Publications by authors named "Yaya Fan"

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Intestinal mucosal barrier repair and immune regulation with an AI-developed gut-restricted PHD inhibitor.
Yanyun Fu, Xiao Ding, Man Zhang, Chunlei Feng, Ziqi Yan, Yaya Fan

Nat Biotechnol· November 2025

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Discovery and Biological Evaluation of Novel, Potent, and Orally Available CBLB Inhibitors.
Fanye Meng, Zhongying Cao, Jinxin Liu, Yazhou Wang, Zhilin Ning, Yaya Fan

J Med Chem· November 2025

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Discovery of a bifunctional PKMYT1-targeting PROTAC empowered by AI-generation.
Yazhou Wang, Xiaomin Wang, Tingting Liu, Chao Wang, Qingshuo Meng, Fanye Meng, Yaya Fan

Nat Commun· November 2025

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Covalent protein modification by multiple reactive dialdehyde metabolites of catalpol via intestinal bioactivation.
Qiuyi Jing, Hong Pan, Xiaoli Li, Yaya Fan, Jingshan Shi, Chao Fang

J Pharm Biomed Anal· August 2025

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A novel, covalent broad-spectrum inhibitor targeting human coronavirus M.
Jing Sun, Deheng Sun, Qi Yang, Dong Wang, Jingjing Peng, Yaya Fan

Nat Commun· May 2025

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Two-step metabolic activation to ortho-benzoquinone intermediate and its role in 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside-induced liver injury in mice.
Hong Pan, Guohong Zhai, Qiuyi Jing, Yaya Fan, Chao Fang

Drug Metab Dispos· March 2025

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Discovery of Bis-imidazolecarboxamide Derivatives as Novel, Potent, and Selective TNIK Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis.
Vladimir Aladinskiy, Chris Kruse, Luoheng Qin, Eugene Babin, Yaya Fan

J Med Chem· November 2024

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Covalent Binding of Reactive Anhydride of Cantharidin to Biological Amines.
Yaya Fan, Lin Chen, Qiuyi Jing, Xiaoli Li, Hong Pan, Chao Fang

Drug Metab Dispos· July 2024

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Discovery of novel MAT2A inhibitors by an allosteric site-compatible fragment growing approach.
Feng Gao, Xiaoyu Ding, Zhongying Cao, Wei Zhu, Yaya Fan

Bioorg Med Chem· February 2024

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GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis.
Jonathan M Goodwin, Ward G Walkup, Kirsty Hooper, Taoyingnan Li, Chieko Kishi-Itakura, Yaya Fan

Sci Adv· October 2021

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A Genetic Network for Systemic RNA Silencing in Plants.
Weiwei Chen, Xian Zhang, Yaya Fan, Bin Li, Eugene Ryabov

Plant Physiol· April 2018

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Roles of Dicer-Like Proteins 2 and 4 in Intra- and Intercellular Antiviral Silencing.
Cheng Qin, Bin Li, Yaya Fan, Xian Zhang, Zhiming Yu

Plant Physiol· June 2017

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The response of growth and patulin production of postharvest pathogen Penicillium expansum to exogenous potassium phosphite treatment.
Tongfei Lai, Ying Wang, Yaya Fan, Yingying Zhou, Ying Bao

Int J Food Microbiol· March 2017

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Combination treatment with Rhizoma Paridis and Rhizoma Curcuma longa extracts and 10-hydroxycamptothecin enhances the antitumor effect in H22 tumor model by increasing the plasma concentration.
Zhen Liu, Hongfa Li, Yaya Fan, Yuanxue Liu, Shuli Man

Biomed Pharmacother· October 2016

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Antioxidant and Antitumor Activities of the Extracts from Chinese Yam (Dioscorea opposite Thunb.) Flesh and Peel and the Effective Compounds.
Yuanxue Liu, Hongfa Li, Yaya Fan, Shuli Man, Zhen Liu

J Food Sci· June 2016

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Analysis of bioactive components and pharmacokinetic study of herb-herb interactions in the traditional Chinese patent medicine Tongmai Yangxin Pill.
Yaya Fan, Shuli Man, Hongfa Li, Yuanxue Liu, Zhen Liu

J Pharm Biomed Anal· February 2016

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[Graded ethanol precipitation method on physicochemical properties and antioxidant activities of polysaccharides extracted from Astragalus Radix].
Hong-fa Li, Song-bo Guo, Shu-li Man, Ya-ya Fan, Ting-ting Wang

Zhongguo Zhong Yao Za Zhi· June 2015

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