Publications by authors named "Xunyi Luo"

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Design and optimization of (3-aryl-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-ones as potent PLK4 inhibitors with oral antitumor efficacy.
Sze-Wan Li, Yong Liu, Peter B Sampson, Narendra Kumar Patel, Bryan T Forrest, Xunyi Luo

Bioorg Med Chem Lett· October 2016

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The discovery of Polo-like kinase 4 inhibitors: identification of (1R,2S).2-(3-((E).4-(((cis).2,6-dimethylmorpholino)methyl)styryl). 1H.indazol-6-yl)-5'-methoxyspiro[cyclopropane-1,3'-indolin]-2'-one (CFI-400945) as a potent, orally active antitumor agent.
Peter B Sampson, Yong Liu, Bryan Forrest, Graham Cumming, Sze-Wan Li, Xunyi Luo

J Med Chem· January 2015

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Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides.
Radoslaw Laufer, Grace Ng, Yong Liu, Narendra Kumar B Patel, Louise G Edwards, Xunyi Luo

Bioorg Med Chem· September 2014

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The discovery of PLK4 inhibitors: (E)-3-((1H-Indazol-6-yl)methylene)indolin-2-ones as novel antiproliferative agents.
Radoslaw Laufer, Bryan Forrest, Sze-Wan Li, Yong Liu, Peter Sampson, Xunyi Luo

J Med Chem· August 2013

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Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress.
Kathrin Zaugg, Yi Yao, Patrick T Reilly, Karuppiah Kannan, Reza Kiarash, Xunyi Luo

Genes Dev· May 2011

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Co-expression of EGFRvIII with ErbB-2 enhances tumorigenesis: EGFRvIII mediated constitutively activated and sustained signaling pathways, whereas EGF-induced a transient effect on EGFR-mediated signaling pathways.
Hong Yu, Xiaoqi Gong, Xunyi Luo, Wei Han, Ge Hong

Cancer Biol Ther· November 2008

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Gamma-synuclein is an adipocyte-neuron gene coordinately expressed with leptin and increased in human obesity.
Pieter J Oort, Trina A Knotts, Michel Grino, Nadia Naour, Jean-Phillipe Bastard, Xunyi Luo

J Nutr· May 2008

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Identification and characterization of survival-related gene, a novel cell survival gene controlling apoptosis and tumorigenesis.
Zeng-Rong Yuan, Ruoxiang Wang, Jennifer Solomon, Xunyi Luo, Hong Sun

Cancer Res· December 2005

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Suppression of EGFRvIII-mediated proliferation and tumorigenesis of breast cancer cells by ribozyme.
Xunyi Luo, Xiaoqi Gong, Careen K Tang

Int J Cancer· May 2003

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Weak platelet agonists and U46619 induce apoptosis-like events in platelets, in the absence of phosphatidylserine exposure.
Giovanni Tonon, Xunyi Luo, Nicholas J Greco, Weidong Chen, Yufang Shi

Thromb Res· September 2002

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