Publications by authors named "Yeka Adoke"

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Efficacies of artemether-lumefantrine, artesunate-amodiaquine, dihydroartemisinin-piperaquine, and artesunate-pyronaridine for the treatment of uncomplicated Plasmodium falciparum malaria in children aged 6 months to 10 years in Uganda: a randomised, open-label, phase 4 clinical trial.
Moses R Kamya, Joaniter I Nankabirwa, Chris Ebong, Victor Asua, Moses Kiggundu, Adoke Yeka

Lancet Infect Dis· January 2026

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Knowledge, attitudes, practices and determinants of mosquito repellent use for malaria prevention in Nangabo Ward, Wakiso District, Uganda.
Grace Kemigisha, David Musoke, Abel W Walekhwa, Adoke Yeka

Malar J· November 2025

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A novel locus associated with decreased susceptibility of Plasmodium falciparum to lumefantrine and dihydroartemisinin has emerged and spread in Uganda.
Karamoko Niare, Bersabeh Tafesse, Mayland Treat, Jacob Sadler, Martin Okitwi, Adoke Yeka

bioRxiv· August 2025

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Effectiveness of sulfadoxine-pyrimethamine plus amodiaquine and dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in Uganda: a three-arm, open-label, non-inferiority and superiority, cluster-randomised, controlled trial.
Anthony Nuwa, Kevin Baker, Richard Kajubi, Chukwudi A Nnaji, Katherine Theiss-Nyland, Adoke Yeka

Lancet Infect Dis· July 2025

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Signatures of selection and mechanisms of insecticide resistance in Ugandan : Insights from embedding translational genomics into the LLINEUP cluster randomised trial.
Lilian Namuli-Kayondo, Sanjay C Nagi, Harun Njoroge Nganga, Anastasia Hernandez-Koutoucheva, Daniel P McDermott, Adoke Yeka

bioRxiv· June 2025

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Targeting mucosal immunity in malaria control: the underexplored role of IgA.
Haruna Muwonge, Isaac Ssewanyana, Adoke Yeka, Pauline Byakika-Kibwika

Front Malar· June 2025

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Impact of indoor residual spraying on malaria incidence in Ugandan prisons: an interrupted time series analysis.
Joseph Byaruhanga, James Kisambu, Adoke Yeka, Arthur Bagonza

Malar J· May 2025

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Enhancing malaria elimination in high-transmission settings: the synergy of concurrent vector control and chemotherapy.
Ronald Mulebeke, Adoke Yeka, Jean-Pierre van Geertruyden

Malar J· April 2025

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Pharmacokinetics of Ganaplacide and Lumefantrine in Adults, Adolescents, and Children with Plasmodium falciparum Malaria Treated with Ganaplacide Plus Lumefantrine Solid Dispersion Formulation: Analysis of Data from a Multinational Phase 2 Study.
Ramachandra Sangana, Bernhards Ogutu, Adoke Yeka, Sylvia Kusemererwa, Halidou Tinto

J Clin Pharmacol· February 2025

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Artemisinin-resistant malaria in Africa demands urgent action.
Mehul Dhorda, Akira Kaneko, Ryuichi Komatsu, Achyut Kc, Salum Mshamu, Yeka Adoke

Science· July 2024

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LLIN Evaluation in Uganda Project (LLINEUP)-effects of a vector control trial on Plasmodium infection prevalence and genotypic markers of insecticide resistance in Anopheles vectors from 48 districts of Uganda.
Amy Lynd, Samuel Gonahasa, Sarah G Staedke, Ambrose Oruni, Catherine Maiteki-Sebuguzi, Adoke Yeka

Sci Rep· June 2024

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Correction: Limitations of rapid diagnostic tests in malaria surveys in areas with varied transmission intensity in Uganda 2017-2019: Implications for selection and use of HRP2 RDTs.
Bosco B Agaba, Joaniter I Nankabirwa, Adoke Yeka, Sam Nsobya, Karryn Gresty

PLoS One· May 2024

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Impact of population based indoor residual spraying in combination with mass drug administration on malaria incidence and test positivity in a high transmission setting in north eastern Uganda.
Mulebeke Ronald, Wanzira Humphrey, Yeka Adoke, Van Geertruyden Jean-Pierre

Malar J· December 2023

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Ganaplacide (KAF156) plus lumefantrine solid dispersion formulation combination for uncomplicated Plasmodium falciparum malaria: an open-label, multicentre, parallel-group, randomised, controlled, phase 2 trial.
Bernhards Ogutu, Adoke Yeka, Sylvia Kusemererwa, Ricardo Thompson, Halidou Tinto

Lancet Infect Dis· September 2023

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LLIN Evaluation in Uganda Project (LLINEUP) - infection prevalence and genotypic markers of insecticide resistance in vectors from 48 districts of Uganda.
Amy Lynd, Samuel Gonahasa, Sarah G Staedke, Ambrose Oruni, Catherine Maiteki-Sebuguzi, Adoke Yeka

medRxiv· August 2023

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Impact of population based indoor residual spraying with and without mass drug administration with dihydroartemisinin-piperaquine on malaria prevalence in a high transmission setting: a quasi-experimental controlled before-and-after trial in northeastern Uganda.
Dorothy C Echodu, Adoke Yeka, Thomas Eganyu, Wycliff Odude, Fred Bukenya

BMC Infect Dis· February 2023

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African-specific polymorphisms in serine repeat antigen 5 in Uganda and Burkina Faso clinical samples do not interfere with antibody response to BK-SE36 vaccination.
Nobuko Arisue, Nirianne Marie Q Palacpac, Edward H Ntege, Adoke Yeka, Betty Balikagala

Front Cell Infect Microbiol· January 2023

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Randomized, open-label, phase 2a study to evaluate the contribution of artefenomel to the clinical and parasiticidal activity of artefenomel plus ferroquine in African patients with uncomplicated Plasmodium falciparum malaria.
Adama Gansane, Moussa Lingani, Adoke Yeka, Alain Nahum, Marielle Bouyou-Akotet

Malar J· January 2023

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Factors influencing consistent use of bed nets for the control of malaria among children under 5 years in Soroti District, North Eastern Uganda.
Anne Ruth Akello, John Paul Byagamy, Samuel Etajak, Charles Stephen Okadhi, Adoke Yeka

Malar J· December 2022

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Efficacy of Cipargamin (KAE609) in a Randomized, Phase II Dose-Escalation Study in Adults in Sub-Saharan Africa With Uncomplicated Plasmodium falciparum Malaria.
Esther K Schmitt, Gilles Ndayisaba, Adoke Yeka, Kwaku Poku Asante, Martin P Grobusch

Clin Infect Dis· May 2022

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LLIN evaluation in Uganda project (LLINEUP): The fabric integrity, chemical content and bioefficacy of long-lasting insecticidal nets treated with and without piperonyl butoxide across two years of operational use in Uganda.
Frank Mechan, Agaba Katureebe, Violet Tuhaise, Martin Mugote, Ambrose Oruni, Adoke Yeka

Curr Res Parasitol Vector Borne Dis· May 2022

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Correction to: Efficacy and safety of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria and prevalence of molecular markers associated with artemisinin and partner drug resistance in Uganda.
Chris Ebong, Asadu Sserwanga, Jane Frances Namuganga, James Kapisi, Arthur Mpimbaza, Adoke Yeka

Malar J· February 2022

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Hepatic safety and tolerability of cipargamin (KAE609), in adult patients with Plasmodium falciparum malaria: a randomized, phase II, controlled, dose-escalation trial in sub-Saharan Africa.
Gilles Ndayisaba, Adoke Yeka, Kwaku Poku Asante, Martin P Grobusch, Etienne Karita

Malar J· December 2021

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Efficacy and safety of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria and prevalence of molecular markers associated with artemisinin and partner drug resistance in Uganda.
Chris Ebong, Asadu Sserwanga, Jane Frances Namuganga, James Kapisi, Arthur Mpimbaza, Adoke Yeka

Malar J· December 2021

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Genetic diversity and genetic relatedness in Plasmodium falciparum parasite population in individuals with uncomplicated malaria based on microsatellite typing in Eastern and Western regions of Uganda, 2019-2020.
Bosco B Agaba, Karen Anderson, Karryn Gresty, Christiane Prosser, David Smith, Adoke Yeka

Malar J· May 2021

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