Publications by authors named "Yaakov A Levine"

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Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis.
Frieda A Koopman, Sangeeta S Chavan, Sanda Miljko, Simeon Grazio, Sekib Sokolovic, P Richard Schuurman, Ashesh D Mehta, Yaakov A Levine, Michael Faltys, Ralph Zitnik

Proc Natl Acad Sci U S A· July 2016

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Neuroimmune Modulation for Drug-Refractory Rheumatoid Arthritis: Long-Term Safety and Efficacy in Patients Enrolled in a Pilot Vagus Nerve Stimulation Study.
Norman B Gaylis, David Sikes, Alan Kivitz, Diane Lewis Horowitz, Melissa Evangelista, Yaakov A Levine

Rheumatol Ther· December 2025

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Vagus nerve-mediated neuroimmune modulation for rheumatoid arthritis: a pivotal randomized controlled trial.
John R P Tesser, Angela R Crowley, Emily Jane Box, Joshua P June, Pendleton Brewster Wickersham, Yaakov A Levine

Nat Med· December 2025

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Electrical stimulation of the vagus nerve ameliorates inflammation and disease activity in a rat EAE model of multiple sclerosis.
Chandramohan Natarajan, Linh H D Le, Manojkumar Gunasekaran, Kevin J Tracey, David Chernoff, Yaakov A Levine

Proc Natl Acad Sci U S A· July 2024

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Neuroimmune Modulation Through Vagus Nerve Stimulation Reduces Inflammatory Activity in Crohn's Disease Patients: A Prospective Open-label Study.
Geert D'Haens, Michael Eberhardson, Zeljko Cabrijan, Silvio Danese, Remco van den Berg, Yaakov A Levine

J Crohns Colitis· December 2023

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Vagus Nerve Stimulation Reduces Indomethacin-Induced Small Bowel Inflammation.
April S Caravaca, Yaakov A Levine, Anna Drake, Michael Eberhardson, Peder S Olofsson

Front Neurosci· January 2022

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The brain-gut axis, inflammatory bowel disease and bioelectronic medicine.
Michael Eberhardson, Yaakov A Levine, Laura Tarnawski, Peder S Olofsson

Int Immunol· June 2021

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Vagus nerve stimulation in rheumatoid arthritis - Authors' reply.
Mark C Genovese, Yaakov A Levine, David Chernoff

Lancet Rheumatol· January 2021

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Identification of a brainstem locus that inhibits tumor necrosis factor.
Adam M Kressel, Tea Tsaava, Yaakov A Levine, Eric H Chang, Meghan E Addorisio

Proc Natl Acad Sci U S A· November 2020

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Safety and efficacy of neurostimulation with a miniaturised vagus nerve stimulation device in patients with multidrug-refractory rheumatoid arthritis: a two-stage multicentre, randomised pilot study.
Mark C Genovese, Norman B Gaylis, David Sikes, Alan Kivitz, Diane Lewis Horowitz, Yaakov A Levine

Lancet Rheumatol· September 2020

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Harnessing the Inflammatory Reflex for the Treatment of Inflammation-Mediated Diseases.
Yaakov A Levine, Michael Faltys, David Chernoff

Cold Spring Harb Perspect Med· January 2020

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Constitutive Vagus Nerve Activation Modulates Immune Suppression in Sepsis Survivors.
Minakshi Rana, Yurong Fei-Bloom, Myoungsun Son, Andrea La Bella, Mahendar Ochani, Yaakov A Levine

Front Immunol· September 2019

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Adenylyl Cyclase 6 Mediates Inhibition of TNF in the Inflammatory Reflex.
Laura Tarnawski, Colin Reardon, April S Caravaca, Mauricio Rosas-Ballina, Michael W Tusche, Yaakov A Levine

Front Immunol· September 2019

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Vagus Nerve Stimulation in Rodent Models: An Overview of Technical Considerations.
Crystal M Noller, Yaakov A Levine, Timur M Urakov, Joshua P Aronson, Mark S Nash

Front Neurosci· September 2019

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An Effective Method for Acute Vagus Nerve Stimulation in Experimental Inflammation.
April S Caravaca, Alessandro L Gallina, Laura Tarnawski, Kevin J Tracey, Valentin A Pavlov, Yaakov A Levine

Front Neurosci· August 2019

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Towards improved control of inflammatory bowel disease.
Michael Eberhardson, Charlotte R H Hedin, Marie Carlson, Laura Tarnawski, Yaakov A Levine

Scand J Immunol· March 2019

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Identification of CD163 as an antiinflammatory receptor for HMGB1-haptoglobin complexes.
Huan Yang, Haichao Wang, Yaakov A Levine, Manoj K Gunasekaran, Yongjun Wang

JCI Insight· December 2018

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Identification of CD163 as an antiinflammatory receptor for HMGB1-haptoglobin complexes.
Huan Yang, Haichao Wang, Yaakov A Levine, Manoj K Gunasekaran, Yongjun Wang

JCI Insight· December 2018

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Neurophysiologic and Chronic Safety Testing of a Miniaturized Active Implanted Device with Integrated Electrodes for Bioelectronic Medicine Applications.
Yaakov A Levine, Jesse Simon, Michael Faltys

Annu Int Conf IEEE Eng Med Biol Soc· July 2018

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Neuronal Circuits Modulate Antigen Flow Through Lymph Nodes.
William M Hanes, Peder S Olofsson, Sébastien Talbot, Tea Tsaava, Mahendar Ochani, Yaakov A Levine

Bioelectron Med· December 2016

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Emetine Di-HCl Attenuates Type 1 Diabetes Mellitus in Mice.
LaQueta K Hudson, Meghan E Dancho, Jianhua Li, Johanna B Bruchfeld, Ahmed A Ragab, Yaakov A Levine

Mol Med· October 2016

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Identification of CD163 as an antiinflammatory receptor for HMGB1-haptoglobin complexes.
Huan Yang, Haichao Wang, Yaakov A Levine, Manoj K Gunasekaran, Yongjun Wang

JCI Insight· May 2016

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Neurostimulation of the cholinergic anti-inflammatory pathway ameliorates disease in rat collagen-induced arthritis.
Yaakov A Levine, Frieda A Koopman, Michael Faltys, April Caravaca, Alison Bendele

PLoS One· April 2015

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Sequestering HMGB1 via DNA-conjugated beads ameliorates murine colitis.
Zhongliang Ju, Sangeeta S Chavan, Daniel J Antoine, Meghan Dancho, Teá Tsaava, Yaakov A Levine

PLoS One· April 2015

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α7 nicotinic acetylcholine receptor signaling inhibits inflammasome activation by preventing mitochondrial DNA release.
Ben Lu, Kevin Kwan, Yaakov A Levine, Peder S Olofsson, Huan Yang

Mol Med· August 2014

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