Publications by authors named "Xufeng Cen"

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Preclinical safety and toxicokinetic evaluation of TJ0113, a first-in-class mitophagy inducer for Parkinson's disease.
Yanan Tian, Fengqi Wang, Jikai Shen, Ruiqi Zhang, Qianwen Chen, Xufeng Cen

Toxicol Appl Pharmacol· September 2025

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TJ0113-induced mitophagy in acute liver failure detected by Raman microspectroscopy.
Chunlian Huang, Jiaqi Liao, Xufeng Cen, Changwei Jiao, Sijia Chen

Redox Biol· June 2025

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TJ0113 attenuates fibrosis in metabolic dysfunction-associated steatohepatitis by inducing mitophagy.
Chun-Lian Huang, Shen Qi-En, Xu-Feng Cen, Ting Ye, Hang-Shuai Qu

Int Immunopharmacol· May 2025

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A deep learning framework for screening of anticancer drugs at the single-cell level.
Peijing Zhang, Xueyi Wang, Xufeng Cen, Qi Zhang, Yuting Fu

Natl Sci Rev· February 2025

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Oncogenic role of RARG rearrangements in acute myeloid leukemia resembling acute promyelocytic leukemia.
Feng Wang, Luyao Zhao, Yun Tan, Xufeng Cen, Huan Gao

Nat Commun· January 2025

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Mitophagy Regulates Kidney Diseases.
Xiaolu Fan, Linlin Wu, Fengqi Wang, Dong Liu, Xufeng Cen

Kidney Dis (Basel)· December 2024

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Mitophagy defect mediates the aging-associated hallmarks in Hutchinson-Gilford progeria syndrome.
Yingying Sun, Le Xu, Yi Li, Shunze Jia, Gang Wang, Xufeng Cen

Aging Cell· June 2024

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Hippocampal mitophagy contributes to spatial memory via maintaining neurogenesis during the development of mice.
Le Xu, Saboor Saeed, Xinxu Ma, Xufeng Cen, Yifei Sun

CNS Neurosci Ther· June 2024

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Hsc70 promotes anti-tumor immunity by targeting PD-L1 for lysosomal degradation.
Xiaoyan Xu, Tingxue Xie, Mengxin Zhou, Yaqin Sun, Fengqi Wang, Xufeng Cen

Nat Commun· May 2024

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Novel mitophagy inducer alleviates lupus nephritis by reducing myeloid cell activation and autoantigen presentation.
Huijing Wang, Mingdi Shen, Yanhong Ma, Lan Lan, Xue Jiang, Xufeng Cen

Kidney Int· April 2024

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ARIH1 activates STING-mediated T-cell activation and sensitizes tumors to immune checkpoint blockade.
Xiaolan Liu, Xufeng Cen, Ronghai Wu, Ziyan Chen, Yanqi Xie

Nat Commun· July 2023

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Spatially resolved proteomics via tissue expansion.
Lu Li, Cuiji Sun, Yaoting Sun, Zhen Dong, Runxin Wu, Xufeng Cen

Nat Commun· November 2022

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Correction to: Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model.
Xiaoyan Xu, Yaqin Sun, Xufeng Cen, Bing Shan, Qingwei Zhao

Protein Cell· March 2022

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Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model.
Xiaoyan Xu, Yaqin Sun, Xufeng Cen, Bing Shan, Qingwei Zhao

Protein Cell· October 2021

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SC75741, A Novel c-Abl Inhibitor, Promotes the Clearance of TDP25 Aggregates ATG5-Dependent Autophagy Pathway.
Dongheng Zhou, Huanhuan Yan, Shuying Yang, Yuhong Zhang, Xiaoyan Xu, Xufeng Cen

Front Pharmacol· October 2021

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Mitophagy Regulates Neurodegenerative Diseases.
Xufeng Cen, Manke Zhang, Mengxin Zhou, Lingzhi Ye, Hongguang Xia

Cells· July 2021

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ARIH1 signaling promotes anti-tumor immunity by targeting PD-L1 for proteasomal degradation.
Youqian Wu, Chao Zhang, Xiaolan Liu, Zhengfu He, Bing Shan, Xufeng Cen

Nat Commun· April 2021

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Targeting MCL1 to induce mitophagy is a potential therapeutic strategy for Alzheimer disease.
Xufeng Cen, Xiaoyan Xu, Hongguang Xia

Autophagy· March 2021

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Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimer's disease mouse model.
Xufeng Cen, Yanying Chen, Xiaoyan Xu, Ronghai Wu, Fusheng He

Nat Commun· November 2020

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Cyclic AMP Inhibits the Activity and Promotes the Acetylation of Acetyl-CoA Synthetase through Competitive Binding to the ATP/AMP Pocket.
Xiaobiao Han, Liqiang Shen, Qijun Wang, Xufeng Cen, Jin Wang

J Biol Chem· January 2017

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A systematic study of the whole genome sequence of strain 239 provides an insight into its physiological and taxonomic properties which correlate with its position in the genus.
Biao Tang, Feng Xie, Wei Zhao, Jian Wang, Shengwang Dai, Xufeng Cen

Synth Syst Biotechnol· September 2016

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sp. nov., isolated from soil.
Biao Tang, Yucong Yu, Xiaoyang Zhi, Lingling Yang, Xufeng Cen

Int J Syst Evol Microbiol· March 2016

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Molecular evidence for the coordination of nitrogen and carbon metabolisms, revealed by a study on the transcriptional regulation of the agl3EFG operon that encodes a putative carbohydrate transporter in Streptomyces coelicolor.
Xu-Feng Cen, Jing-Zhi Wang, Guo-Ping Zhao, Ying Wang, Jin Wang

Biochem Biophys Res Commun· March 2016

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Draft Genome Sequence of the Streptothricin-Producing Strain Streptomyces sp. fd2-tb.
Biao Tang, Yucong Yu, Xufeng Cen, Yongqiang Zhu, Ruixue Dai

Genome Announc· October 2015

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Characterization of a new GlnR binding box in the promoter of amtB in Streptomyces coelicolor inferred a PhoP/GlnR competitive binding mechanism for transcriptional regulation of amtB.
Ying Wang, Xu-Feng Cen, Guo-Ping Zhao, Jin Wang

J Bacteriol· October 2012

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