick M Bode, Xuenan Chen, Elli S Burris, Danielle C Johnson

J Anim Sci· January 2024

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A 4.7-kDa polysaccharide from Panax ginseng suppresses Aβ pathology via mitophagy activation in cross-species Alzheimer's disease models.
Shuai Zhang, Fangbing Liu, Jinmeng Li, Chenxu Jing, Jing Lu, Xuenan Chen

Biomed Pharmacother· November 2023

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Major ginsenosides from promote aerobic cellular respiration and SIRT1-mediated mitochondrial biosynthesis in cardiomyocytes and neurons.
Qingxia Huang, Tingting Lou, Jing Lu, Manying Wang, Xuenan Chen, Chenxu Jing

J Ginseng Res· November 2022

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Ginseng oligosaccharides protect neurons from glutamate-induced oxidative damage through the Nrf2/HO-1 signaling pathway.
Xiuci Yan, Xuenan Chen, Chunge Fu, Chenxu Jing, Daqing Zhao

Food Funct· August 2022

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Ginsenosides improve reproductive capability of aged female through mechanism dependent on ecdysteroid receptor (ECR) and steroid signaling pathway.
Baoyu Fu, Rui Ma, Fangbing Liu, Xuenan Chen, Xiaoyu Teng

Front Endocrinol (Lausanne)· August 2022

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Ginsenoside Rf inhibits human tau proteotoxicity and causes specific LncRNA, miRNA and mRNA expression changes in Caenorhabditis elegans model of tauopathy.
Shuai Zhang, Hui Wang, Jing Wang, Wenqi Jin, Xiuci Yan, Xuenan Chen

Eur J Pharmacol· May 2022

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Maternal immune activation and dietary soy isoflavone supplementation influence pig immune function but not muscle fiber formation.
Erin E Bryan, Xuenan Chen, Brooke Nicole Smith, Ryan Neil Dilger, Anna C Dilger

J Anim Sci· May 2022

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Salicylic acid in ginseng root alleviates skin hyperpigmentation disorders by inhibiting melanogenesis and melanosome transport.
Jianzeng Liu, Rui Jiang, Jingyuan Zhou, Xiaohao Xu, Zhuo Sun, Xuenan Chen

Eur J Pharmacol· November 2021

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20(S)-ginsenoside Rg3 promotes myoblast differentiation and protects against myotube atrophy via regulation of the Akt/mTOR/FoxO3 pathway.
Manying Wang, Jixiang Ren, Xuenan Chen, Jianzeng Liu, Xiaohao Xu

Biochem Pharmacol· October 2020

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Protective effects of phenolic acid extract from ginseng on vascular endothelial cell injury induced by palmitate via activation of PI3K/Akt/eNOS pathway.
Xuenan Chen, Fan Yao, Jia Song, Baoyu Fu, Guang Sun

J Food Sci· March 2020

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Mechanism Underlying -Coumaric Acid Alleviation of Lipid Accumulation in Palmitic Acid-Treated Human Hepatoma Cells.
Xiuci Yan, Xuenan Chen, Xiaohao Xu, Jianzeng Liu, Chunge Fu

J Agric Food Chem· March 2020

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Corrigendum to "Cytoprotective effect of Fufang Lurong Jiangu capsule against hydrogen peroxide-induced oxidative stress in bone marrow stromal cell-derived osteoblasts through the Nrf2/HO-1 signaling pathway" [Biomed. Pharmacother. 121 (2020) 109676].
Wenqi Jin, Xiaoqian Zhu, Fan Yao, Xiaohao Xu, Xuenan Chen

Biomed Pharmacother· February 2020

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Total Protein Facilitates Recovery from Dexamethasone-Induced Muscle Atrophy through the Activation of Glucose Consumption in C2C12 Myotubes.
Rui Jiang, Manying Wang, Lei Shi, Jingyuan Zhou, Rui Ma, Xuenan Chen

Biomed Res Int· January 2020

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Cytoprotective effect of Fufang Lurong Jiangu capsule against hydrogen peroxide-induced oxidative stress in bone marrow stromal cell-derived osteoblasts through the Nrf2/HO-1 signaling pathway.
Wenqi Jin, Xiaoqian Zhu, Fan Yao, Xiaohao Xu, Xuenan Chen

Biomed Pharmacother· January 2020

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Proteomics analyses revealed the reduction of carbon- and nitrogen-metabolism and ginsenoside biosynthesis in the red-skin disorder of Panax ginseng.
Rui Ma, Rui Jiang, Xuenan Chen, Daqing Zhao, Tong Li

Funct Plant Biol· November 2019

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Protective effect of pig brain polypeptides against corticosterone-induced oxidative stress, inflammatory response, and apoptosis in PC12 cells.
Wenqi Jin, Xiaohao Xu, Xuenan Chen, Wenxiu Qi, Jing Lu

Biomed Pharmacother· July 2019

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Active polypeptides from Hirudo inhibit endothelial cell inflammation and macrophage foam cell formation by regulating the LOX-1/LXR-α/ABCA1 pathway.
Jing Lu, Xuenan Chen, Xiaohao Xu, Jianzeng Liu, Zepeng Zhang, Hong Chen

Biomed Pharmacother· July 2019

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Ginsenoside Rb3 exerts protective properties against cigarette smoke extract-induced cell injury by inhibiting the p38 MAPK/NF-κB and TGF-β1/VEGF pathways in fibroblasts and epithelial cells.
Manying Wang, Xuenan Chen, Wenqi Jin, Xiaohao Xu, Xiangyan Li

Biomed Pharmacother· December 2018

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