Publications by authors named "Yanay Ofran"

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"Redirecting an anti-IL-1β antibody to bind a new, unrelated and computationally predicted epitope on hIL-17A".
Sharon Fischman, Itay Levin, Jean-Michel Rondeau, Marek Štrajbl, Sylvie Lehmann, Yanay Ofran

Commun Biol· September 2023

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Accurate profiling of full-length Fv in highly homologous antibody libraries using UMI tagged short reads.
Itay Levin, Marek Štrajbl, Yair Fastman, Dror Baran, Shir Twito, Yanay Ofran

Nucleic Acids Res· June 2023

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DistilProtBert: a distilled protein language model used to distinguish between real proteins and their randomly shuffled counterparts.
Yaron Geffen, Yanay Ofran, Ron Unger

Bioinformatics· September 2022

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Targeting the actin nucleation promoting factor WASp provides a therapeutic approach for hematopoietic malignancies.
Guy Biber, Aviad Ben-Shmuel, Elad Noy, Noah Joseph, Abhishek Puthenveetil, Yanay Ofran

Nat Commun· September 2021

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Computational Design of Epitope-Specific Functional Antibodies.
Guy Nimrod, Sharon Fischman, Mark Austin, Asael Herman, Feenagh Keyes, Yanay Ofran

Cell Rep· November 2018

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Computational design of antibodies.
Sharon Fischman, Yanay Ofran

Curr Opin Struct Biol· August 2018

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Integrating genomic data from high-throughput studies with computational modeling reveals differences in the molecular basis of hyposalivation between type 1 and type 2 diabetes.
Nili Tickotsky, Yanay Ofran

Clin Oral Investig· January 2018

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A novel Fer/FerT targeting compound selectively evokes metabolic stress and necrotic death in malignant cells.
Yoav Elkis, Moshe Cohen, Etai Yaffe, Shirly Satmary-Tusk, Tal Feldman, Yanay Ofran

Nat Commun· October 2017

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Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges.
Roxana Daneshjou, Yanran Wang, Yana Bromberg, Samuele Bovo, Pier L Martelli, Yanay Ofran

Hum Mutat· September 2017

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Understanding differences between synthetic and natural antibodies can help improve antibody engineering.
Anat Burkovitz, Yanay Ofran

MAbs· December 2016

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De-novo protein function prediction using DNA binding and RNA binding proteins as a test case.
Sapir Peled, Olga Leiderman, Rotem Charar, Gilat Efroni, Yaron Shav-Tal, Yanay Ofran

Nat Commun· November 2016

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How far from the SNP may the causative genes be?
Aharon Brodie, Johnathan Roy Azaria, Yanay Ofran

Nucleic Acids Res· July 2016

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PEASE: predicting B-cell epitopes utilizing antibody sequence.
Inbal Sela-Culang, Shaul Ashkenazi, Bjoern Peters, Yanay Ofran

Bioinformatics· April 2015

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Antibody specific epitope prediction-emergence of a new paradigm.
Inbal Sela-Culang, Yanay Ofran, Bjoern Peters

Curr Opin Virol· April 2015

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Large scale analysis of phenotype-pathway relationships based on GWAS results.
Aharon Brodie, Oholi Tovia-Brodie, Yanay Ofran

PLoS One· March 2015

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Potent neutralization of vaccinia virus by divergent murine antibodies targeting a common site of vulnerability in L1 protein.
Thomas Kaever, Xiangzhi Meng, Michael H Matho, Andrew Schlossman, Sheng Li, Yanay Ofran

J Virol· October 2014

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Co-expression and co-localization of hub proteins and their partners are encoded in protein sequence.
Ariel Feiglin, Shaul Ashkenazi, Avner Schlessinger, Burkhard Rost, Yanay Ofran

Mol Biosyst· April 2014

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Using a combined computational-experimental approach to predict antibody-specific B cell epitopes.
Inbal Sela-Culang, Mohammed Rafii-El-Idrissi Benhnia, Michael H Matho, Thomas Kaever, Matt Maybeno, Yanay Ofran

Structure· April 2014

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Large-scale analysis of somatic hypermutations in antibodies reveals which structural regions, positions and amino acids are modified to improve affinity.
Anat Burkovitz, Inbal Sela-Culang, Yanay Ofran

FEBS J· January 2014

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The indistinguishability of epitopes from protein surface is explained by the distinct binding preferences of each of the six antigen-binding loops.
Vered Kunik, Yanay Ofran

Protein Eng Des Sel· October 2013

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The structural basis of antibody-antigen recognition.
Inbal Sela-Culang, Vered Kunik, Yanay Ofran

Front Immunol· October 2013

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Computational identification of antigen-binding antibody fragments.
Anat Burkovitz, Olga Leiderman, Inbal Sela-Culang, Gerardo Byk, Yanay Ofran

J Immunol· March 2013

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Non-local residue-residue contacts in proteins are more conserved than local ones.
Orly Noivirt-Brik, Gershon Hazan, Ron Unger, Yanay Ofran

Bioinformatics· February 2013

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Assessing the relationship between conservation of function and conservation of sequence using photosynthetic proteins.
Shaul Ashkenazi, Rotem Snir, Yanay Ofran

Bioinformatics· December 2012

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A systematic comparison of free and bound antibodies reveals binding-related conformational changes.
Inbal Sela-Culang, Shahar Alon, Yanay Ofran

J Immunol· November 2012

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