Publications by authors named "Yamila Verdecia-Reyes"

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Synergistic anti-hypernociceptive interaction between morphine and JM-20 in neuropathic rats. Mechanistic insights into metabolism, transport, and safety.
Bárbara B Garrido-Suárez, Gabino Garrido, Addis Bellma-Menéndez, Idania Rodeiro-Guerra, Laia Tolosa, Yamila Verdecia-Reyes

Chem Biol Interact· September 2025

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A multi-target ligand (JM-20) prevents morphine-induced hyperalgesia in naïve and neuropathic rats.
Bárbara B Garrido-Suárez, Gabino Garrido, Addis Bellma-Menéndez, Guillermo Aparicio-López, Odalys Valdés-Martínez, Yamila Verdecia-Reyes

Eur J Pharmacol· November 2024

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Novel arylidene malonate derivative, KM-34, showed neuroprotective effects on in vitro and in vivo models of ischemia/reperfusion.
Jeney Ramírez-Sánchez, Maylin Wong-Guerra, Luis Arturo Fonseca-Fonseca, Elisa Nicoloso Simões-Pires, Laura García-Pupo, Yamila Verdecia-Reyes

Eur J Pharmacol· May 2021

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JM-20 protects against 6-hydroxydopamine-induced neurotoxicity in models of Parkinson's disease: Mitochondrial protection and antioxidant properties.
Luis Arturo Fonseca-Fonseca, Víctor Diogenes Amaral da Silva, Maylin Wong-Guerra, Jeney Ramírez-Sánchez, Alejandro Saúl Padrón Yaquis, Yamila Verdecia-Reyes

Neurotoxicology· January 2021

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Anti-hypernociceptive and anti-inflammatory effects of JM-20: A novel hybrid neuroprotective compound.
Bárbara B Garrido-Suárez, Gabino Garrido, Marian Castro-Labrada, Nelson Merino, Odalys Valdés, Yamila Verdecia-Reyes

Brain Res Bull· December 2020

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KM-34, a Novel Antioxidant Compound, Protects against 6-Hydroxydopamine-Induced Mitochondrial Damage and Neurotoxicity.
Luis Arturo Fonseca-Fonseca, Yanier Nuñez-Figueredo, Jeney Ramírez Sánchez, Maylin Wong Guerra, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes

Neurotox Res· August 2019

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JM-20 Treatment After MCAO Reduced Astrocyte Reactivity and Neuronal Death on Peri-infarct Regions of the Rat Brain.
Jeney Ramírez-Sánchez, Elisa Nicoloso Simões Pires, André Meneghetti, Gisele Hansel, Yanier Nuñez-Figueredo, Yamila Verdecia-Reyes

Mol Neurobiol· January 2019

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Multi-targeting effects of a new synthetic molecule (JM-20) in experimental models of cerebral ischemia.
Yanier Nuñez-Figueredo, Jeney Ramírez-Sánchez, Gilberto L Pardo Andreu, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes

Pharmacol Rep· August 2018

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Antioxidant and Neuroprotective Effects of KM-34, A Novel Synthetic Catechol, Against Oxidative Stress-Induced Neurotoxicity.
Yanier Nuñez-Figueredo, Jeney Ramirez-Sanchez, Yeniceis Alcantara Issac, Estael Ochoa-Rodriguez, Yamila Verdecia-Reyes

Drug Res (Stuttg)· May 2018

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Anti-cancer activity of a new dihydropyridine derivative, VdiE-2N, in head and neck squamous cell carcinoma.
Renata Nishida Goto, Lays Martin Sobral, Lucas Oliveira Sousa, Cristiana Bernadelli Garcia, Norberto Peporine Lopes, Yamila Verdecia-Reyes

Eur J Pharmacol· January 2018

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The cytotoxic effects of VE-3N, a novel 1,4-dihydropyridine derivative, involve the mitochondrial bioenergetic disruption via uncoupling mechanisms.
Javier Marín-Prida, Gilberto L Pardo Andreu, Camila Pederiva Rossignoli, Michael González Durruthy, Estael Ochoa Rodríguez

Toxicol In Vitro· August 2017

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Neuroprotection by JM-20 against oxygen-glucose deprivation in rat hippocampal slices: Involvement of the Akt/GSK-3β pathway.
Jeney Ramírez-Sánchez, Elisa Nicoloso Simões Pires, Yanier Nuñez-Figueredo, Gilberto L Pardo-Andreu, Luis Arturo Fonseca-Fonseca, Yamila Verdecia-Reyes

Neurochem Int· November 2015

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The effects of JM-20 on the glutamatergic system in synaptic vesicles, synaptosomes and neural cells cultured from rat brain.
Yanier Nuñez-Figueredo, Gilberto L Pardo Andreu, Samanta Oliveira Loureiro, Marcelo Ganzella, Jeney Ramírez-Sánchez, Yamila Verdecia-Reyes

Neurochem Int· February 2015

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A novel multi-target ligand (JM-20) protects mitochondrial integrity, inhibits brain excitatory amino acid release and reduces cerebral ischemia injury in vitro and in vivo.
Yanier Nuñez-Figueredo, Jeney Ramírez-Sánchez, Gisele Hansel, Elisa Nicoloso Simões Pires, Nelson Merino, Yamila Verdecia-Reyes

Neuropharmacology· October 2014

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Antioxidant effects of JM-20 on rat brain mitochondria and synaptosomes: mitoprotection against Ca²⁺-induced mitochondrial impairment.
Yanier Nuñez-Figueredo, Gilberto L Pardo-Andreu, Jeney Ramírez-Sánchez, René Delgado-Hernández, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes

Brain Res Bull· October 2014

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JM-20, a novel benzodiazepine–dihydropyridine hybrid molecule, protects mitochondria and prevents ischemic insult-mediated neural cell death in vitro.
Yanier Nuñez-Figueredo, Jeney Ramírez-Sánchez, René Delgado-Hernández, Marlene Porto-Verdecia, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes

Eur J Pharmacol· March 2014

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Characterization of the anxiolytic and sedative profile of JM-20: a novel benzodiazepine-dihydropyridine hybrid molecule.
Yanier Nuñez Figueredo, Estael Ochoa Rodríguez, Yamila Verdecia Reyes, Carmen Carrillo Domínguez, Alicia Lagarto Parra

Neurol Res· October 2013

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