Publications by authors named "Xufang Ru"

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Structure-Inspired Lineage-Specific Matrix for Endogenous Neurogenesis in Spinal Cord Injury.
Bo Wu, Xuejiao Lei, Xufang Ru, Jiangling Zhou, Hao Liu

Research (Wash D C)· August 2025

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CKN reduces TLR4-mediated inflammation and cerebral I/R injury by activating the LXRα/ABCA1 pathway in microglia.
Xuejiao Lei, Xiaodong Ran, Jiawei Wang, Lin Li, Niting Wu, Xufang Ru

Life Sci· June 2025

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Acetylation of α-tubulin restores endothelial cell injury and blood-brain barrier disruption after intracerebral hemorrhage in mice.
Xuejiao Lei, Eryi Sun, Xufang Ru, Yulian Quan, Xuezhu Chen

Exp Mol Med· May 2025

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Single-cell sequencing reveals intracranial microvasculature-derived CXCL12 promotes CD8 T-cell infiltration and blood-brain barrier dysfunction after subarachnoid hemorrhage in mice.
Yuanshu Li, Xufang Ru, Ya Xu, Peiwen Guo, Jiru Zhou

J Neuroinflammation· April 2025

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Peripheral cytokine interleukin-10 alleviates perihematomal edema after intracerebral hemorrhage via interleukin-10 receptor/JAK1/STAT3 signaling.
Yao Xu, Kaishan Wang, Yalan Dai, Wei Yang, Xufang Ru

CNS Neurosci Ther· June 2024

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Endothelial EGLN3-PKM2 signaling induces the formation of acute astrocytic barrier to alleviate immune cell infiltration after subarachnoid hemorrhage.
Mingxu Duan, Xufang Ru, Jiru Zhou, Yuanshu Li, Peiwen Guo

Fluids Barriers CNS· May 2024

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TIMP-3 Alleviates White Matter Injury After Subarachnoid Hemorrhage in Mice by Promoting Oligodendrocyte Precursor Cell Maturation.
Peiwen Guo, Xufang Ru, Jiru Zhou, Mao Chen, Yanling Li

Cell Mol Neurobiol· April 2024

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Hydrophobic Polystyrene-Modified Gelatin Enhances Fast Hemostasis and Tissue Regeneration in Traumatic Brain Injury.
Wenyan Li, Kaige Xu, Yuqing Liu, Xuejiao Lei, Xufang Ru

Adv Healthc Mater· December 2023

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Myelin sheath injury and repairment after subarachnoid hemorrhage.
Mao Chen, Peiwen Guo, Xufang Ru, Yujie Chen, Shilun Zuo

Front Pharmacol· April 2023

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NLRP3-dependent lipid droplet formation contributes to posthemorrhagic hydrocephalus by increasing the permeability of the blood-cerebrospinal fluid barrier in the choroid plexus.
Zhaoqi Zhang, Peiwen Guo, Liang Liang, Shiju Jila, Xufang Ru

Exp Mol Med· March 2023

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A redox-reactive delivery system via neural stem cell nanoencapsulation enhances white matter regeneration in intracerebral hemorrhage mice.
Xuejiao Lei, Quan Hu, Hongfei Ge, Xuyang Zhang, Xufang Ru

Bioeng Transl Med· March 2023

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EphA4/EphrinB2 signaling mediates pericyte-induced transient glia limitans formation as a secondary protective barrier after subarachnoid hemorrhage in mice.
Jiru Zhou, Peiwen Guo, Mingxu Duan, Junhan Li, Xufang Ru

Exp Neurol· February 2023

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Knockout of transient receptor potential ankyrin 1 (TRPA1) modulates the glial phenotype and alleviates perihematomal neuroinflammation after intracerebral hemorrhage in mice via MAPK/NF-κB signaling.
Min Xia, Yù-Jié Chen, Beike Chen, Xufang Ru, Jie Wang

Neuroreport· February 2023

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Discovering hematoma-stimulated circuits for secondary brain injury after intraventricular hemorrhage by spatial transcriptome analysis.
Le Zhang, Jiayidaer Badai, Guan Wang, Xufang Ru, Wenkai Song, Runsheng Chen

Front Immunol· February 2023

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Lipocalin-2-Mediated Insufficient Oligodendrocyte Progenitor Cell Remyelination for White Matter Injury After Subarachnoid Hemorrhage via SCL22A17 Receptor/Early Growth Response Protein 1 Signaling.
Qiang Li, Xufang Ru, Yang Yang, Hengli Zhao, Jie Qu, Huaizhen Ruan

Neurosci Bull· December 2022

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MiR-706 alleviates white matter injury via downregulating PKCα/MST1/NF-κB pathway after subarachnoid hemorrhage in mice.
Xufang Ru, Jie Qu, Qiang Li, Jiru Zhou, Suna Huang

Exp Neurol· July 2021

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Secondary White Matter Injury and Therapeutic Targets After Subarachnoid Hemorrhage.
Xufang Ru, Ling Gao, Jiru Zhou, Qiang Li, Shilun Zuo

Front Neurol· July 2021

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Nrf1 Is Endowed with a Dominant Tumor-Repressing Effect onto the Wnt/-Catenin-Dependent and Wnt/-Catenin-Independent Signaling Networks in the Human Liver Cancer.
Jiayu Chen, Meng Wang, Yuancai Xiang, Xufang Ru, Yonggang Ren

Oxid Med Cell Longev· November 2020

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Developing the novel bioinformatics algorithms to systematically investigate the connections among survival time, key genes and proteins for Glioblastoma multiforme.
Yujie You, Xufang Ru, Wanjing Lei, Tingting Li, Ming Xiao, Huiru Zheng

BMC Bioinformatics· September 2020

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Development of an Early Prediction Model for Subarachnoid Hemorrhage With Genetic and Signaling Pathway Analysis.
Wanjing Lei, Han Zeng, Hua Feng, Xufang Ru, Qiang Li, Huiru Zheng

Front Genet· April 2020

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Unification of Opposites between Two Antioxidant Transcription Factors Nrf1 and Nrf2 in Mediating Distinct Cellular Responses to the Endoplasmic Reticulum Stressor Tunicamycin.
Yu-Ping Zhu, Ze Zheng, Shaofan Hu, Xufang Ru, Zhuo Fan

Antioxidants (Basel)· December 2019

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Distinct isoforms of Nrf1 diversely regulate different subsets of its cognate target genes.
Meng Wang, Lu Qiu, Xufang Ru, Yijiang Song, Yiguo Zhang

Sci Rep· February 2019

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Oncogenic Activation of Nrf2, Though as a Master Antioxidant Transcription Factor, Liberated by Specific Knockout of the Full-Length Nrf1α that Acts as a Dominant Tumor Repressor.
Lu Qiu, Meng Wang, Shaofan Hu, Xufang Ru, Yonggang Ren

Cancers (Basel)· December 2018

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Nexilin Regulates Oligodendrocyte Progenitor Cell Migration and Remyelination and Is Negatively Regulated by Protease-Activated Receptor 1/Ras-Proximate-1 Signaling Following Subarachnoid Hemorrhage.
Qiang Li, Hengli Zhao, Pengyu Pan, Xufang Ru, Shilun Zuo, Huaizhen Ruan

Front Neurol· April 2018

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TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells.
Yonggang Ren, Lu Qiu, Fenglin Lü, Xufang Ru, Shaojun Li

Sci Rep· April 2016

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