Publications by authors named "Yanou Yang"

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Epigallocatechin-3-gallate supplementation regulates glucose redistribution through its potential endogenous receptor in grass carp ().
Fan Chen, Yunfeng Li, Xiaoyu Wang, Qianqian Gao, Yuanqi Guo, Yanou Yang

Anim Nutr· December 2025

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Effects of Renal and Hepatic Impairment on the Pharmacokinetics of Zilurgisertib.
Yan-Ou Yang, Yunlan Fang, Phillip Wang, Xiang Liu, Jay Getsy

Br J Clin Pharmacol· December 2025

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Axatilimab Immunogenicity and Clinical Relevance in Patients with Chronic Graft-Versus-Host Disease.
Yan-Ou Yang, Xing Liu, Breann Barker, Xuecheng Zhang, Peter Ordentlich

Clin Pharmacol Ther· December 2025

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Dietary Green Tea Enhances the Growth, Antioxidant Capacity, and Abundance of Beneficial Intestinal Flora of Grass Carp ().
Yuyan Li, Ruiyi Yang, Shaoyu Zhu, Cong Wang, Rui Wang, Yanou Yang

Animals (Basel)· December 2025

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Exposure-Response Relationships for Axatilimab in Patients with Chronic Graft-Versus-Host Disease.
Yan-Ou Yang, Alina Volkova, Victor Sokolov, Xing Liu, Cristina Leon

Clin Pharmacol Ther· October 2025

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Evaluation of clinical cardiac safety of zilurgisertib, an activin receptor-like kinase-2 (ALK2) inhibitor, in healthy participants.
Yan-Ou Yang, Hong Yang, Xing Liu, Xiaohua Gong, Jay Getsy

Clin Pharmacol Drug Dev· October 2025

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Effect of Itraconazole or Rifampin on Zilurgisertib Pharmacokinetics When Administered Orally in Healthy Participants.
Yan-Ou Yang, Xiaohua Gong, Phillip Wang, Xiang Liu, Jay Getsy

Clin Pharmacol Drug Dev· August 2025

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Discovery of liver-selective glucokinase activators comprising N-(4-alkylthiazol-2-yl)benzamides and N-(3-alkyl-1,2,4-thiadiazol-5-yl)benzamides for the treatment of metabolic disorders.
David S Yoon, Shung Wu, Sean S Chen, Rebecca A Smirk, Robert P Brigance, Yanou Yang

Bioorg Med Chem Lett· July 2025

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Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Axatilimab in Healthy Japanese Male Participants: Results from a Phase 1, Randomized, Double-Blind, Dose-Escalation Study.
Miwa Haranaka, Kenzo Kinami, Yan-Ou Yang, Hongfei Li, Michael Pratta

Clin Drug Investig· June 2025

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Semimechanistic Population PK/PD Modeling of Axatilimab in Healthy Participants and Patients With Solid Tumors or Chronic Graft-Versus-Host Disease.
Yan-Ou Yang, Victor Sokolov, Alina Volkova, Xing Liu, Cristina Leon

Clin Pharmacol Ther· March 2025

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Pharmacokinetics of Zilurgisertib With and Without Food from Single and Multiple Ascending Dose Phase 1 Studies in Healthy Adults.
Yan-Ou Yang, Xiaohua Gong, Jay Getsy, Phillip Wang, Xiang Liu

Eur J Drug Metab Pharmacokinet· January 2025

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Selective targeting of mutated calreticulin by the monoclonal antibody INCA033989 inhibits oncogenic function of MPN.
Edimara S Reis, Rebecca Buonpane, Hamza Celik, Caroline Marty, Angela Lei, Yan-Ou Yang

Blood· November 2024

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Discovery of 5,7-Dihydro-6-pyrrolo[2,3-]pyrimidin-6-ones as Highly Selective CDK2 Inhibitors.
Alexander Sokolsky, Sarah Winterton, Keith Kennedy, Katherine Drake, Kristine Stump, Yan-Ou Yang

ACS Med Chem Lett· November 2022

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Discovery of Novel Pyrazolopyrimidines as Potent, Selective, and Orally Bioavailable Inhibitors of ALK2.
Minh H Nguyen, Onur Atasoylu, Liangxing Wu, Kanishk Kapilashrami, Michelle Pusey, Yan-Ou Yang

ACS Med Chem Lett· July 2022

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Characterization of INCB086550: A Potent and Novel Small-Molecule PD-L1 Inhibitor.
Holly K Koblish, Liangxing Wu, Liang-Chuan S Wang, Phillip C C Liu, Richard Wynn, Yan-Ou Yang, Gengjie Yang

Cancer Discov· June 2022

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Discovery of a Partial Glucokinase Activator Clinical Candidate: Diethyl ((3-(3-((5-(Azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-isopropoxybenzamido)-1-pyrazol-1-yl)methyl)phosphonate (BMS-820132).
Yan Shi, Ying Wang, Wei Meng, Robert P Brigance, Denis E Ryono, Yanou Yang

J Med Chem· March 2022

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Discovery of an Oxycyclohexyl Acid Lysophosphatidic Acid Receptor 1 (LPA) Antagonist BMS-986278 for the Treatment of Pulmonary Fibrotic Diseases.
Peter T W Cheng, Robert F Kaltenbach, Hao Zhang, Jun Shi, Shiwei Tao, Yanou Yang

J Med Chem· November 2021

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Itacitinib (INCB039110), a JAK1 Inhibitor, Reduces Cytokines Associated with Cytokine Release Syndrome Induced by CAR T-cell Therapy.
Eduardo Huarte, Roddy S O'Connor, Michael T Peel, Selene Nunez-Cruz, John Leferovich, Yan-Ou Yang

Clin Cancer Res· December 2020

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Discovery of Potent Protease-Activated Receptor 4 Antagonists with in Vivo Antithrombotic Efficacy.
Michael M Miller, Jacques Banville, Todd J Friends, Mark Gagnon, Jon J Hangeland, Yanou Yang, Jing Yang

J Med Chem· August 2019

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Dietary conjugated linoleic acid modulates morphology, selective immune parameters, and gene expressions in the intestine of grass carp.
Long Kong, Shi-Yan Cheng, Xiao-Jun Xiang, Wen-Shu Liu, Deng-Hang Yu, Yan-Ou Yang

Fish Shellfish Immunol· March 2019

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Label-Free Bottom-Up Proteomic Workflow for Simultaneously Assessing the Target Specificity of Covalent Drug Candidates and Their Off-Target Reactivity to Selected Proteins.
Yanou Yang, Yue-Zhong Shu, W Griffith Humphreys

Chem Res Toxicol· January 2016

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Effects of dietary yeast nucleotides on growth, non-specific immunity, intestine growth and intestinal microbiota of juvenile hybrid tilapia ♀ × ♂.
Li Xu, Chao Ran, Suxu He, Jianli Zhang, Jun Hu, Yalin Yang, Yanou Yang

Anim Nutr· September 2015

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Conjugated linoleic acid alters growth performance, tissue lipid deposition, and fatty acid composition of darkbarbel catfish (Pelteobagrus vachelli).
Gui-Fang Dong, Wen-Zuo Liu, Lin-Zhou Wu, Deng-Hang Yu, Feng Huang, Yan-Ou Yang

Fish Physiol Biochem· February 2015

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Identification of human liver microsomal proteins adducted by a reactive metabolite using shotgun proteomics.
Yanou Yang, Qing Xiao, W Griffith Humphreys, Ashok Dongre, Yue-Zhong Shu

Chem Res Toxicol· September 2014

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Effects of dietary microencapsulated sodium butyrate on growth, intestinal mucosal morphology, immune response and adhesive bacteria in juvenile common carp (Cyprinus carpio) pre-fed with or without oxidised oil.
Wenshu Liu, Yanou Yang, Jianli Zhang, Delbert M Gatlin, Einar Ringø

Br J Nutr· July 2014

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