Publications by authors named "Yakov Pechersky"

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Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia.
Andreas Varkaris, Ermira Pazolli, Hakan Gunaydin, Qi Wang, Levi Pierce, Yakov Pechersky

Cancer Discov· February 2024

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Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
James Chen, Qi Wang, Brandon Malone, Eliza Llewellyn, Yakov Pechersky

Nat Struct Mol Biol· March 2022

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Structural mechanism for Bruton's tyrosine kinase activation at the cell membrane.
Qi Wang, Yakov Pechersky, Shiori Sagawa, Albert C Pan, David E Shaw

Proc Natl Acad Sci U S A· May 2019

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The Cremeomycin Biosynthetic Gene Cluster Encodes a Pathway for Diazo Formation.
Abraham J Waldman, Yakov Pechersky, Peng Wang, Jennifer X Wang, Emily P Balskus

Chembiochem· October 2015

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